Atorvastatin

Umxholo

• Ngaphambi kokuba uthathe i-atorvastatin,
• I-Atorvastatin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha okanye ufumane uncedo lonyango ngokukhawuleza:

I-Atorvastatin isetyenziswa kunye nokutya, ukwehla kobunzima, kunye nokuzilolonga ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo kunye nokubetha kunye nokwehlisa ithuba lokuba kufuneka utyando lwentliziyo kubantu abanesifo sentliziyo okanye abasemngciphekweni wokuhlaselwa sisifo sentliziyo. I-Atorvastatin ikwasetyenziselwa ukunciphisa isixa sezinto ezinamafutha ezinje nge-low-density lipoprotein (LDL) cholesterol ('bad cholesterol') kunye ne-triglycerides egazini kunye nokunyusa inani le-lipoprotein (HDL) cholesterol ('cholesterol elungileyo' ') egazini. I-Atorvastatin inokusetyenziselwa ukunciphisa inani le-cholesterol kunye nezinye izinto ezinamafutha egazini ebantwaneni nakwishumi elivisayo abaneminyaka eli-10 ukuya kweli-17 ubudala abane-heterozygous hypercholesterolemia (imeko ezuzwe njengelifa apho i-cholesterol ayinakususwa emzimbeni ngesiqhelo). I-Atorvastatin ikwiklasi yamayeza abizwa ngokuba yi-HMG-CoA reductase inhibitors (statins). Isebenza ngokunciphisa imveliso ye-cholesterol emzimbeni ukunciphisa inani le-cholesterol elinokwakha kwiindonga zeemithambo kunye nokuvimba ukuhamba kwegazi ukuya entliziyweni, kwingqondo nakwezinye iindawo zomzimba.

Ukuqokelelwa kwecholesterol kunye namafutha ecaleni kweendonga zemithambo yakho (inkqubo eyaziwa njenge-atherosclerosis) inciphisa ukuhamba kwegazi kwaye, ke, unikezelo lweoksijini entliziyweni yakho, kwingqondo nakwamanye amalungu omzimba wakho. Ukunciphisa inqanaba legazi le-cholesterol kunye namafutha nge-atorvastatin kubonisiwe ukuthintela isifo sentliziyo, i-angina (iintlungu zesifuba), ukubetha, kunye nokuhlaselwa yintliziyo.

I-Atorvastatin iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-atorvastatin malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-atorvastatin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokukuqala ngedosi esezantsi ye-atorvastatin kwaye ngokuthe ngcembe yonyuse idosi yakho, hayi ngaphezulu kwesinye kwiiveki ezi-2 ukuya kwezi-4.

Qhubeka uthathe i-atorvastatin nokuba uziva uphilile. Sukuyeka ukuthatha i-atorvastatin ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-atorvastatin,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-atorvastatin, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-atorvastatin. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza okubola njenge-itraconazole (Sporanox) kunye ne-ketoconazole (Nizoral); I-boceprevir (iVictrelis); cimetidine (iTagamet); i-clarithromycin (i-Biaxin); amayeza e-cobicistat (Stribild); icolchicine (iiColcrys); idigoxin (Lanoxin); efavirenz (Sustiva, eAtripla); izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa); amanye amayeza anciphisa i-cholesterol njenge-fenofibrate (Tricor), gemfibrozil (Lopid), kunye ne-niacin (nicotinic acid, Niacor, Niaspan); ezithile ze-HIV protease inhibitors ezinjenge darunavir (Prezista), fosamprenavir (Lexiva), lopinavir (e Kaletra), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), saquinavir (Invirase), kunye netipranavir (Aptivus); amayeza athintela amajoni omzimba anje ngecyclosporine (Neoral, Sandimmune); irifampin (Rifadin, Rimactane); i-spironolactone (Aldactone); kunye netelaprevir (Incivek). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza anokusebenzisana ne-atorvastatin, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba unesifo sesibindi. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu ukuze abone ukuba isibindi sakho sisebenza kakuhle kangakanani nokuba awucingi ukuba unesifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-atorvastatin ukuba unayo okanye unesifo sesibindi okanye ukuba iimvavanyo zibonisa ukuba unokuba nesifo sesibindi.
• xelela ugqirha wakho ukuba usela ngaphezu kwezi-2 iziselo ezinxilisayo yonke imihla, ukuba uneminyaka engama-65 ubudala okanye ngaphezulu, ukuba wakhe waba nesifo sesibindi, kwaye ukuba ukhe wanamahlaba emithambo okanye ubuthathaka; isifo seswekile, ukuxhuzula, uxinzelelo lwegazi, okanye isifo segilo okanye isifo sezintso.

• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa uthatha i-atorvastatin. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwe ngelixa uthatha i-atorvastatin, yeka ukuthatha i-atorvastatin kwaye ubize ugqirha ngokukhawuleza. I-Atorvastatin inokwenzakalisa umntwana ongekazalwa.

  
  

• musa ukuncancisa xa uthatha la mayeza.

• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-atorvastatin. Ukuba ulaliswe esibhedlele ngenxa yokulimala kakhulu okanye usulelo, xelela ugqirha okunyangayo ukuba uthatha i-atorvastatin.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kweziselo ezinxilisayo ngelixa uthatha i-atorvastatin. Utywala bunokunyusa umngcipheko weziphumo ebezingalindelekanga ezimandundu.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Kunqabe ukusela isixa esikhulu [ngaphezulu kwe-1.2 yeelitha (malunga nekota enye) ngemini] yejusi yeziqhamo zomdiliya ngelixa uthatha i-atorvastatin.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 kude kube yidosi elandelayo ehleliweyo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Atorvastatin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• isilungulela
• irhasi
• intlungu edibeneyo
• ukulibala okanye ukulahleka kwememori
• ukudideka

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha okanye ufumane uncedo lonyango ngokukhawuleza:

• iintlungu zemisipha, ukuthamba, okanye ubuthathaka
• ukunqongophala kwamandla
• ifiva
• iintlungu zesifuba
• isicaphucaphu
• ukudinwa kakhulu
• ubuthathaka
• ukopha okungaqhelekanga okanye ukugruzuka
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• Iimpawu ezinjengomkhuhlane
• umchamo omnyama ngombala
• mthubi ulusu okanye amehlo
• irhashalala
• urhwebo
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa

I-Atorvastatin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unoku-odola uvavanyo oluthile lweelebhu ngexesha lonyango lwakho, ngakumbi ukuba uvelisa iimpawu zomonakalo wesibindi.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-atorvastatin.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Lipitor^®

• Isidanga^® (Iqulethe i-Amlodipine, Atorvastatin)
• ILiptruzet^® (iqulethe iAtorvastatin, i-Ezetimibe)