Ingcebiso

Umxholo

• Ngaphambi kokuba uthathe i-tipranavir,
• I-Tipranavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

I-Tipranavir (ethathwe nge-ritonavir [Norvir]) inokubangela ukopha kwingqondo. Le meko ingasongela ubomi. Tshela ugqirha wakho ukuba usandula ukwenza utyando, okanye ukuba wenzakele nangayiphi na indlela. Kwakhona xelela ugqirha wakho ukuba unengxaki yokopha efana nehemophilia (imeko apho igazi lingagqumi ngesiqhelo). Xelela ugqirha wakho kunye nosokhemesti ukuba uthatha nawaphi na amayeza alandelayo: ), eptifibatide (Integrilin), heparin, nonsteroidal anti-inflammatory drug (ibuprofen, naproxen), prasugrel (Effient), ticlopidine, okanye tirofiban (Aggrastat). Kuya kufuneka uxelele ugqirha wakho kunye nosokhemesti ukuba uthatha ivithamin E, ngaphandle kwesixa esiqulathwe kwimultivitamin yemihla ngemihla. Ukuba ufuna ukufumana unyango olungxamisekileyo nangasiphi na isizathu, qiniseka ukuxelela bonke oogqirha abakunyangayo ukuba uthatha i-tipranavir. Biza ugqirha wakho ngokukhawuleza ukuba ufumana ukutyumka okungaqhelekanga okanye ukopha ngexesha lonyango lwakho nge-tipranavir.

I-Tipranavir (ethathwe nge-ritonavir [Norvir]) inokubangela ukonakala kwesibindi okunokubusongela ubomi. Tshela ugqirha wakho ukuba ukhe wanesifo sokudumba kwesibindi (ukudumba kwesibindi okubangelwa yintsholongwane), nasiphi na esinye isifo sesibindi, okanye ukuba uyasela okanye usele utywala. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-tipranavir kwaye ubize ugqirha ngoko nangoko: ukudinwa; ubuthathaka; iimpawu ezifana nomkhuhlane; ukuphelelwa ngumdla wokutya; isicaphucaphu; ukugabha; iintlungu, iintlungu, ukudumba, okanye ubuntununtunu kwicala lasekunene ngezantsi kweembambo zakho; ubumthubi besikhumba okanye amehlo; umchamo omnyama (onetayi); okanye ukuhamba kwamathumbu amhlophe.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-tipranavir.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-tipranavir.

I-Tipranavir isetyenziswa ne-ritonavir (i-Norvir) kunye namanye amayeza ukunyanga usulelo lwe-HIV (i-HIV). I-Tipranavir ikudidi lwamayeza abizwa ngokuba zii-protease inhibitors. Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-tipranavir ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezomeleleyo okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa intsholongwane kagawulayo kwabanye abantu.

I-Tipranavir iza njengephilisi kunye nesisombululo somlomo (ulwelo) ukuba sithathwe ngomlomo. Ukuba i-tipranavir ithathwa ngee-capsule ze-ritonavir okanye isisombululo, ihlala iphindwe kabini ngemini okanye ngaphandle kokutya. Ukuba i-tipranavir ithathwa ngamacwecwe e-ritonavir, ihlala idla kabini ngemini ngokutya. Thatha i-tipranavir kunye ne-ritonavir kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-tipranavir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Musa ukuthatha i-tipranavir ngaphandle kwe-ritonavir.

Ginya zonke iifomsile; sukuzihlafuna okanye uzityumze. Ukuba awukwazi ukugwinya iicapsule, xelela ugqirha wakho okanye usokhemesti.

I-Tipranavir iyanceda ukulawula usulelo lwe-HIV kodwa ayiyinyangi. Qhubeka nokuthatha i-tipranavir nokuba uziva uphilile. Sukuyeka ukuthatha i-tipranavir ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukuthatha i-tipranavir okanye ukweqa iidosi, imeko yakho kunokuba nzima ukunyanga. Xa unikezelo lwakho lwe-tipranavir luqala ukuba phantsi, fumana ngakumbi kugqirha wakho okanye kwikhemesti.

