Inaliti ye-Abatacept

Umxholo

• Ngaphambi kokusebenzisa i-abatacept,
• I-Abatacept inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

I-Abatacept isetyenziswa yodwa okanye idityaniswe namanye amayeza ukunciphisa iintlungu, ukudumba, ubunzima ngemisebenzi yemihla ngemihla, kunye nomonakalo odibeneyo odalwe sisifo samathambo (imeko apho umzimba uhlasela amalungu ayo ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi) kubantu abadala abangakhange bancedwe ngamanye amayeza. Isetyenziswa sodwa okanye ngokudibeneyo ne-methotrexate (Trexall) ukunyanga i-polyarticular juvenile idiopathic arthritis (PJIA; uhlobo lwesifo samathambo ebuntwaneni esichaphazela amalungu amahlanu okanye nangaphezulu kwiinyanga ezintandathu zokuqala kwimeko, kubangela iintlungu, ukudumba, kunye nelahleko. function) kubantwana abaneminyaka emi-2 ubudala okanye ngaphezulu. I-Abatacept ikwasetyenziswa yodwa okanye ngokudibeneyo namanye amayeza ukunyanga i-psoriatic arthritis (imeko ebangela iintlungu ezidibeneyo kunye nokudumba kunye nezikali kulusu) kubantu abadala. I-Abatacept ikwiklasi yamayeza abizwa ngokuba ziimodyuli zokukhetha iindleko (ii-immunomodulators). Isebenza ngokuthintela umsebenzi wee-T-seli, uhlobo lweseli yomzimba emzimbeni ebangela ukudumba kunye nomonakalo odibeneyo kubantu abane-arthritis.

I-Abatacept iza njengomgubo oza kuxutywa namanzi angenazintsholongwane ukuba anikwe ngaphakathi (emthanjeni) kwaye njengesisombululo (ulwelo) kwisirinji ekhethiweyo okanye isixhobo sokufaka intsholongwane esizakunikwa ngendlela engaphantsi (phantsi kolusu). Ihlala inikwa ngugqirha okanye ngumongikazi kwiofisi kagqirha okanye kwiziko lokhathalelo lwempilo xa unikwe ngaphakathi. Kukwanokunikezelwa kum ngaphantsi ngugqirha okanye umongikazi okanye wena okanye umntu okhathalayo unokuxelelwa ukuba atofe iyeza ngendlela engeyiyo ekhaya. Xa i-abatacept inikwa ngaphakathi ngenaliti ukunyanga i-rheumatoid arthritis okanye i-psoriatic arthritis, ihlala inikwa rhoqo emva kweeveki ezi-2 kwiidosi zokuqala ezi-3 kwaye emva kweeveki ezi-4 ukuba unyango luyaqhubeka. Xa i-abatacept inikwa ngaphakathi ngenaliti ukunyanga i-polyarticular juvenile idiopathic arthritis kubantwana abaneminyaka emi-6 nangaphezulu, ihlala inikwa rhoqo kwiiveki ezimbini kwiidosi zokuqala ezimbini kwaye emva kweeveki ezine ixesha elide lisaqhubeka unyango. Kuya kuthatha malunga nemizuzu engama-30 ukuba ufumane idosi yakho yonke ye-abatacept efakwe ngaphakathi. Xa i-abatacept inikwa ngokunyanga ukunyanga i-rheumatoid arthritis okanye i-psoriatic arthritis kubantu abadala kunye ne-polyarticular juvenile idiopathic arthritis kubantwana abaneminyaka emi-2 nangaphezulu, ihlala inikwa kube kanye ngeveki.

Ukuba uza kutofa inaliti yokuxhela ngokwakho ekhaya okanye umhlobo okanye isalamane sikuthelele amayeza, buza ugqirha wakho akubonise okanye umntu oza kungenza iyeza ukuba angalitofa njani. Wena kunye nomntu oza kutofa iyeza kufuneka ufunde imiyalelo ebhaliweyo yomenzi wokusetyenziswa okuza nonyango.

Ngaphambi kokuba uvule iphakheji enamayeza akho, jonga ukuba uqiniseke ukuba umhla wokuphelelwa oprintwe kwiphakheji awudlulanga. Emva kokuba uvule iphakheji, jonga kufutshane kulwelo olukusirinji. Umbane kufuneka ucace okanye ubutyheli obumbala kwaye akufuneki ubenamasuntswana amakhulu anemibala. Fowunela usokhemesti wakho, ukuba kukho naziphi na iingxaki kwiphakheji okanye kwisirinji. Musa ukutofa amayeza.

Ungayifaka inaliti yesilarha naphina esiswini okanye emathangeni ngaphandle kwenkaba yakho (iqhosha lesisu) kunye nendawo eyi-intshi ezimbini kuyo. Ukuba omnye umntu uya kukujolela iyeza, loo mntu unokulifaka kwindawo engaphandle kwengalo yakho. Sebenzisa indawo eyahlukileyo yenaliti nganye. Sukujova inaliti yokuxhela kwindawo ekuthambekayo, eyonzakeleyo, ebomvu, okanye enzima. Kwakhona, musa ukujova kwiindawo ezinamanxeba okanye ezolula amanqaku.

