Inaliti yeBevacizumab

Umxholo

• Iimveliso zenaliti zeBevacizumab ziyasetyenziswa
• Ngaphambi kokufumana imveliso yenaliti ye-bevacizumab,
• Iimveliso zenaliti ye-Bevacizumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Bevacizumab, inaliti ye-bevacizumab-awwb, kunye nenaliti ye-bevacizumab-bvzr ngamayeza e-biologic (amayeza enziwe kwizinto eziphilayo). Inaliti ye-Biosimilar bevacizumab-awwb kunye ne-bevacizumab-bvzr inaliti ifana kakhulu nenaliti ye-bevacizumab kwaye isebenza ngendlela efanayo nenaliti ye-bevacizumab emzimbeni. Ke ngoko, igama elithi bevacizumab injection products liza kusetyenziswa ukumela la mayeza kule ngxoxo.

Iimveliso zenaliti zeBevacizumab ziyasetyenziswa

• ngokudibeneyo namanye amayeza e-chemotherapy ukunyanga umhlaza wekholoni (amathumbu amakhulu) okanye i-rectum ethe yasasazeka kwamanye amalungu omzimba;
• ngokudibeneyo namanye amayeza e-chemotherapy ukunyanga iintlobo ezithile zomhlaza wemiphunga osasazeke kwizicubu ezikufuphi okanye amanye amalungu omzimba, angenakususwa ngotyando, okanye abuye emva konyango ngamanye amayeza e-chemotherapy;
• ukunyanga i-glioblastoma (uhlobo oluthile lomhlaza wobuchopho obunomhlaza) olungakhange luphuculwe okanye lubuyile emva konyango ngamanye amayeza;
• ngokudibeneyo ne-interferon alfa yokunyanga umhlaza we-renal cell (RCC, uhlobo lomhlaza oqala kwizintso) oluye lwasasazeka kwamanye amalungu omzimba;
• ngokudibeneyo namanye amayeza e-chemotherapy ukunyanga umhlaza womlomo wesibeleko (umhlaza oqala ekuvulekeni kwesibeleko [isibeleko]) esingakhange siphuculwe okanye sibuye emva konyango ngamanye amayeza okanye sisasazeke kwamanye amalungu omzimba;
• ngokudibeneyo namanye amayeza e-chemotherapy ukunyanga iintlobo ezithile ze-ovarian (amalungu okuzala ababhinqileyo apho kwenziwa khona amaqanda), ityhubhu yokuhambisa (ityhubhu ehambisa amaqanda akhululwe ngamaqanda esibelekweni), kunye ne-peritoneal (umaleko wethishu obeka isisu) umhlaza engakhange iphucuke okanye ibuye emva konyango ngamanye amayeza; kwaye
• ngokudibeneyo ne-atezolizumab ukunyanga i-hepatocellular carcinoma (HCC) ethe yasasazeka okanye ayinakususwa ngotyando kubantu abangazange bafumane i-chemotherapy ngaphambili.

Iimveliso zenaliti ye-Bevacizumab ikudidi lwamayeza abizwa ngokuba ziiarhente ze-antiangiogenic. Basebenza ngokunqanda ukwenziwa kwemithambo yegazi ezisa ioksijini kunye nezakhamzimba kumathumba. Oku kunokunciphisa ukukhula kunye nokusasazeka kwamathumba.

Iimveliso zenaliti zeBevacizumab ziza njengesisombululo (ulwelo) ukuhambisa kancinci emthanjeni. Iimveliso zenaliti ye-Bevacizumab zilawulwa ngugqirha okanye umongikazi kwiofisi yezonyango, kwiziko lokumnika, okanye esibhedlele. Iimveliso zenaliti ye-Bevacizumab zihlala zinikwa kube kanye kwiiveki ezi-2 okanye ezi-3. Ishedyuli yakho yokulinganisa iya kuxhomekeka kwimeko onayo, amanye amayeza owasebenzisayo, kunye nendlela ophendula ngayo emzimbeni wakho kunyango.

Kuya kuthatha imizuzu engama-90 ukuba ufumane idosi yakho yokuqala yemveliso yenaliti ye-bevacizumab. Ugqirha okanye umongikazi uya kukujonga ngokusondeleyo ukuze abone ukuba umzimba wakho uphendula njani kwi-bevacizumab. Ukuba awunayo nayiphi na ingxaki enkulu xa ufumana idosi yakho yokuqala yemveliso yenaliti ye-bevacizumab, iya kuthatha imizuzu engama-30 ukuya kwengama-60 ukuba ufumane idosi nganye eseleyo yonyango.

Iimveliso zenaliti ye-Bevacizumab inokubangela iimpendulo ezinzulu ngexesha lokufakwa kweyeza. Ukuba unazo naziphi na kwezi mpawu zilandelayo, xelela ugqirha wakho kwangoko: ubunzima bokuphefumla okanye ukuphefumla kancinci, ukugodola, ukungcangcazela, ukubila, iintloko, iintlungu esifubeni, isiyezi, ukuziva utyhafile, ukugungxula, ukurhawuzelela, irhashalala, okanye umngxunya. Ugqirha wakho unokufuna ukunciphisa ukunyuswa kwakho, okanye ukulibaziseka okanye ukuyeka unyango lwakho xa ufumana ezi zinto okanye ezinye iziphumo.