Buza ugqirha wakho okanye usokhemesti ikopi yolwazi lomenzi wesigulana. Funda olu lwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-tipranavir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-tipranavir, i-ritonavir (i-Norvir, e-Kaletra), amayeza e-sulfa, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwipilisi ze-tipranavir okanye isisombululo. Buza usokhemesti wakho ukuba awuqinisekanga ukuba iyeza olichasayo lelonyango lwe-sulfa. Buza usokhemesti wakho uluhlu lwezinto ezikwiipilisi zeethipranavir okanye isisombululo.
• xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo okanye iimveliso zamayeza: alfuzosin (Uroxatral); i-cisapride (iPropulsid) (ayisafumaneki e-U.S.); amayeza ergot kwimigraines efana ne-dihydroergotamine (i-DHE 45, iMigranal), i-ergoloid mesylate (iHydergine), i-ergotamine (i-Ergomar, eCafergot, eMigergot, abanye), okanye i-methylergonovine (Methergine); amayeza athile okubetha kwentliziyo okungaqhelekanga kubandakanya i-amiodarone (Nexterone, Pacerone), flecainide, propafenone (Rythmol), okanye iquinidine (eNuedexta); i-lovastatin (Altoprev), i-lurasidone (iLatuda); midazolam ngomlomo; ipimozide (Orap); irifampin (Rifadin, Rimactane, eRifamate, eRifater); sildenafil (Revatio) kunyango lwexinzelelo lwe-pulmonary arterial hypertension, i-simvastatin (iZocor, eVytorin); I-wort yaseSt. kunye netriazolam (Halcion). Ugqirha wakho uya kukuxelela ukuba ungathathi i-tipranavir ukuba uthatha elinye okanye ngaphezulu kula mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: amayeza okubola afana ne-fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), okanye voriconazole (Vfend); i-boceprevir (ayisafumaneki e-US; iVictrelis); i-bosentan (iTracleer); iicalcium-channel blocker ezinjenge diltiazem (Cardizem, Cartia, Diltzac, Taztia, Tiazac, abanye), felodipine, nicardipine, nisoldipine (Sular), okanye verapamil (Calan, Covera, Verelan, others); iyeza elinciphisa i-cholesterol ('statins') njenge-atorvastatin (Lipitor, eCaduet) kunye ne-rosuvastatin (Crestor); i-clarithromycin (i-Biaxin, kwi-Prevpac); icolchicine (Colcrys, Mitigare, kwiCol-Probenecid); desipramine (Norpramin); disulfiram (Antabuse); Unyango lwe-estrogen yokutshintsha; i-fluticasone (Flonase, Flovent, eAdvair, eDymista); ii-immunosuppressants ezinje ngecyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), okanye tacrolimus (Astagraf, Envarsus XR, Prograf, abanye); amayeza eswekile efana ne-glimepiride (Amaryl, kwi-Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, abanye), pioglitazone (Actos, eActoplus Met, eDuetact, eOseni), repaglinide (Prandin, e Prandimet) okanye i-tolbutamide; amayeza athile e-erectile dysfunction kubandakanya i-sildenafil (Viagra), tadalafil (Adcirca, Cialis), okanye vardenafil (Levitra, Staxyn); amayeza athile okubanjwa kubandakanya i-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, phenytoin (Dilantin, Phenytek), kunye ne-valproic acid (Depakene); amanye amayeza e-HIV kubandakanya i-abacavir (iZiagen, e-Epzicom, eTrizivir), atazanavir (Reyataz, e-Evotaz), dolutegravir (Tivicay, e-Juluca), enfuvirtide (Fuzeon); i-etravirine (ukungakhathali); fosamprenavir (Lexiva), lopinavir (eKaletra), raltegravir (Isentress), kunye ne-saquinavir (Invirase); meperidine (iDemerol); imethadone (iDolophine, iMethadose); i-metronidazole (iFlagyl, ePylera); omeprazole (Prilosec, eZegerid); iquetiapine (iSeroquel); irifabutin (Mycobutin); isalmeterol (iSerevent, eAdvair); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo efana ne-fluoxetine (Prozac, Sarafem, Selfemra, kwi-Symbyax), i-paroxetine (Brisdelle, Paxil, Pexeva), okanye i-sertraline (iZoloft); I-telaprevir (ayisafumaneki e-US; Incivek); kunye ne-trazodone. Amanye amayeza amaninzi anokusebenzisana ne-tipranavir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Qiniseka ukuba uthetha nogqirha wakho okanye usokhemesti ngaphambi kokuba uqale ukuthatha nawaphi na amayeza amatsha ngexesha lonyango lwakho nge-tipranavir. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha i-didanosine (Videx), yithathe iiyure ezi-2 ngaphambi okanye iiyure ezi-2 emva kokuba uthathe i-tipranavir.
