Mefloquine

Umxholo

• Ngaphambi kokuba uthathe i-mefloquine,
• I-Mefloquine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba unazo naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye EZIQHELEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Mefloquine inokubangela iziphumo ebezingalindelekanga ezimandundu ezibandakanya utshintsho kwinkqubo yemithambo-luvo. Tshela ugqirha wakho ukuba ukhe waxhuzula. Ugqirha wakho unokukuxelela ukuba ungathathi i-mefloquine. Ukuba uqaphela naluphi na olu phawu lulandelayo ngelixa uthatha eli yeza, biza ugqirha ngokukhawuleza: isiyezi, imvakalelo yokuba wena okanye izinto ezikungqongileyo zihamba okanye zijikeleza, kukhala ezindlebeni, kunye nelahleko yokulinganisela. Ezi mpawu zinokwenzeka nangaliphi na ixesha ngelixa uthatha i-mefloquine kwaye inokuhlala iinyanga ukuya kwiminyaka emva kokuba iyeza limisiwe okanye linokuhlala ngokusisigxina.

I-Mefloquine inokubangela iingxaki zempilo yengqondo. Tshela ugqirha wakho ukuba ukhe wanalo uxinzelelo, unxunguphalo, isifo sengqondo (kunzima ukucinga ngokucacileyo, ukuqonda ubunyani, ukunxibelelana nokuziphatha ngokufanelekileyo), isifo sengqondo (isifo esibangela ukuphazamiseka okanye ukucinga okungaqhelekanga, ukuphelelwa ngumdla ebomini, kunye iimvakalelo ezingalunganga) okanye ezinye iingxaki zempilo yengqondo. Xelela ugqirha wakho kwangoko ukuba uvelisa ezi mpawu zilandelayo ngelixa uthatha amayeza: uxinzelelo, iimvakalelo zokungathembi abanye, ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho), uxinzelelo, iingcinga zokuzibulala okanye ukuzenzakalisa, ukungazinzi, ukudideka, ubunzima bokulala okanye ukulala, okanye isimilo esingaqhelekanga. Ezi mpawu zinokubakho nangaliphi na ixesha ngelixa uthatha i-mefloquine kwaye inokuhlala iinyanga ukuya kwiminyaka emva kokuba iyeza limisiwe.

Ezi mpawu zotshintsho lwenkqubo yemithambo-luvo okanye iingxaki zempilo yengqondo kunokuba nzima ngakumbi ukuzibona kubantwana abancinci. Jonga umntwana wakho ngononophelo kwaye unxibelelane nogqirha wakhe ngoko nangoko ukuba ufumana naluphi na utshintsho kwindlela yokuziphatha okanye kwezempilo.

Gcina konke ukuqeshwa nogqirha wakho, ugqirha wamehlo, kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zelebhu kunye nokuhlolwa kwamehlo ngamaxesha athile ukujonga impendulo yomzimba wakho kwi-mefloquine.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-mefloquine kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-mefloquine.

IMefloquine isetyenziselwa ukunyanga isifo seengcongconi (isifo esosulelayo esisasazwa ziingcongconi kwiindawo ezithile zehlabathi kwaye sinokubangela ukufa) kunye nokuthintela isifo seengcongconi kubahambi abatyelela iindawo apho isifo seengcongconi sixhaphake khona. IMefloquine ikudidi lwamayeza abizwa ngokuba zii-antimalarials. Isebenza ngokubulala izinto ezibanga isifo seengcongconi.

IMefloquine iza njengecwecwe lokuthatha ngomlomo. Ngamaxesha onke thatha i-mefloquine enokutya (ngokukhethekileyo esona sidlo sakho siphambili) kunye nee-ounces eziyi-8 (240 milliliters) zamanzi ubuncinci. Ukuba uthatha i-mefloquine ukuthintela isifo seengcongconi, uya kuyithatha kube kanye ngeveki (ngemini enye ngeveki). Uya kuqalisa unyango iiveki ezi-1 ukuya kwezi-3 ngaphambi kokuba uye kwindawo apho isifo seengcongconi sixhaphakile kwaye kufuneka uqhubeke nonyango iiveki ezi-4 emva kokuba ubuyile kuloo ndawo. Ukuba uthatha i-mefloquine ukunyanga isifo seengcongconi, ugqirha wakho uya kukuxelela ngokuthe ngqo ukuba kufuneka usithathe kangaphi. Abantwana banokuthatha amayeza amancinci kodwa aqhelekileyo e-mefloquine. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-mefloquine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Amacwecwe anokuginywa aphele okanye atyunyuzwe kwaye axutywe namanzi, ubisi, okanye esinye isiselo.

