I-Peginterferon Alfa-2a Inaliti

Umxholo

• Ngaphambi kokusebenzisa i-peginterferon alfa-2a,
• I-Peginterferon alfa-2a inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye icandelo LOKUKHUSELWA OKUKHETHEKILEYO, tsalela ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Peginterferon alfa-2a inokubangela okanye iyenze mandundu le miba ilandelayo, enokuba mandundu okanye ibangele ukufa: usulelo; ukugula ngengqondo kubandakanya ukudakumba, imo kunye neengxaki zokuziphatha, okanye iingcinga zokuzenzakalisa okanye ukuzibulala; ukuqala ukusebenzisa iziyobisi ezitalatweni kwakhona ukuba wawukhe wazisebenzisa ngaphambili; ukuphazamiseka kweschemic (iimeko apho ukungabikho kwegazi kwindawo efanelekileyo emzimbeni) njenge-angina (iintlungu zesifuba), isifo sentliziyo, ukubetha, okanye isifo sokukrala kwentliziyo (ukudumba kwamathumbu); kunye nokuphazamiseka komzimba (iimeko apho amajoni omzimba ahlasela elinye okanye ngaphezulu amalungu omzimba) anokuchaphazela igazi, amalunga, izintso, isibindi, imiphunga, izihlunu, ulusu, okanye idlala lengqula. Tshela ugqirha wakho ukuba unentsholongwane; okanye ukuba unesifo sokuzimela komzimba; i-atherosclerosis (ukunciphisa imithambo yegazi kwiidipozithi ezinamafutha); umhlaza; iintlungu zesifuba; ukudumba; isifo seswekile; ukuhlaselwa yintliziyo; igazi elonyukayo; cholesterol ephezulu; Intsholongwane kaGawulayo (intsholongwane yokungakhuseleki komzimba) okanye i-AIDS (i-immunodeficiency syndrome) ukubetha kwentliziyo ngokungaqhelekanga; ukugula ngengqondo kubandakanya ukudakumba, ixhala, okanye ukucinga okanye ukuzama ukuzibulala; isifo sesibindi ngaphandle kwe-hepatitis B okanye i-C; okanye isifo sentliziyo, sezintso, semiphunga okanye sedlala. Xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala, okanye ukuba uye wasebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni okanye wasebenzisa kakhulu amayeza kagqirha. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko kugqirha: urhudo olunegazi okanye ukuhamba kwamathumbu; isisu esibuhlungu, ukuthamba okanye ukudumba; iintlungu zesifuba; ukubetha kwentliziyo ngokungaqhelekanga; ubuthathaka; ukulahleka koququzelelo; ukuba ndindisholo; utshintsho kwiimvakalelo zakho okanye kwindlela oziphatha ngayo; ukudakumba; ukucaphuka; ixhala; iingcinga zokuzibulala okanye ukuzenzakalisa; ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho); ukuphazamiseka okanye ukonwaba ngokungaqhelekanga; ukuphulukana nokunxibelelana nenyani; indlela yokuziphatha enengcwangu; ubunzima bokuphefumla; umkhuhlane, ukugodola, ukukhohlela, umqala obuhlungu, okanye ezinye iimpawu zosulelo; ukukhohlela umchamo omthubi okanye opinki; ukutshisa okanye iintlungu xa uchama, okanye uchama rhoqo; ukopha okungaqhelekanga okanye ukugruzuka; umchamo omnyama-mnyama; ukukhanya kwemibala yokuhamba kwamathumbu; ukudinwa kakhulu; ubumthubi besikhumba okanye amehlo; ubuhlungu obukhulu okanye intlungu edibeneyo; okanye ukwanda kwesifo somzimba.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-peginterferon alfa-2a.

Ugqirha wakho kunye nosokhemesti baya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-peginterferon alfa-2a kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokusebenzisa i-peginterferon alfa-2a.

I-Peginterferon alfa-2a isetyenziswa yodwa okanye idityaniswe namanye amayeza ukunyanga usulelo lwe-hepatitis C engapheliyo (ukudumba kwesibindi okubangelwa yintsholongwane) kubantu ababonisa iimpawu zomonakalo wesibindi. I-Peginterferon alfa-2a ikwasetyenziselwa ukunyanga usulelo lwe-hepatitis B engapheliyo (ukudumba kwesibindi okubangelwa yintsholongwane) kubantu ababonisa iimpawu zomonakalo wesibindi. I-Peginterferon alfa-2a ikudidi lwamayeza abizwa ngokuba zii-interferon. I-Peginterferon yindibaniselwano ye-interferon kunye ne-polyethylene glycol, enceda i-interferon ukuba ihlale isebenza emzimbeni wakho ixesha elide. I-Peginterferon isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) okanye i-hepatitis B virus (HBV) emzimbeni. I-Peginterferon alfa-2a ayinakho ukunyanga i-hepatitis C okanye i-hepatitis B okanye ikuthintele ekuphuhliseni iingxaki ze-hepatitis C okanye i-hepatitis B njenge-cirrhosis (scarring) yesibindi, ukusilela kwesibindi, okanye umhlaza wesibindi. I-Peginterferon alfa-2a ayinako ukuthintela ukusasazeka kwe-hepatitis C okanye i-hepatitis B kwabanye abantu.

