Umbhali: Marcus Baldwin
Umhla Wokudalwa: 17 Isilimela 2021
Hlaziya Umhla: 16 Eyenkanga 2024
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Mnemonic of the day -  Pharmacology IBS drugs - ALOSETRON | Dr.Nikita Nanwani
Ividiyo: Mnemonic of the day - Pharmacology IBS drugs - ALOSETRON | Dr.Nikita Nanwani

Umxholo

I-Alosetron inokubangela isisu esinzulu (GI; ichaphazela isisu okanye amathumbu) iziphumo ebezingalindelekanga kubandakanya ischemic colitis (ukwehla kokuhamba kwegazi ukuya emathunjini) kunye nokuqhinwa okunzima okungafuna ukunyangwa esibhedlele kwaye akunakufane kubangele ukufa. Xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo: antihistamines; ezinye izidambisi zengqondo ('mood elevators') ezibizwa ngokuba yi-tricyclic antidepressants; okanye amayeza athile okunyanga isifuba, isifo sorhudo, isifo semiphunga, ukugula ngengqondo, ukugula okushukumayo, isinyi esisebenzayo, iintlungu, isifo sikaParkinson, isisu okanye amahlaba esiswini, izilonda kunye nesisu esibuhlungu. Xelela ugqirha wakho ukuba uyabambeka ngoku, ukuba uhlala unengxaki yokuqhinwa, okanye ukuba unengxaki ebangelwa kukuqhinwa. Xelela ugqirha wakho ukuba unesithintelo emathunjini akho, ischemic colitis, amahlwili egazi, okanye nasiphi na isifo esibangela ukudumba kwamathumbu anjengesifo sikaCrohn (ukudumba kwenxalenye yendlela yokugaya ukutya), ulcerative colitis (imeko ebangela ukudumba kunye nezilonda kumngxunya wekholoni [amathumbu amakhulu] kunye ne-rectum), i-diverticulitis (iipokotho ezincinci kuludwe lwamathumbu amakhulu anokutsha) okanye isifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-alosetron.


Yeka ukuthatha i-alosetron kwaye ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: ukuqhina, iintlungu ezintsha okanye ezimbi esiswini (esiswini), okanye igazi ekuhambeni kwakho kwamathumbu. Fowunela ugqirha wakho kwakhona ukuba ukuqhinwa kwakho akuyi kuba ngcono emva kokuba uyekile ukuthatha i-alosetron. Nje ukuba uyeke ukuthatha i-alosetron ngenxa yezi mpawu, ungaqali ukuyithatha kwakhona ngaphandle kokuba ugqirha ukuxelele ukuba kufanele.

Kuphela ngoogqirha abathile ababhalisiweyo kwinkampani eyenza i-alosetron kwaye abazi ngeziphumo ebezingalindelekanga ezinokubhalwa. Ugqirha wakho uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) ngaphambi kokuba uqale unyango nge-alosetron kwaye usokhemesti wakho uya kukunika ikopi ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungasifumana isiKhokelo seMithi kwiwebhusayithi yoLawulo lwezoKutya noLawulo lweziyobisi (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi.


Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-alosetron.

I-Alosetron isetyenziselwa ukunyanga isifo sohudo, iintlungu, iicramps, kunye nemvakalelo yesidingo esingxamisekileyo sokuhamba kwamathumbu okubangelwa sisifo samathumbu (IBS; imeko ebangela iintlungu zesisu, ukuqunjelwa, ukuqunjelwa, kunye norhudo) kwabasetyhini abanesifo sohudo njenge uphawu lwabo oluphambili kwaye khange bancedwe lolunye unyango. IAlosetron ikudidi lwamayeza abizwa ngokuba yi-5-HT3 abachasi be-receptor. I-Alosetron isebenza ngokucothisa ukuhamba kwesitulo (ukuhamba kwamathumbu) emathunjini.

I-Alosetron iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kabini ngemini kunye okanye ngaphandle kokutya. Thatha i-alosetron ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-alosetron ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho uya kukuqala ngeqondo eliphantsi le-alosetron. Ugqirha wakho uya kufuna ukuthetha nawe emva kokuba uthathe idosi esezantsi kwiiveki ezi-4. Ukuba iimpawu zakho azilawulwa kodwa awunazo iziphumo ebezingalindelekanga zealosetron, ugqirha wakho unokunyusa idosi yakho. Ukuba uthatha idosi eyonyukileyo yeeveki ezi-4 kwaye iimpawu zakho azikalawulwa, i-alosetron ayinakukunceda. Yeka ukuthatha i-alosetron kwaye ubize ugqirha wakho.


I-Alosetron inokulawula i-IBS kodwa ayizukuyinyanga. Ukuba i-alosetron ikunceda kwaye uyeke ukuyithatha, iimpawu zakho ze-IBS zinokubuya zingaphelanga iiveki ezi-1 okanye ezi-2.

I-Alosetron akufuneki imiselwe ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-alosetron,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-alosetron, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-alosetron. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho ukuba uthatha i-fluvoxamine (i-Luvox) okanye amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, ugqirha wakho uya kuthi kuwe ungathathi i-alosetron ukuba uthatha elinye okanye ngaphezulu kula mayeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-antifungals ezithile ezifana ne-fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), kunye ne-voriconazole (Vfend); cimetidine (iTagamet); i-clarithromycin (i-Biaxin, kwi-Prevpac); i-fluoroquinolone antibiotics kubandakanya i-ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), abanye; hydralazine (apresoline); isoniazid (INH, Nydrazid); amayeza athile kwintsholongwane kaGawulayo (i-HIV) okanye i-immunodeficiency syndrome (i-AIDS) efana ne-atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (eKaletra), nelfinavir (Viracept), ritonavir (ENorvir, eKaletra), saquinavir (Fortovase, Invirase), kunye netipranavir (Aptivus); Ukufumana kwakhona (iProcanbid, Pronestyl); kunye ne-telithromycin (Ketek). Uninzi lwamanye amayeza anokusebenzisana ne-alosetron, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ngaba wakha wanazo na iimeko ezidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye nasiphi na isisu okanye iingxaki zesisu, utyando esiswini sakho okanye amathumbu, okanye isifo sezintso.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-alosetron, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Musa ukuthatha idosi ephosiweyo xa uyikhumbula. Tsiba idosi ephosiweyo kwaye uthathe idosi elandelayo ngexesha elimiselweyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Alosetron inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isisu esimoshakele
  • ukudumba kwindawo yesisu
  • Iimpawu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iimpawu ezidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Ilotronex®
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