Inaliti ye-Bevacizumab (Avastin) ngamanye amaxesha isetyenziselwa ukunyanga ukubola okuhambelana nobudala obumanzi (i-AMD; isifo esiqhubekayo samehlo esibangela ukulahleka kwamandla okubona ngokuthe ngqo kwaye sinokwenza kube nzima ngakumbi ukufunda, ukuqhuba, okanye ukwenza ezinye izinto. imisebenzi yemihla ngemihla). Thetha nogqirha wakho malunga nomngcipheko wokusebenzisa i-bevacizumab ukunyanga imeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana imveliso yenaliti ye-bevacizumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-bevacizumab, bevacizumab-awwb, bevacizumab-bvzr, nawaphi na amanye amayeza, okanye nasiphi na isithako semveliso yenaliti ye-bevacizumab.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya ii-anticoagulants (igazi elincinci) njenge-warfarin (Coumadin, Jantoven); kunye ne-sunitinib (Sutent). Xelela ugqirha wakho ukuba uthatha okanye ukuba wakhe wathatha i-anthracycline (uhlobo lwe-chemotherapy olusetyenziselwa umhlaza webele kunye nezinye iintlobo ze-leukemia) ezinjenge-daunorubicin (Cerubidine), doxorubicin, epirubicin (Ellence), okanye idarubicin (Idamycin) . Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba wakhe waphathwa ngonyango lwe-radiation kwicala lasekhohlo lesifuba sakho okanye isinqe; kwaye ukuba ukhe wanalo uxinzelelo oluphezulu lwegazi, ukusilela kwentliziyo, okanye nayiphi na imeko echaphazela intliziyo yakho okanye imithambo yegazi (iityhubhu ezihambisa igazi phakathi kwentliziyo namanye amalungu omzimba). Xelela ugqirha wakho ukuba usandula ukukhohlela igazi.
• Kuya kufuneka uyazi ukuba iimveliso zenaliti ye-bevacizumab inokubangela ukungachumi kwabasetyhini (kunzima ukukhulelwa); Nangona kunjalo, akufuneki ucinge ukuba awungekhe ukhulelwe. Tshela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho ngemveliso yenaliti ye-bevacizumab kwaye ubuncinci iinyanga ezi-6 emva kwedosi yakho yokugqibela.Ukuba ukhulelwa ngelixa usebenzisa imveliso yenaliti ye-bevacizumab, tsalela ugqirha wakho. I-Bevacizumab inokulimaza umbungu kwaye inyuse umngcipheko wokulahleka kokukhulelwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngexesha lonyango lwakho ngemveliso yenaliti ye-bevacizumab kwaye ubuncinci iinyanga ezi-6 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linokubangela ukusilela kwe-ovari. Thetha nogqirha wakho malunga nomngcipheko wokungachumi kwabasetyhini okubangelwa yi-bevacizumab. Thetha nogqirha wakho malunga nomngcipheko wokusebenzisa imveliso ye-bevacizumab.
• xelela ugqirha wakho ukuba usandula kutyandwa okanye ukuba uceba ukwenza utyando, kubandakanya nonyango lwamazinyo. Ukuba ucwangciselwe ukuba utyando, ugqirha wakho uza kuyeka unyango lwakho ngemveliso yenaliti ye-bevacizumab ubuncinci kwiintsuku ezingama-28 ngaphambi kotyando. Ukuba usandula ukwenza utyando, akufuneki ufumane imveliso yenaliti ye-bevacizumab de kube kudlule ubuncinci iintsuku ezingama-28 kwaye de indawo leyo iphiliswe ngokupheleleyo.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphoswa idinga lokufumana idosi yemveliso yenaliti ye-bevacizumab, tsalela ugqirha ngokukhawuleza.

Iimveliso zenaliti ye-Bevacizumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isiyezi
• Ukuphelelwa ngumdla wokutya
• isilungulela
• utshintsho kwisakhono sokungcamla ukutya
• urhudo
• ukuhla ukusinda
• izilonda kulusu okanye emlonyeni
• Ilizwi liyatshintsha
• ukunyuka okanye ukunciphisa iinyembezi
• impumlo egobileyo okanye egobayo
• intlungu yesihlunu okanye edibeneyo
• ingxaki yokulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukuphuma kweempumlo okanye ukopha kwiintsini zakho; ukukhohlela okanye ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi; ukopha okungaqhelekanga okanye ukugruzuka; ukwanda kokuya esikhathini okanye ukopha kwilungu lobufazi; umchamo opinki, obomvu, okanye omnyama; obomvu okanye ukulinda ukuhamba kwamathumbu amnyama; okanye intloko ebuhlungu, isiyezi, okanye ubuthathaka
• kunzima ukugwinya
• intetho ecothayo okanye enzima
• ukudinwa
• ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze
• iintlungu zesifuba
• iintlungu ezingalweni, entanyeni, emhlathini, esiswini, okanye ngasemva
• ukuphefumla kancinci okanye ukuvutha
• ukuxhuzula
• ukudinwa kakhulu
• ukudideka
• utshintsho kumbono okanye ukulahleka kombono
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• ukudumba kobuso, amehlo, isisu, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukuzuza ubunzima obungachazwanga
• umchamo wegwebu
• iintlungu, ukuthamba, ukufudumala, ukuba bomvu, okanye ukudumba emlenzeni omnye kuphela
• ubomvu, ukurhawuzelela, okanye ukwanda kolusu
• isisu esibuhlungu, ukuqhina, isicaphucaphu, ukugabha, ukungcangcazela, okanye umkhuhlane

Iimveliso zenaliti ye-Bevacizumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho. Ugqirha wakho uya kujonga uxinzelelo lwegazi kwaye avavanye umchamo wakho rhoqo ngexesha lonyango lwakho ngemveliso yenaliti ye-bevacizumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Avastin^® (bevacizumab)
• UMvasi^® (bevacizumab-awwb)
• Zirabev^® (bevacizumab-bvzr)