Umbhali: William Ramirez
Umhla Wokudalwa: 20 Eyomsintsi 2021
Hlaziya Umhla: 13 Eyenkanga 2024
Anonim
Role of Gefitinib in EGRF-Mutant Disease
Ividiyo: Role of Gefitinib in EGRF-Mutant Disease

Umxholo

I-Gefitinib isetyenziselwa ukunyanga umhlaza wamaphaphu ongekho mncinci osasazeke kwamanye amalungu omzimba kubantu abaneentlobo ezithile zamathumba. UGefitinib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo sento ethile yendalo enokubakho enokufuneka ukunceda iiseli zomhlaza zande.

IGefitinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye ngemini. Thatha i-gefitinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-gefitinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba awukwazi ukugwinya iipilisi, unokuzinyibilikisa emanzini. Beka ithebhulethi enye kwii-ounces ezi-4 ukuya kwezi-8 (120 ukuya ku-240 mL) zamanzi okusela angenanto. Gcoba ngepuni malunga nemizuzu engama-15 de ithebhulethi ichitheke. Sela lo mxube ngoko nangoko. Hlanganisa iglasi ngenye i-4 ukuya kwi-8 ye-ounces (i-120 ukuya kwi-240 mL) yamanzi kwaye usele amanzi okusela kwangoko ukuze uqiniseke ukuba uyawaginya onke amayeza.


Ugqirha wakho unokulibazisa okanye ayeke isigxina unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngegefitinib.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-gefitinib,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-gefitinib, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-gefitinib. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); izinto zokubulala ezinje nge-itraconazole (Onmel, Sporanox) kunye ne-ketoconazole (Nizoral); iMetoprolol (iLopressor, iTrolrol XL, kwiDutoprol); phenytoin (iDilantin, iPhenytek); kunye ne-tricyclic antidepressants efana ne-imipramine (Tofranil) kunye ne-amitriptyline. Uninzi lwamanye amayeza anokusebenzisana negefitinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • ukuba uthatha i-antacid okanye i-H2 iyeza lokuthintela ukungaginyeki, ukutsha kwentliziyo, okanye izilonda ezinje nge-cimetidine (Tagamet), i-famotidine (Pepcid), i-nizatidine (i-Axid), okanye i-ranitidine (i-Zantac), zibathathe ubuncinci iiyure ezi-6 ngaphambi okanye kwiiyure ezi-6 emva kokuthatha i-gefitinib.
  • ukuba uthatha iproton pump inhibitor iyeza lokugaya ukutya, isitshisa, okanye izilonda ezinje nge-esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), okanye rabeprazole (AcipHex), yithathe ubuncinci iiyure ezili-12 ngaphambi okanye ubuncinci iiyure ezili-12 emva kokuthatha i-gefitinib.
  • xelela ugqirha wakho ukuba unayo okanye wakha wanayo i-pulmonary fibrosis (scarring of the lungs) okanye enye imiphunga okanye iingxaki zokuphefumla, iingxaki zamehlo okanye umbono, okanye isifo sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. I-Gefitinib inokubangela ukungachumi (ubunzima bokukhulelwa) kwabasetyhini. Nangona kunjalo, kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho ngegefitinib kwaye ubuncinci iiveki ezi-2 emva kokuyeka ukuthatha iyeza. Ukuba ukhulelwa ngelixa uthatha i-gefitinib, tsalela ugqirha wakho. IGefitinib inokulimaza umbungu kwaye inyuse umngcipheko wokulahleka kokukhulelwa.
  • xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa uthatha i-gefitinib.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi kwedosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IGefitinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isikhumba esomileyo
  • ukurhawuzelela
  • irhashalala
  • induna
  • izilonda zomlomo
  • ubuthathaka

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

  • okutsha okanye okuba mandundu kokuphefumla, ukukhohlela, okanye umkhuhlane
  • urhudo oluqatha okanye oluqhubekayo
  • iintlungu ezinzima zesisu
  • Ukuphelelwa ngumdla wokutya
  • iintlungu zamehlo, ubomvu, okanye ukucaphuka
  • utshintsho lombono
  • Amehlo amanzi
  • ubuntununtunu bamehlo ekukhanyeni
  • urhwebo
  • i-blisters okanye i-peeling skin
  • ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, izandla, iingalo, iinyawo, amaqatha okanye imilenze esezantsi
  • isicaphucaphu
  • ukugabha
  • mthubi ulusu okanye amehlo
  • umchamo omnyama
  • izitulo ezimhlophe
  • iintlungu okanye ukungaphatheki kakuhle kwindawo ephezulu yesisu

IGefitinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-gefitinib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • UIressa®
Ukuhlaziywa kokugqibela- 12/15/2015

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