Inaliti ye-Apomorphine

Umxholo

• Ngaphambi kokusebenzisa inaliti yeapomorphine,
• Inaliti ye-apomorphine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti ye-Apomorphine isetyenziselwa ukunyanga iziqwengana (amaxesha obunzima bokuhamba, ukuhamba, kunye nokuthetha okunokwenzeka njengoko amayeza ephela okanye engahleliwe) kubantu abanesifo seParkinson esihamba phambili (PD; ukuphazamiseka kwenkqubo yemithambo-luvo ebangela ubunzima ngokuhamba, ukulawula izihlunu, kunye nokulingana) abathatha amanye amayeza kwimeko yabo. Inaliti ye-Apomorphine ikwiklasi yamayeza abizwa ngokuba yi-dopamine agonists. Isebenza ngokusebenza endaweni ye-dopamine, into yendalo eveliswe kwingqondo efunekayo ukulawula ukuhamba.

I-Apomorphine iza njengesisombululo sokujova (ngaphantsi nje kwesikhumba). I-Apomorphine ihlala itofwe xa ifuneka, ngokwemiyalelo kagqirha wakho. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti yeapomorphine ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Sukusebenzisa idosi yesibini yenaliti yeapomorphine kunyango lwesiqwengana "sokucima". Lindela ubuncinci iiyure ezingama-2 phakathi kwamayeza.

Ugqirha wakho uya kukunika elinye iyeza elibizwa ngokuba yi-trimethobenzamide (Tigan) oza kulithatha xa uqala ukusebenzisa inaliti ye-apomorphine. Eli yeza liza kunceda ukunciphisa amathuba okuphuhlisa isicaphucaphu kunye nokugabha ngelixa usebenzisa inaliti ye-apomorphine, ngakumbi ngexesha lokuqala lonyango. Ugqirha wakho uya kukuxelela ukuba uqale ukuthatha i-trimethobenzamide kwiintsuku ezimbalwa ngaphambi kokuba uqale ukusebenzisa inaliti ye-apomorphine, kwaye uqhubeke uyithatha ukuya kuthi ga kwiinyanga ezimbini. Kuya kufuneka uyazi ukuba ukuthatha i-trimethobenzamide kunye nenaliti ye-apomorphine kungonyusa umngcipheko wozela, isiyezi kunye nokuwa. Nangona kunjalo, ungayeki ukuthatha i-trimethobenzamide ngaphandle kokuqala uthethe nogqirha wakho.

Ugqirha wakho uya kukuqala ngedosi esezantsi yenaliti ye-apomorphine kwaye ngokuthe ngcembe ayonyuse idosi yakho, hayi ngaphezulu kwesinye kanye kwiintsuku ezimbalwa. Buza ugqirha wakho ukuba wenzeni ukuba awusebenzisi inaliti yeapomorphine ngaphezulu kweveki enye. Ugqirha wakho uya kuthi akuxelele ukuba uqalise njani la mayeza usebenzisa idosi esezantsi kwaye unyuse ngokuthe ngcembe idosi yakho.

Isisombululo se-Apomorphine siza kwikhatriji yeglasi ukuba siyisebenzise ngepeni yenaliti. Ezinye iinaliti zibonelelwa ngosiba lwakho kunye neenaliti ezongezelelweyo zithengiswa zodwa. Buza ugqirha wakho okanye usokhemesti ukuba unemibuzo malunga nohlobo lwenaliti oyifunayo. Soloko usebenzisa inaliti entsha engenazintsholongwane ngenaliti nganye. Ungaze uphinde usebenzise inaliti, kwaye ungaze uvumele inaliti ichukumise nakweyiphi na indawo ngaphandle kwendawo oza kulifaka kuyo iyeza. Ungaze ugcine okanye uphathe ipeni yenaliti ngenaliti eqhotyoshelweyo. Lahla iinaliti ezisetyenzisiweyo kwisikhongozeli esinganyangekiyo ukuze kungabikho kufikelela ebantwaneni. Thetha nogqirha wakho okanye usokhemesti malunga nendlela yokulahla isikhongozeli esinganyangekiyo.

Uya kufumana idosi yakho yokuqala yenaliti ye-apomorphine kwiofisi yezonyango apho ugqirha wakho anokujonga imeko yakho ngokusondeleyo. Emva koko, ugqirha wakho angakuxelela ukuba ungatofa i-apomorphine ngokwakho okanye umhlobo okanye isalamane senze inaliti. Ngaphambi kokuba usebenzise inaliti ye-apomorphine ngokwakho okokuqala, funda imiyalelo ebhaliweyo eza nayo. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani.

Qiniseka ukuba uyazi ukuba ngawaphi amanani asepenjini yenaliti abonisa idosi yakho. Ugqirha wakho usenokuba ukuxelele ukuba zingaphi iimiligram ekufuneka uzisebenzisile, kodwa usiba lubhalwe ngeemililitha. Buza ugqirha wakho okanye usokhemesti ukuba awuqinisekanga ukuba ungayifumana njani idosi yakho usiba lwenaliti.