• ukuba uthatha ii-antacids, thatha iyure enye ngaphambi okanye kwiiyure ezimbini emva kokuba uthathe i-tipranavir.
• xelela ugqirha wakho ukuba ukhe unesifo seswekile okanye uneswekile ephezulu yegazi; i-cholesterol yegazi ephezulu okanye i-triglycerides (amafutha egazi); okanye usulelo oluza ludlule njengesifo sephepha (TB), cytomegalovirus (CMV), herpes, Mycobacterium avium, shingles, okanye pneumonia.
• Kuya kufuneka uyazi ukuba abanye abantu abanesifo seswekile baya besiba mandundu kwisifo seswekile ngelixa bethatha i-tipranavir. Ukuba unesifo seswekile, kubalulekile ukuba ujonge ngononophelo iswekile yegazi ngelixa uthatha i-tipranavir kwaye ubize ugqirha wakho ukuba iswekile yegazi lakho iba nzima ukulawula. Ugqirha wakho unokufuna ukutshintsha iyeza leswekile okanye amisele amayeza amatsha ukulawula iswekile esegazini.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-tipranavir, tsalela ugqirha wakho. Musa ukuncancisa xa wosulelwe yi-HIV okanye uthatha i-tipranavir.
• Kuya kufuneka uyazi ukuba i-tipranavir inokunciphisa ukusebenza kwezicwangcisi zehomoni (iipilisi zokulawula ukuzalwa, iipatches, iiringi kunye nenaliti). Kuya kufuneka usebenzise enye indlela yokuthintela ukukhulelwa ukuthintela ukukhulelwa ngelixa uthatha i-tipranavir. Thetha nogqirha wakho ngezinye iindlela zokuthintela ukukhulelwa ngelixa uthatha eli yeza.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-tipranavir.
• cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. I-Tipranavir inokwenza ulusu lwakho lubuthathaka kwilanga.
• Kuya kufuneka uyazi ukuba amanqatha omzimba wakho anganyuka okanye afudukele kwiindawo ezahlukeneyo zomzimba wakho ezinjengomqolo wentamo yakho namagxa angaphezulu (’inyathi unqonqo), isisu, namabele. Umzimba wakho ungalahla amanqatha ezingalweni, emilenzeni, ebusweni nasezimpundu. Thetha nogqirha wakho ukuba uphawula naluphi na olu tshintsho kumanqatha akho emzimbeni.
• Kuya kufuneka uyazi ukuba unokufumana i-hyperglycemia (inyuka kwiswekile esegazini lakho) ngelixa uthatha eli yeza, nokuba awukabinaso isifo seswekile. Tshela ugqirha wakho ngokukhawuleza ukuba unayo nayiphi na impawu zilandelayo ngelixa uthatha i-tipranavir: ukoma kakhulu, ukuchama rhoqo, ukulamba kakhulu, umbono ophazamisayo, okanye ubuthathaka. Kubaluleke kakhulu ukubiza ugqirha wakho nje ukuba ube nazo naziphi na ezi mpawu, kuba iswekile ephezulu yegazi enganyangekiyo inokubangela imeko embi ebizwa ngokuba yi ketoacidosis. I-Ketoacidosis inokuba sengozini yobomi ukuba ayinyangwa kwangoko. Iimpawu zeketoacidosis zibandakanya umlomo owomileyo, isicaphucaphu kunye nokugabha, ukuphefumla kancinci, ukuphefumla okunuka iziqhamo kunye nokuncipha kwengqondo.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye ezibaxekileyo nangaliphi na ixesha kunyango lwakho nge-tipranavir, qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo kunye ne-ritonavir ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Tipranavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukuhla ukusinda
• intloko ebuhlungu
• isisu esibuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• umkhuhlane, ukugodola, ukukhohlela, okanye ezinye iimpawu zosulelo
• irhashalala
• ubomvu, ukutshiza, okanye ukucola ulusu
• ukurhawuzelela
• ukuqina komqala
• ukuqhawukelwa ngumphefumlo
• ubuthathaka, ukuba ndindisholo nentlungu, ezandleni nasezinyaweni
• ubunzima bokuphefumla okanye ukugwinya
• intlungu yesihlunu okanye edibeneyo okanye ukuqina

I-Tipranavir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina iibhotile ezingavulwanga zeephilisi ze tipranavir kwifriji. Gcina iibhotile ezivulekileyo zeephilisi ze-tipranavir kubushushu begumbi, kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina isisombululo setipranavir kubushushu begumbi. Musa ukufriji okanye ubambe isisombululo se-tipranavir. Phawula umhla ovula ngayo ibhotile ye-tipranavir kwileyibhile; ukuba iyeza alisetyenziswanga kwiintsuku ezingama-60, lahla amayeza aseleyo.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-tipranavir.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• I-Aptivus^®