Umbhali: Gregory Harris
Umhla Wokudalwa: 15 Utshazimpuzi 2021
Hlaziya Umhla: 18 Eyenkanga 2024
Anonim
Olanzapine - Mechanism, side effects and precautions
Ividiyo: Olanzapine - Mechanism, side effects and precautions

Umxholo

Izifundo zibonise ukuba abantu abadala abanesifo sengqondo esixhalabisayo (ukuphazamiseka kwengqondo okuchaphazela amandla okukhumbula, ukucinga ngokucacileyo, ukunxibelelana, nokwenza imisebenzi yemihla ngemihla kwaye kunokubangela utshintsho kwiimvakalelo nakubuntu) abathatha ii-antipsychotic (amayeza esigulo sengqondo) njenge-olanzapine banamathuba amaninzi okufa ngexesha lonyango. Abantu abadala abanesifo sengqondo esixhalabisayo banokuba nethuba elikhulu lokuba nesifo sokubethwa okanye ukubetha kancinci ngexesha lonyango.

I-Olanzapine ayamkelwa luLawulo lwezoKutya kunye noLawulo lweziyobisi (i-FDA) kunyango lweengxaki zokuziphatha kubantu abadala abanesifo sengqondo esiyingozi. Thetha nogqirha okumisele la mayeza ukuba wena, ilungu losapho, okanye umntu omkhathalelayo unesifo sengqondo esixhalabisayo kwaye uthatha i-olanzapine. Ngolwazi oluthe kratya ndwendwela iwebhusayithi ye-FDA: http://www.fda.gov/Drugs

I-Olanzapine isetyenziselwa ukunyanga iimpawu zeschizophrenia (isifo sengqondo esibangela ukuphazamiseka okanye ukucinga okungaqhelekanga, ukuphelelwa ngumdla ebomini, kunye neemvakalelo ezinamandla okanye ezingalunganga) kubantu abadala nakwishumi elivisayo abaneminyaka eli-13 ubudala nangaphezulu. Isetyenziselwa ukunyanga isifo esiyi-bipolar (isifo sokudakumba (manic depress disorder); isifo esibangela iziqendu zoxinzelelo, iziqendu ze-mania, kunye nezinye izinto ezingaqhelekanga) kubantu abadala nakwishumi elivisayo abaneminyaka eli-13 ubudala nangaphezulu. U-Olanzapine ukwiklasi yamayeza abizwa ngokuba yi-atypical antipsychotic. Isebenza ngokutshintsha umsebenzi wezinto ezithile zendalo kwingqondo.


I-Olanzapine iza njengecwecwe kunye necwecwe lokuqhekeka ngomlomo (ithebhulethi inyibilika ngokukhawuleza emlonyeni) ukuyithatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-olanzapine malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-olanzapine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ungazami ukutyhala ithebhulethi yokuqhekeza ngomlomo ngefoyile. Endaweni yoko, sebenzisa izandla ezomileyo ukukhupha iipakethi zeefoyile. Khawuleza ukhuphe icwecwe ulibeke emlonyeni wakho. Ithebhulethi iya kunyibilika ngokukhawuleza kwaye inokuginywa okanye ngaphandle kolwelo.

Ugqirha wakho unokukuqala kwidosi ephantsi ye-olanzapine kwaye ngokuthe ngcembe wandise idosi yakho.

I-Olanzapine inokunceda ukulawula iimpawu zakho, kodwa ayizukuyinyanga imeko yakho. Ingathatha iiveki ezininzi okanye ngaphezulu ngaphambi kokuba uve isibonelelo se-olanzapine. Qhubeka nokuthatha i-olanzapine nokuba uziva uphilile. Sukuyeka ukuthatha i-olanzapine ngaphandle kokuthetha nogqirha wakho. Ugqirha wakho uya kufuna ukunciphisa umthamo wakho ngokuthe ngcembe.


Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-olanzapine,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-olanzapine okanye amanye amayeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: antihistamines; carbamazepine (Tegretol); Iidopamine agonists ezinje ngebromocriptine (Parlodel), cabergoline (Dostinex), levodopa (Dopar, Larodopa), pergolide (Permax), kunye ropinirole (Requip); i-fluoroquinolone antibiotics iquka i-ciprofloxacin (Cipro), gatifloxacin (Tequin) (ayifumaneki e-United States), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), abanye; i-fluvoxamine (iLuvox); ipratropium (Atrovent); amayeza oxinzelelo, uxinzelelo oluphezulu lwegazi, isifo sesisu, isifo sengqondo, ukugula, isifo sikaParkinson, ukuxhuzula, izilonda, okanye iingxaki zomchamo; omeprazole (Prilosec); irifampin (Rifadin); ukuthomalalisa; iipilisi zokulala; i-ticlopidine (iTiclid); kunye noxinzelelo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba usebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni okanye wasebenzisa kakhulu amayeza kagqirha kwaye ukuba ukhe wahlaselwa sistroke, ukubethwa kancinci, isifo sentliziyo okanye isifo sentliziyo, ukubetha kwentliziyo ngokungaqhelekanga, ukusilela kwentliziyo, iingxaki zomchamo, ukuxhuzula, umhlaza webele, nayiphi na imeko eyenza kube nzima ukuba uyiginye, unengxaki yokugcina ibhalansi, uxinzelelo lwegazi oluphezulu okanye oluphantsi, inqanaba eliphezulu lamafutha (cholesterol kunye ne-triglycerides) egazini lakho, inani eliphantsi leeseli ezimhlophe zegazi, isibindi okanye isifo seprostate, ileus ekhubazekileyo (imeko apho ukutya kungahambi emathunjini); i-glaucoma (imeko yamehlo), okanye iswekile ephezulu yegazi, okanye ukuba wena okanye nabani na kusapho lwakho ukhe unesifo seswekile. Xelela ugqirha wakho ukuba unesifo sokuqhinwa, ukugabha kakhulu okanye urhudo okanye iimpawu zokoma emzimbeni ngoku, okanye ukuba uziphuhlisa ezi mpawu nanini na ngexesha lonyango lwakho. Xelela ugqirha wakho ukuba ukhe uyeke ukuthatha iyeza lokugula ngengqondo ngenxa yeziphumo ebezingalindelekanga ezibi.
  • xelela ugqirha wakho ukuba ukhulelwe, ngakumbi ukuba ukwinyanga ezimbalwa ezidlulileyo zokukhulelwa kwakho, okanye ukuba ucwangcisa ukukhulelwa okanye ukuncancisa. Ukuba ukhulelwa ngelixa uthatha i-olanzapine, tsalela umnxeba ugqirha wakho. I-Olanzapine inokubangela iingxaki kwiintsana ezisanda kuzalwa emva kokubeleka ukuba zithathiwe kwiinyanga zokugqibela zokukhulelwa.
  • ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-olanzapine.
  • Kuya kufuneka uyazi ukuba i-olanzapine inokukwenza wozele. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
  • Kuya kufuneka uyazi ukuba utywala bunokongeza ukozela okubangelwa leli yeza. Musa ukusela utywala ngelixa uthatha i-olanzapine.
  • xelela ugqirha wakho ukuba usebenzisa iimveliso zecuba. Ukutshaya icuba kunokunciphisa ukusebenza kweli yeza.
  • Kuya kufuneka uyazi ukuba unokufumana i-hyperglycemia (inyuka kwiswekile esegazini lakho) ngelixa uthatha eli yeza, nokuba awukabinaso isifo seswekile. Ukuba une-schizophrenia, kunokwenzeka ukuba ube nesifo seswekile kunabantu abangenayo i-schizophrenia, kwaye ukuthatha i-olanzapine okanye amayeza afanayo kunokuwunyusa lo mngcipheko. Xelela ugqirha wakho kwangoko ukuba unayo kwezi mpawu zilandelayo ngelixa uthatha i-olanzapine: ukunxanwa okugqithisileyo, ukuchama rhoqo, indlala egqithisileyo, umbono ophuthileyo, okanye ubuthathaka. Kubaluleke kakhulu ukubiza ugqirha wakho nje ukuba ufumane naziphi na kwezi mpawu, kuba iswekile eninzi egazini inokubangela imeko embi ebizwa ngokuba yi ketoacidosis. I-Ketoacidosis inokuba sengozini yobomi ukuba ayinyangwa kwangoko. Iimpawu zeketoacidosis zibandakanya: umlomo owomileyo, isicaphucaphu kunye nokugabha, ukuphefumla kancinci, umphefumlo onuka iziqhamo, kunye nokwehla kwengqondo.
  • Kuya kufuneka uyazi ukuba i-olanzapine inokubangela ukubetha kwentliziyo okukhawulezayo okanye okucothayo, ukuba nesiyezi, ukuba sentloko, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo olele kuyo. Oku kuqheleke ngakumbi xa uqala ukuthatha i-olanzapine. Ukuthintela le ngxaki, phuma kancinci ebhedini, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.
  • Kuya kufuneka uyazi ukuba i-olanzapine inokwenza kube nzima ukuba umzimba wakho uphole xa kushushu kakhulu. Tshela ugqirha wakho ukuba ucwangcisa ukwenza umthambo ngamandla okanye uvezwe bubushushu obugqithisileyo.
  • ukuba une-phenylketonuria (PKU, imeko ekuyo njengelifa apho ukutya okukhethekileyo kufuneka kulandelwe ukuthintela ukudodobala kwengqondo), kuya kufuneka wazi ukuba amacwecwe odilikayo ngomlomo ane-aspartame eyenza i-phenylalanine.
  • Kuya kufuneka uyazi ukuba xa i-olanzapine isetyenziselwa ukunyanga ulutsha, kufuneka isetyenziswe njengenxalenye yenkqubo yonyango iyonke enokubandakanya ukucebisa kunye nenkxaso kwezemfundo. Qinisekisa ukuba umntwana wakho ulandela yonke imiyalelo kagqirha kunye / okanye yonyango.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yegrapefruit ngelixa uthatha eli yeza.