Ipeni yokufaka isitofu se-apomorphine yenzelwe ukusetyenziswa ngumntu omnye. Musa ukwabelana ngosiba lwakho nabani na.

Lumka ungafumani inaliti yeapomorphine kulusu lwakho okanye emehlweni akho. Ukuba inaliti yeapomorphine ingena eluswini okanye emehlweni akho, kwangoko hlamba isikhumba sakho okanye uhlambe amehlo akho ngamanzi abandayo.

Unokujova i-apomorphine kwindawo yakho yesisu, engalweni ephezulu, okanye kumlenze wangasentla. Musa ukujova emthanjeni okanye kwindawo apho ulusu lubuhlungu, lubomvu, luchotshoziwe, lunezikrobo, lusulelekile, okanye aluqhelekanga nangayiphi na indlela. Sebenzisa indawo eyahlukileyo yenaliti nganye, ukhetha phakathi kweendawo oxelelwe ukuba uzisebenzise. Gcina irekhodi yomhla kunye nendawo yenaliti nganye. Sukusebenzisa indawo enye amaxesha amabini elandelelana.

Soloko ujonga isisombululo sakho se-apomorphine ngaphambi kokuba uyitofe. Kufuneka icace, ingenambala, kwaye ingenasuntswana. Sukusebenzisa i-apomorphine ukuba kusibekele, luhlaza, iqulethe amasuntswana, okanye ukuba umhla wokuphelelwa kwebhokisi udlulile.

Gcina irekhodi yimalini yenaliti yeapomorphine oyisebenzisayo ngalo lonke ixesha ufumana inaliti ukuze wazi ukuba uyitshintsha nini iCartridge yeyeza.

Unokucoca ipeni yakho ye-apomorphine injector pen kunye nelaphu elimanzi njengoko kufuneka. Ungaze usebenzise isibulali-zintsholongwane esomeleleyo okanye uhlambe usiba lwakho phantsi kwamanzi abalekayo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti yeapomorphine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-apomorphine, nawaphi na amanye amayeza, isulfite, okanye ezinye izithako kwiinaliti yeapomorphine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-alosetron (Lotronex), dolasetron (Anzemet), granisetron (Sancuso), ondansetron (Zofran), okanye palonosetron (Aloxi). Ugqirha wakho uya kuthi kuwe ungasebenzisi inaliti yeapomorphine ukuba uthatha elinye lala mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ukwaliwa, ukukhohlela kunye namayeza abandayo; amiodarone (Nexterone, iPacerone); iziyobisi; antihistamines; chlorpromazine; iDisopyramide (iNorpace); dofetilide (iTikosyn); i-erythromycin (i-EES); haloperidol (iHaldol); amayeza okunyanga ukugula ngengqondo, isisu esibuhlungu, isifo sentliziyo, uxinzelelo lwegazi oluphezulu, iintlungu, okanye ukuxhuzula; metoclopramide (Reglan); moxifloxacin (Avelox); izihlunu ezonwabisayo; amanye amayeza esi sifo sikaParkinson; ipimozide (Orap); ukuvelisa; iprochlorperazine (iCompro); ukwazisa quinidine (kwiNuedexta); ukuthomalalisa; sildenafil (Viagra, Revatio); iipilisi zokulala; isotalol (iBetapace); tadalafil (Cialis); izinto zokuthomalalisa; vardenafil (Levitra); okanye iitrate ezifana ne-isosorbide dinitrate (Isordil, eBidil), isosorbide mononitrate (Monoket), okanye nitroglycerin (Nitro-Dur, Nitrostat, others). AmaNitrate eza njengamacwecwe, iilwimi ezincinci (phantsi kolwimi) iipilisi, izitshizi, iipatches, iipasta kunye namafutha okuthambisa. Buza ugqirha wakho ukuba awuqinisekanga ukuba ngaba nawaphi na amayeza akho ane-nitrate. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• Kuya kufuneka uyazi ukuba xa uthatha i-nitroglycerin phantsi kolwimi lwakho ngelixa usebenzisa inaliti ye-apomorphine, uxinzelelo lwegazi lwakho lunokwehla kwaye lubangele isiyezi. Emva kokuthatha iipilisi ze-nitroglycerin phantsi kolwimi lwakho, kuya kufuneka ulale phantsi ubuncinci imizuzu engama-45 kwaye uphephe ukuma ngeli xesha.
• xelela ugqirha wakho ukuba usela utywala okanye ukuba wakhe wanesifo sombefu okanye wakha wanaso; isiyezi; ukuphelelwa amandla; ukubetha kwentliziyo kancinci okanye okungaqhelekanga; uxinzelelo lwegazi oluphantsi; amanqanaba asezantsi e-potassium okanye i-magnesium egazini; isigulo sengqondo; ingxaki yokulala; ukubetha, ukubetha okuncinci, okanye ezinye iingxaki zobuchopho; iintshukumo ezingalawulwayo kunye nokuwa ngesiquphe; okanye intliziyo, isifo, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa inaliti yeapomorphine, tsalela umnxeba ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa inaliti yeapomorphine.
• Kuya kufuneka uyazi ukuba inaliti yeapomorphine inokukwenza wozele. Sukuqhuba imoto, sebenzisa oomatshini, okanye wenze nantoni na enokukubeka emngciphekweni wokonzakala de ube uyazi indlela ekuchaphazela ngayo eli yeza.
• Kuya kufuneka uyazi ukuba ungalala ngequbuliso ngexesha lomsebenzi wakho wemihla ngemihla ngelixa usebenzisa inaliti yeapomorphine. Usenokuziva ukozela ngaphambi kokuba ulale. Ukuba ngequbuliso ulale xa usenza into yemihla ngemihla njengokutya, ukuthetha, okanye ukubukela umabonwakude, tsalela ugqirha wakho. Musa ukuqhuba imoto okanye usebenzise oomatshini de uthethe nogqirha wakho.
• akufuneki usele utywala ngelixa usebenzisa inaliti yeapomorphine. Utywala bunokwenza iziphumo ebezingalindelekanga ezivela kwi-apomorphine injection ngakumbi.
• Kuya kufuneka uyazi ukuba abanye abantu abathathe amayeza anje ngenaliti ye-apomorphine baphuhlise iingxaki zokungcakaza okanye ezinye iindlela ezinamandla zokuziphatha okanye zokuziphatha ezinyanzelekileyo okanye ezingaqhelekanga kubo, ezinje ngeminqweno yesini okanye isimilo. Akukho lwazi lwaneleyo lokuchaza ukuba ingaba abantu baziphuhlisile na ezi ngxaki kuba bathathe amayeza okanye ezinye izizathu. Tsalela umnxeba ugqirha wakho ukuba unomdla wokungcakaza ekunzima ukuwulawula, uneminqweno enzulu, okanye awukwazi ukulawula indlela oziphethe ngayo. Xelela amalungu osapho lwakho ngalo mngcipheko ukuze bakwazi ukubiza ugqirha nokuba awuqondi ukuba ukungcakaza kwakho okanye nayiphi na eminye iminqweno enzulu okanye indlela yokuziphatha engaqhelekanga ibe yingxaki.
• Kuya kufuneka uyazi ukuba inaliti ye-apomorphine inokubangela ukuba nesiyezi, ukuba nekhaphukhaphu, isicaphucaphu, ukubila, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo olele kuyo okanye ohleli kuyo. Oku kuqheleke ngakumbi xa uqala ukusebenzisa inaliti yeapomorphine okanye ukulandela ukonyuka kwethamo. Ukuthintela le ngxaki, phuma ebhedini okanye uvuke kwindawo ohleli kuyo kancinci, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Eli yeza lihlala lisetyenziswa xa kufuneka njalo.

