Umbhali: William Ramirez
Umhla Wokudalwa: 23 Eyomsintsi 2021
Hlaziya Umhla: 13 Eyenkanga 2024
Anonim
Fenofibrate - Mechanism, side effects, interactions and contraindications
Ividiyo: Fenofibrate - Mechanism, side effects, interactions and contraindications

Umxholo

I-Fenofibrate isetyenziselwa ukutya okunamafutha asezantsi, ukuzilolonga, kwaye ngamanye amaxesha namanye amayeza ukunciphisa isixa sezinto ezinamanqatha ezinjenge-cholesterol kunye ne-triglycerides egazini kunye nokunyusa inani le-HDL (high-density lipoprotein; uhlobo lwento enamafutha oko kunciphisa umngcipheko wesifo sentliziyo) egazini. Ukwakhiwa kwecholesterol kunye namafutha ecaleni kweendonga zemithambo (inkqubo eyaziwa njenge-atherosclerosis) inciphisa ukuhamba kwegazi kwaye, ke, unikezelo lweoksijini entliziyweni, kwingqondo nakwamanye amalungu omzimba. Oku kwandisa umngcipheko wesifo sentliziyo, i-angina (iintlungu zesifuba), ukubetha, kunye nokuhlaselwa sisifo sentliziyo. Nangona i-fenofibrate inciphisa amanqanaba ezinto ezinamafutha egazini, ayiboniswanga ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo okanye ukubetha. I-Fenofibrate ikwiklasi yamayeza abizwa ngokuba ziiarhente ze-antilipemic. Isebenza ngokukhawulezisa iinkqubo zendalo ezisusa i-cholesterol emzimbeni.

I-Fenofibrate iza njengecapsule, ukukhutshwa kokulibaziseka (ukusebenza ixesha elide) kunye necwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini. Ezinye iimveliso ze-fenofibrate (i-Fenoglide, i-Lipofen, ne-Lofibra) kufuneka zithathwe kunye nesidlo. Ezinye iintlobo (iAntara, iFibricor, iTricor, iTriglide, kunye neTrilipix) zinokuthathwa kunye okanye ngaphandle kokutya. Buza ugqirha wakho okanye usokhemesti ukuba awazi ukuba kufuneka uthathe amayeza akho ngokutya. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-fenofibrate ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.


Ugqirha wakho uya kukuqala ngeqondo eliphakathi le-fenofibrate kwaye unokunyusa okanye anciphise idosi yakho ngokuxhomekeke kwiziphumo zovavanyo lwelabhoratri oza kulithatha ukulinganisa inani lezinto ezinamanqatha egazini lakho. Ugqirha wakho angakuxelela ukuba uyeke ukuthatha i-fenofibrate ukuba iziphumo zakho zovavanyo azibonisi ukuphucula emva kweenyanga ezimbini.

Ginya iipilisi zokukhululwa ezilibazisekileyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uthatha iipilisi zeTriglide, musa ukusebenzisa naziphi na iipilisi ezitshiweyo okanye ezaphukileyo.

I-Fenofibrate iya kunceda ukunciphisa inani lezinto ezinamafutha egazini lakho kuphela ukuba uqhubeka uyithatha. Qhubeka nokuthatha i-fenofibrate nokuba uziva uphilile. Ungayeki ukuthatha i-fenofibrate ngaphandle kokuthetha nogqirha wakho.

La mayeza angamiselwa ezinye izinto. Buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-fenofibrate,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nayo nayiphi na imveliso ye-fenofibrate, nawaphi na amanye amayeza, okanye nasiphi na isithako kwimveliso yefenofibrate oyithathayo. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, okanye iimveliso zamayeza ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin); icolchicine (Colcrys, kwiCol-Probenecid); umchamo ('iipilisi zamanzi'); ii-beta blockers ezinje nge-atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), kunye nepropranolol (Inderal); I-HMG-CoA reductase inhibitors (ii-cholesterol-lowering agents) ezifana ne-atorvastatin (Lipitor), lovastatin (Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), kunye ne-simvastatin (iZocor); Unyango lwehormone; izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iziqwengana, izinto zokufakelwa, amakhonkco kunye nenaliti); kunye ne-immunosuppressants ezinje ngecyclosporine (iSandimmune, Neoral) kunye ne-tacrolimus (Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • ukuba uthatha i-bile acid resin efana necholestyramine (Questran), colesevelam (WelChol), okanye colestipol (Colestid), yithathe iyure e-1 emva okanye kwiiyure ezi-4-6 ngaphambi kokuba uthathe i-fenofibrate.
  • xelela ugqirha wakho ukuba ukhe unesifo sezintso, isibindi, okanye inyongo. Ugqirha wakho uya kukuxelela ukuba ungathathi i-fenofibrate.
  • xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala kwaye ukuba unesifo seswekile okanye i-hypothyroidism (i-thyroid gland).
  • xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwe ngelixa uthatha i-fenofibrate, biza ugqirha wakho.
  • xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa uthatha i-fenofibrate.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Fenofibrate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ukuqhina
  • urhudo
  • isilungulela
  • iintlungu emqolo, engalweni, okanye emilenzeni
  • intloko ebuhlungu
  • intlungu edibeneyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

  • iintlungu zemisipha, ubuthathaka, okanye ukuthamba; ifiva
  • ukudumba okanye ukuxobuka kolusu
  • irhashalala; ifiva; ingxaki yokuphefumla; utshintsho kwimchamo; intlungu zesisu
  • urhwebo
  • iintlungu kumqolo ongaphezulu phakathi kwamagxa okanye phantsi kwegxalaba lasekunene; isisu esibuhlungu, ngakumbi kwinxalenye ephezulu yesisu; isicaphucaphu; ukugabha
  • ubomvu, ukudumba, iintlungu, ukuthamba, okanye ukufudumala kumlenze omnye
  • ukuqhawukelwa ngumphefumlo; iintlungu xa uphefumla; ukhohlela igazi
  • ukudumba kobuso, umqala, ulwimi, imilebe namehlo; ubunzima bokuginya okanye ukuphefumla; ukudinwa

I-Fenofibrate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa uthatha i-fenofibrate.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zaselebhu ukujonga impendulo yakho kwi-fenofibrate.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Antara®
  • Ifenoglide®
  • Lipidil®
  • I-Lipofen®
  • TriCor®
  • Ukubangela®
  • I-Trilipix®

Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.

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