Qiniseka ukuba usele amanzi amaninzi yonke imihla ngelixa usela la mayeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Olanzapine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isiyezi, ukuziva ungazinzanga, okanye unengxaki yokugcina ibhalansi yakho
  • ukungazinzi
  • isimilo esingaqhelekanga
  • ukudakumba
  • ubunzima bokulala okanye ukulala
  • ubuthathaka
  • ubunzima bokuhamba
  • ukuqhina
  • ukutyeba kwakho
  • umlomo owomileyo
  • iintlungu ezingalweni, emilenzeni, ngasemva, okanye kumalungu
  • ukwandiswa kwamabele okanye ukukhupha
  • ukuya emva kwexesha okanye ukuphoswa lixesha lokuya exesheni
  • ukunciphisa amandla esini

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye icandelo LOKULUMKELA OKUKHETHEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

  • ukuxhuzula
  • utshintsho kumbono
  • ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
  • iintshukumo ezingaqhelekanga zobuso bakho okanye zomzimba ongenakuzilawula
  • ukuwa
  • umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
  • izihlunu eziqinileyo kakhulu
  • ukubila okugqithisileyo
  • ukukhawuleza kwentliziyo okanye okungaqhelekanga
  • ukukhawuleza okungenzeka ngomkhuhlane, ukuvuvukala kwamadlala, okanye ukudumba kobuso
  • ubomvu bomzimba okanye ukuxobuka
  • urhwebo
  • ubunzima bokuphefumla okanye ukugwinya

I-Olanzapine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuthatha i-olanzapine kunokubangela inqanaba lamafutha egazini lakho ukuba lonyuke. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-olanzapine.

Abakwishumi elivisayo abathatha i-olanzapine kunokwenzeka ngakumbi kunabantu abadala abathatha i-olanzapine ukutyeba, baye bonyusa amanqanaba amanqatha egazini labo, baba neengxaki zesibindi, kwaye bafumane iziphumo ebezingalindelekanga njengokulala, ukwanda kwamabele, kunye nokukhutshwa emabeleni. Thetha nogqirha womntwana wakho malunga neengozi zokunyanga umntwana wakho nge-olanzapine. Ugqirha womntwana wakho unokukhetha ukumisela amayeza ahlukeneyo angenayo le mingcipheko.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Ngalo lonke ixesha gcina amacwecwe odilikayo ngomlomo kwiphakheji yawo etywiniweyo, kwaye uyisebenzise kwangoko emva kokuvula iphakheji.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • ukozela
  • intetho engacacanga
  • ukuphazamiseka
  • ukubetha kwentliziyo ngokukhawuleza
  • iintshukumo ngequbuliso ongenakuzilawula
  • isiqaqa (ukulahleka kwengqondo ixesha elithile)

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-olanzapine.

Musa ukuvumela nabani na ukuba athathe amayeza akho.Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Zyprexa®
  • Zyprexa® Zydis
  • Uphawu® (iqulethe iFluoxetine, iOlanzapine)
Ukuhlaziywa kokugqibela-06/15/2020

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