Susa isirinji ekhethiweyo okanye i-autoinjector ekhethiweyo kwifriji kwaye uyivumele ifudumale kubushushu begumbi kangangemizuzu engama-30 ngaphambi kokuyisebenzisa. Musa ukufudumeza inaliti yokufudumeza emanzini ashushu, kwimicrowave, okanye uyibeke elangeni. Sukususa isiciko senaliti ngelixa uvumela isirinji ekhethiweyo ukuba ifikelele kubushushu begumbi.

Ugqirha wakho uya kukunika uxwebhu lolwazi lwesigulana lomenzi ukuba ulifunde ngaphambi kokuba ufumane idosi nganye yesilarha. Funda ulwazi ngononophelo kwaye ubuze ugqirha wakho nayiphi na imibuzo onayo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-abatacept,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa isifo sokuxhela, nawaphi na amanye amayeza, okanye nasiphi na isithako senaliti yokuxhelwa. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: anakinra (Kineret), adalimumab (Humira), etanercept (Enbrel), kunye ne-infliximab (Remicade). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unentsholongwane naphina emzimbeni, kubandakanya usulelo oluza luphela, njengezilonda ezibandayo, kunye nosulelo olungapheliyo olungapheliyo, okanye ukuba uhlala ufumana naluphi na uhlobo losulelo olufana nosulelo lwesinyi. Xelela ugqirha wakho ukuba ukhe okanye wakha wanaso isifo esinganyangekiyo semiphunga (COPD; iqela lezifo zemiphunga ezibandakanya i-bronchitis engapheliyo kunye ne-emphysema); nasiphi na isifo esichaphazela inkqubo yakho yeemvakalelo, enjenge-multiple sclerosis; Nasiphi na isifo esichaphazela amajoni akho omzimba, anjengomhlaza, intsholongwane (i-HIV), ifunyenwe i-immunodeficiency syndrome (i-AIDS), okanye isifo esihlangeneyo se-immunodeficiency syndrome (SCID). Xelela ugqirha wakho ukuba unesifo sephepha (TB), usulelo lwemiphunga olungenakubangela zimpawu zeminyaka emininzi kwaye ezinokuthi zisasazeke kwamanye amalungu omzimba) okanye ukuba ukhe wakufutshane nomntu onesifo sephepha. . Ugqirha wakho unokukunika uvavanyo lolusu ukuze abone ukuba awosulelwanga sisifo sephepha na. Tshela ugqirha wakho ukuba wakhe wavavanywa ulusu ngesifo sephepha kwixa elidlulileyo.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa i-abatacept, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-abatacept.
• xelela ugqirha wakho ukuba usandula ukufumana okanye ucwangciselwe ukufumana naziphi na izitofu. Akufanele ube nogonyo ngelixa usebenzisa i-abatacept okanye iinyanga ezi-3 emva kwethamo lakho lokugqibela lokubulala ngaphandle kokuthetha nogqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba ufumana i-abatacept nge-intravenia kwaye uphoswa li-aphoyintimenti yokufumana ukumiliselwa kwesilarha, biza ugqirha ngokukhawuleza.

Ukuba ufumana i-abatacept ngokungxama kwaye uphoswa yidosi, cela ugqirha wakho ngeshedyuli entsha yedosi.

I-Abatacept inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• impumlo enemifinya
• umqala obuhkungu
• isicaphucaphu
• isiyezi
• isilungulela
• umqolo obuhlungu
• Intlungu yengalo okanye yomlenze

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• urhwebo
• irhashalala
• ukurhawuzelela
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, okanye umqala
• ubunzima bokuphefumla okanye ukugwinya
• ukuqhawukelwa ngumphefumlo
• umkhuhlane, ukugodola kunye neminye imiqondiso yosulelo
• khohlela owomileyo ongapheliyo
• ukuhla ukusinda
• ukubila ebusuku
• Ukuchama rhoqo okanye isidingo sokuchama ngokukhawuleza
• ukutshisa ngexesha lokuchama
• i-cellulitis (obomvu, oshushu, indawo edumbileyo eluswini)

I-Abatacept inokunyusa umngcipheko wokuphuhlisa iintlobo ezithile zomhlaza kubandakanya i-lymphoma (umhlaza oqala kwiiseli ezilwa nosulelo) kunye nomhlaza wolusu. Abantu abanesifo se-rheumatoid arthritis ixesha elide banokuba nomngcipheko omkhulu kunokwesiqhelo wokuphuhlisa le mihlaza nangona bengayisebenzisi i-abatacept. Ugqirha wakho uya kujonga ulusu lwakho kulo naluphi na utshintsho ngexesha lonyango lwakho. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza.

I-Abatacept inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Gcina iisirinji ezizalisiweyo kunye nee-autoinjectors kwikhatoni yoqobo engenayo ukuyikhusela ekukhanyeni nasekufikeleleni ebantwaneni. Gcina iisirinji ezizalisiweyo okanye ii-autoinjectors kwifriji kwaye ungabandi.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwinaliti yokuxhela.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba usebenzisa inaliti ye-abatacept.

Ukuba unesifo seswekile kwaye ufumana i-abatacept ngaphakathi, inaliti yokuxhela inokunika ukufundwa kweglucose ephezulu ngobuxoki ngomhla wokufakwa kwakho. Thetha nogqirha wakho okanye usokhemesti malunga nokuvavanywa kokuvavanywa kweglucose yegazi ngexesha lokusebenzisa unyango.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Orencia^®