Inaliti ye-apomorphine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• intloko ebuhlungu
• ukuzamla
• impumlo enemifinya
• ubuthathaka
• ingalo, umlenze, okanye iintlungu zomqolo
• intlungu okanye ubunzima ekuchameni
• Ubuhlungu, ubomvu, iintlungu, ukutyumka, ukudumba, okanye ukurhawuzelela kwindawo otofe kuyo iapomorphine

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• irhashalala; imihlathi ukurhawuzelela; ukudumba kobuso, umqala, ulwimi, imilebe, okanye amehlo; ubunzima bokuphefumla nokuginya; ukuphefumla kancinci, ukukhohlela; okanye ukungcungcutheka
• ngokukhawuleza okanye ukubetha kwentliziyo
• iintlungu zesifuba
• ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukugruzuka
• iintshukumo ezingalawulekiyo ngesiquphe
• iwa phantsi
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho), indlela yokuziphatha enoburharha, ukuphazamiseka, ukuziva ngathi abantu bachasene nawe, okanye iingcinga ezingalungelelananga
• ukudakumba
• ifiva
• ukudideka
• ulungiso olubuhlungu olungapheliyo

Ezinye izilwanyana zaselebhu ezanikwa inaliti yeapomorphine zaphuhliswa sisifo samehlo. Ayaziwa ukuba inaliti ye-apomorphine inyusa umngcipheko wesifo samehlo ebantwini. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza.

I-Apomorphine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina la mayeza kwiCartridge engena engenakufikelela ebantwaneni. Yigcine kwityesi yobushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• isiqaqa
• isiyezi
• ukungaboni kakuhle
• ukubetha kwentliziyo kancinci
• indlela yokuziphatha engaqhelekanga
• nemibono
• iintshukumo ezingalawulekiyo ngesiquphe

Gcina lonke ixesha lokudibana nogqirha wakho.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Apokyn^®