I-Peginterferon alfa-2a iza njengesisombululo (ulwelo) kwi-vial, isirinji ekhethiweyo, kunye ne-autoinjector enokulahlwa ngenaliti (kumaleko amanqatha nje phantsi kolusu). Ihlala itofwe kanye ngeveki, kwangalo suku lweveki, kwaye ngexesha elifanayo losuku. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-peginterferon alfa-2a ngokuchanekileyo njengoko kuyalelwe. Sukusebenzisa la mayeza ngokungaphezulu okanye ngaphantsi okanye uwasebenzise rhoqo kunokuba umiselwe ngugqirha.

Ugqirha wakho uya kukuqala ngethamo ye-peginterferon alfa-2a. Ugqirha wakho unokunciphisa idosi yakho ukuba unemiphumo emibi yeyeza. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho kwaye ubuze ugqirha wakho okanye usokhemesti ukuba unemibuzo malunga nenqanaba lonyango ekufuneka ulithathile.

Qhubeka nokusebenzisa i-peginterferon alfa-2a nokuba uziva uphilile. Sukuyeka ukusebenzisa i-peginterferon alfa-2a ngaphandle kokuthetha nogqirha wakho.

Sebenzisa kuphela uphawu kunye nohlobo lwe-interferon emiselwe ngugqirha wakho. Sukusebenzisa olunye uhlobo lwe-interferon okanye utshintshe phakathi kwe-peginterferon alfa-2a kwiibhotile, iisirinji ezikhethiweyo, kunye nee-autoinjectors ezilahlayo ngaphandle kokuthetha nogqirha wakho. Ukuba utshintshela kuhlobo okanye uhlobo lwe-interferon eyahlukileyo, idosi yakho inokufuna ukutshintsha.

Ungayijova i-peginterferon alfa-2a ngokwakho okanye umhlobo okanye isizalwane sikunike iinaliti. Ngaphambi kokuba usebenzise i-peginterferon alfa-2a okokuqala, wena kunye nomntu oza kunika inaliti kufuneka nifunde ulwazi lomenzi wesigulana esiza nayo. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani. Ukuba omnye umntu uza kukutofa iyeza, qiniseka ukuba uyayazi indlela yokuphepha iinaliti ngengozi ukunqanda ukusasazeka kwesifo sokudumba kwesibindi.

Ungayifaka i-peginterferon alfa-2a naphina esiswini okanye emathangeni, ngaphandle kwenkaba yakho (iqhosha lesisu) kunye nesinqe. Sebenzisa indawo eyahlukileyo yenaliti nganye. Sukusebenzisa indawo enye yenaliti izihlandlo ezibini zilandelelana. Sukujova i-peginterferon alfa-2a kwindawo apho ulusu lubuhlungu, lubomvu, luchaphazelekile, lunezikrobo, lusulelekile, okanye lungaqhelekanga nangayiphi na indlela.

Ukuba awufumani idosi emiselweyo ngokupheleleyo ngenxa yengxaki (njengokuvuza kwindawo enenaliti), tsalela ugqirha wakho.