Ukuba uthatha i-mefloquine ukunyanga isifo seengcongconi, unokuhlanza kwakamsinya emva kokuba uthathe amayeza. Ukuba uhlanza ngaphantsi kwemizuzu engama-30 emva kokuba uthathe i-mefloquine, kuya kufuneka uthathe elinye idosi epheleleyo ye-mefloquine. Ukuba uyagabha imizuzu engama-30 ukuya kwengama-60 emva kokuba uthathe i-mefloquine, kuya kufuneka uthathe esinye isiqingatha sedosi ye-mefloquine. Ukuba uyagabha kwakhona emva kokuthatha idosi eyongezelelweyo, tsalela ugqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-mefloquine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-mefloquine, i-quinidine (i-Quinadex), i-quinine (i-Qualaquin), nawaphi na amanye amayeza, okanye ezinye izithako ezikwiipilisi ze-mefloquine.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner'); i-antidepressants efana ne-amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), kunye nepritriprine Utywala); antihistamines; ii-calcium channel blocker ezinje nge-amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine , Kunye neverapamil (Calan, Isoptin, Verelan); ii-beta blockers ezinje nge-atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), kunye nepropranolol (Inderal); chloroquine (Aralen); amayeza eswekile, ukugula ngengqondo, ukuxhuzula kunye nesisu esibuhlungu; amayeza okubamba afana ne-carbamazepine (Tegretol), phenobarbital (Luminal), phenytoin (Dilantin), okanye i-valproic acid (Depakene); kunye nerifampin (Rifadin, Rimactane, eRifamate, eRifater). Xelela ugqirha wakho okanye usokhemesti ukuba uthatha la mayeza alandelayo okanye uyekile ukuwathatha kwiiveki ezili-15 ezidlulileyo: i-halofantrine (iHalfan; ayisasebenzi e-United States) okanye i-ketoconazole (Nizoral). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha wanayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye enye yezi zinto zilandelayo: ithuba le-QT elide (ingxaki yentliziyo enqabileyo enokubangela ukubetha kwentliziyo ngokungagunyaziswanga, ukuphelelwa ngamandla, okanye ukufa ngesiquphe), ianemia ( inani elisezantsi kuneliqhelekileyo leeseli ezibomvu zegazi), okanye iliso, isibindi okanye isifo sentliziyo.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa, okanye uncancisa. Kuya kufuneka usebenzise ulawulo lokuzalwa ngelixa uthatha i-mefloquine kunye neenyanga ezi-3 emva kokuyeka ukuyithatha. Ukuba ukhulelwa ngelixa uthatha i-mefloquine, tsalela ugqirha wakho.
• Kuya kufuneka uyazi ukuba i-mefloquine inokukwenza wozele kwaye ube nesiyezi. Ezi mpawu zinokuqhubeka okwethutyana emva kokuba uyeke ukuthatha i-mefloquine. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• Kuya kufuneka uyazi ukuba i-mefloquine iyawunciphisa umngcipheko wokusuleleka sisifo seengcongconi kodwa ayiqinisekisi ukuba awuzukusulelwa. Usafuna ukuzikhusela xa ulunywa yingcongconi ngokunxiba imikhono emide neebhulukhwe ezinde kwaye usebenzise into yokugxotha iingcongconi kunye nenethi yebhedi ngelixa ukwindawo apho isifo seengcongconi sixhaphakile.
• Kuya kufuneka uyazi ukuba iimpawu zokuqala ze-malaria ngumkhuhlane, ukugodola, iintlungu zemisipha kunye nentloko. Ukuba uthatha i-mefloquine yokuthintela isifo seengcongconi, tsalela umnxeba kwangoko ukuba ukhula kwezi mpawu. Qiniseka ukuba uxelela ugqirha wakho ukuba kungenzeka ukuba ukhe wafunyanwa sisifo seengcongconi.
• Kuya kufuneka ucwangcise ukuba uza kwenza ntoni xa unokuba neziphumo ebezingalindelekanga ezivela kwi-mefloquine kwaye kufuneka uyeke ukuthatha amayeza, ngakumbi ukuba awukufuphi kugqirha okanye kwikhemesti. Kuya kufuneka ufumane elinye iyeza lokukhusela kwisifo seengcongconi. Ukuba alikho elinye iyeza elikhoyo, kuyakufuneka uhambe kuloo ndawo ixhaphakileyo imalariya, emva koko ufumane elinye iyeza lokukhusela kwisifo seengcongconi.
• ukuba uthatha i-mefloquine ukunyanga isifo seengcongconi, iimpawu zakho kufuneka ziphuculwe kwisithuba seeyure ezingama-48 ukuya kwezingama-72 emva kokuba ulugqibile unyango lwakho. Biza ugqirha wakho ukuba iimpawu zakho aziphuculanga emva kweli xesha.
• awunalo ugonyo (ukudubula) ngaphandle kokuthetha nogqirha wakho. Ugqirha wakho unokufuna ukuba ulugqibe lonke ugonyo lwakho iintsuku ezi-3 ngaphambi kokuba uqale ukuthatha i-mefloquine.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Mefloquine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ifiva
• urhudo
• iintlungu kwicala lasekunene lesisu sakho
• Ukuphelelwa ngumdla wokutya
• iintlungu zemisipha
• intloko ebuhlungu
• ukozela
• ukwanda kokubila

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba unazo naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye EZIQHELEKILEYO, tsalela umnxeba kwangoko:

• ukurhawuzelela iminwe okanye iinzwane
• ubunzima bokuhamba
• intshukumo ekhanyayo emathunjini
• umchamo omnyama ngombala
• ubumthubi besikhumba sakho okanye umbala omhlophe wamehlo akho
• ukurhawuzelela
• ukushukuma kweengalo okanye imilenze ongakwaziyo ukuyilawula
• utshintsho kumbono
• ubuthathaka bemisipha
• ukuqhawukelwa ngumphefumlo
• iintlungu zesifuba
• uloyiko
• irhashalala

I-Mefloquine inokubangela ezinye iziphumo ebezingalindelekanga. Ungaqhubeka nokufumana iziphumo ebezingalindelekanga ixesha elithile emva kokuba uthathe idosi yakho yokugqibela. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• urhudo
• iintlungu kwicala lasekunene lesisu sakho
• isiyezi
• ukulahleka kwemali eseleyo
• ubunzima bokuwa okanye ukulala
• amaphupha angaqhelekanga
• ukurhawuzelela iminwe okanye iinzwane
• ubunzima bokuhamba
• ukuxhuzula
• utshintsho kwimpilo yengqondo

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Lariam^®¶

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.