Ungaze uphinde usebenzise iisirinji, iinaliti, okanye iingqayi zepeginterferon alfa-2a. Lahla iinaliti kunye neesirinji esele zisetyenzisiwe. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Ngaphambi kokuba usebenzise i-peginterferon alfa-2a, jonga isisombululo kwi-vial, isirinji ekhethiweyo, okanye i-autoinjector ngokusondeleyo. Musa ukungcangcazela iibhotile, iisirinji, okanye ii-autoinjectors eziqukethe i-peginterferon alfa-2a. Iyeza kufuneka licace kwaye lingenazinto zidadayo. Jonga igutyana okanye isirinji ukuqinisekisa ukuba akukho kuvuza kwaye ujonge umhla wokuphelelwa. Sukusisebenzisa isisombululo ukuba siphelelwe lixesha, sibala ibala, sinamafu, siqulathe amasuntswana, okanye sentsimbi evuzayo okanye isirinji. Sebenzisa isisombululo esitsha, kwaye ubonise esonakeleyo okanye esiphelelwe lixesha kugqirha wakho okanye kwikhemesti.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-peginterferon alfa-2a,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-peginterferon alfa-2a, ezinye ii-alpha interferon, nawaphi na amanye amayeza, i-benzyl alcohol, okanye i-polyethylene glycol (i-PEG). Buza ugqirha wakho ukuba awuqinisekanga ukuba iyeza olichasayo alfer interferon.
• xelela ugqirha wakho ukuba wakhe wafumana inaliti ye-interferon alfa yokunyanga usulelo lwe-hepatitis C.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: amayeza athile e-HIV okanye i-AIDS anje nge-abacavir (Ziagen, e-Epzicom, e-Trizivir), didanosine (ddI okanye Videx), emtricitabine (Emtriva, eTruvada), lamivudine (Epivir, e Combivir, e-Epzicom, e-Trizivir), e-stavudine (e-Zerit), e-tenofovir (e-Viread, e-Truvada), e-zalcitabine (HIVID), nase-zidovudine (Retrovir, e-Combivir, e-Trizivir); imethadone (iDolophine, iMethadose); mexiletine (Mexitil); naproxen (Aleve, Anaprox, Naprosyn, nabanye); iriluzole (Rilutek); itacrine (iCognex); telbivudine (Tyzeka); kunye ne-theophylline (TheoDur, abanye). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-peginterferon alfa-2a, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho okanye usokhemesti ukuba ukhe wafakelwa ilungu lomzimba (uqhaqho ukubuyisela ilungu emzimbeni). Xelela ugqirha wakho ukuba ukhe wakha wanayo nayiphi na kwezi meko ichazwe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye nakwezinye ezi zinto zilandelayo: ianemia (iiseli ezibomvu zegazi azizisi ioksijini eyaneleyo kwamanye amalungu omzimba), okanye iingxaki ngamehlo akho okanye injeke.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa okanye ukuncancisa. I-Peginterferon alfa-2a inokulimaza umbungu okanye ikwenze uphulukane nesisu (ulahlekelwe ngumntwana). Thetha nogqirha wakho malunga nokusebenzisa ulawulo lokuzalwa ngelixa uthatha la mayeza. Akufanele uncelise ngelixa uthatha la mayeza.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-peginterferon alfa-2a.
• Kuya kufuneka uyazi ukuba i-peginterferon alfa-2a inokukwenza ube nesiyezi, udideke, okanye wozele. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• ungaseli utywala ngelixa uthatha i-peginterferon alfa-2a. Utywala bunokusenza mandundu isifo sakho sesibindi.
• Kuya kufuneka uyazi ukuba unokufumana iimpawu ezinje ngomkhuhlane njengentloko, umkhuhlane, ukugodola, ukudinwa, iintlungu zemisipha, kunye nentlungu edibeneyo ngexesha lonyango lwakho nge-peginterferon alfa-2a. Ukuba ezi mpawu ziyakhathaza, buza ugqirha wakho ukuba kufuneka uthathe i-counter-the-counter pain kunye ne-fever reducer ngaphambi kokuba utofe idosi nganye ye-peginterferon alfa-2a. Unokufuna ukutofa i-peginterferon alfa-2a ngexesha lokulala ukuze ulale ngeempawu.

Sela amanzi amaninzi ngelixa uthatha eli yeza.

Ukuba ukhumbula idosi ephosiweyo engekho ngaphezulu kweentsuku ezi-2 emva kokuba ubucwangciselwe ukuyifaka, ngenisa idosi ephosiweyo kwakamsinya nje ukuba uyikhumbule. Emva koko jofa idosi yakho elandelayo kusuku olucwangciswe rhoqo kwiveki elandelayo. Ukuba ngaphezulu kweentsuku ezi-2 zidlulile ukusukela ngala mhla wawucwangciselwe ukutofa amayeza, buza ugqirha wakho okanye usokhemesti into ekufuneka uyenzile. Sukusebenzisa idosi ephindwe kabini okanye usebenzise ngaphezulu kwedosi enye kwiveki e-1 ukwenza idosi ephosiweyo.

I-Peginterferon alfa-2a inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukugruzuka, iintlungu, ukuba bomvu, ukudumba, okanye ukucaphuka kwindawo otofa kuyo i-peginterferon alfa-2a
• isisu esimoshakele
• ukugabha
• isilungulela
• umlomo owomileyo
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• urhudo
• ulusu olomileyo okanye olurhawuzayo
• ukulahleka kweenwele
• ubunzima bokulala okanye ukulala
• ukudinwa
• ubuthathaka
• ubunzima bokugxila okanye ukukhumbula
• ukubila
• isiyezi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye icandelo LOKUKHUSELWA OKUKHETHEKILEYO, tsalela ugqirha wakho ngokukhawuleza:

• ukungaboni kakuhle, utshintsho lombono, okanye ukulahleka kombono
• iintlungu ezisezantsi
• irhashalala
• urhwebo
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• kunzima ukugwinya
• ukudinwa

I-Peginterferon alfa-2a inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kwifriji, kodwa ungayiginyi. Sukushiya i-peginterferon alfa-2a ngaphandle kwefriji ngaphezulu kweeyure ezingama-24 (usuku olu-1). Gcina i-peginterferon alfa-2a kude nokukhanya.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Ukuba ixhoba alizange liwe, tsalela umnxeba ugqirha omisele la mayeza. Ugqirha unokufuna uku-odola uvavanyo lwelebhu.

Iimpawu libanda kungaquka oku kulandelayo:

• ukudinwa
• ukopha okungaqhelekanga okanye ukugruzuka
• umkhuhlane, umqala obuhlungu, Ukugodola, ukukhohlela, okanye ezinye iimpawu zosulelo

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Pegasys^®