Inaliti yePegfilgrastim

Umxholo

• Xa unesixhobo se-pegfilgrastim sokuzalisa isixhobo esizenzekelayo endaweni;
• Ngaphambi kokusebenzisa imveliso yenaliti ye-pegfilgrastim,
• Iimveliso zenaliti yePegfilgrastim inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti ye-Pegfilgrastim, i-pegfilgrastim-bmez, i-pegfilgrastim-cbqv, kunye ne-pegfilgrastim-jmdb inaliti ngamayeza e-biologic (amayeza enziwe kwizinto eziphilayo). I-Biosimilar pegfilgrastim-bmez, i-pegfilgrastim-cbqv, kunye ne-pegfilgrastim-jmdb inaliti ifana kakhulu nenaliti ye-pegfilgrastim kwaye isebenza ngendlela efanayo nenaliti ye-pegfilgrastim emzimbeni. Ke ngoko, igama elithi pegfilgrastim inaliti iimveliso ziya kusetyenziswa ukumela la mayeza kule ngxoxo.

Iimveliso zenaliti zePegfilgrastim zisetyenziselwa ukunciphisa amathuba osulelo kubantu abaneentlobo ezithile zomhlaza kwaye bafumana amayeza e-chemotherapy anokunciphisa inani le-neutrophils (uhlobo lweseli yegazi olufunekayo ukulwa usulelo). Inaliti ye-Pegfilgrastim (i-Neulasta) ikwasetyenziselwa ukwandisa amathuba okusinda kubantu abaye bavezwa yimilinganiselo eyingozi yemitha, enokubangela ukonakala kunye nokusongela ubomi kumongo wethambo. I-Pegfilgrastim ikudidi lwamayeza abizwa ngokuba ziikholoni ezikhuthazayo. Isebenza ngokunceda umzimba wenze ii-neutrophils ezingakumbi.

Iimveliso zenaliti zePegfilgrastim ziza njengesisombululo (ulwelo) kwiisirinji zeenaliti ezikhethiweyo zokufaka inaliti (phantsi kolusu), nakwisixhobo esizenzekelayo senaliti (isitofu somzimba) ukufaka ulusu. Ukuba usebenzisa i-pegfilgrastim imveliso yenaliti ukunciphisa umngcipheko wosulelo ngexesha le-chemotherapy, ihlala inikwa njengedosi enye kumjikelo ngamnye wekhemotherapy, kungekudala emva kweeyure ezingama-24 emva kokuba idosi yokugqibela ye-chemotherapy yomjikelo inikiwe kwaye ngaphezulu kwe-14. kwiintsuku ngaphambi kokuqala komjikelo olandelayo wekhemotherapy. Ukuba usebenzisa i-pegfilgrastim inaliti kuba ubonakalisiwe kwimilinganiselo eyingozi yemitha, ihlala inikwa njengeedosi ezi-2 ezizodwa, i-1 ngeveki ukwahlukana. Ugqirha wakho uza kukuxelela ngokuthe ngqo xa kufuneka usebenzise iimveliso zepenfilgrastim yenaliti.

Iimveliso zepenfilgrastim inaliti unokuyinikwa ngumongikazi okanye ngomnye umboneleli wezempilo, unokuxelelwa ukuba utofe iyeza ngokwakho ekhaya, okanye ungafumana isixhobo esizenzekelayo sokuzenzela inaliti ngumongikazi okanye ngumboneleli wezempilo oza kuthi afake iyeza ngokuzenzekelayo wena ekhaya. Ukuba uza kutofa imveliso yenaliti ye-pegfilgrastim ngokwakho ekhaya, okanye ukuba ufumana isixhobo esizenzekelayo esenzelwe inaliti, umboneleli wezempilo uya kukubonisa ukuba ungalifaka njani na iyeza, okanye indlela yokulawula isixhobo. Umboneleli wakho wezempilo uya kukunika ulwazi lomenzi wesigulana. Buza umboneleli wakho wezempilo ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa imveliso yenaliti ye-pegfilgrastim ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Sukushukumisa iisirinji ezinesisombululo se-pegfilgrastim. Ngalo lonke ixesha jonga isisombululo se-pegfilgrastim ngaphambi kokufaka inaliti. Sukuwusebenzisa ukuba umhla wokuphelelwa uphelile, okanye ukuba isisombululo se-pegfilgrastim sinamasuntswana okanye sibonakala sinamafu okanye sikhanyisile.

Ukuba isisombululo sakho se-pegfilgrastim siza kwisixhobo se-injection esizenzekelayo, esi sixhobo sihlala sifakwa kwisisu sakho okanye ngasemva kwengalo yakho ngumongikazi okanye omnye umboneleli wezempilo kusuku olungaphambi kokuba ufumane idosi ye-pegfilgrastim. Ngosuku olulandelayo (malunga neeyure ezingama-27 emva kokufakwa kwesixhobo esizenzekelayo kulusu lwakho), idosi yesisombululo se-pegfilgrastim iya kufakwa ngokuzenzekelayo kwisithuba semizuzu engama-45.

Xa unesixhobo se-pegfilgrastim sokuzalisa isixhobo esizenzekelayo endaweni;

• Kuya kufuneka ubenomkhathaleli kunye nawe okokuqala xa ufumana idosi ye-pegfilgrastim okanye nangaliphi na ixesha isixhobo se-injection esizenzekelayo sisetyenziselwa emva kwengalo yakho.
• Uya kudinga ukubeka esweni isixhobo esizenzekelayo sokuzenzela inaliti ngelixa idosi yonke ye pegfilgrastim ingene emzimbeni wakho, ke kuya kufuneka uyiphephe imisebenzi kwaye ube kwiindawo ezinokuphazamisa ukubek'esweni ngelixa ufumana ithamo le-filgrastim kunye neyure e-1 emva koko.
• akufuneki uhambe, uqhube imoto, okanye usebenzise oomatshini iyure e-1 ngaphambi kunye neeyure ezi-2 emva kokuba ufumene idosi yakho ye-pegfilgrastim ngesixhobo se-injection esizenzekelayo (malunga neeyure ezingama-26 ukuya kwezingama-29 emva kokuba sifakiwe).
• Kuya kufuneka uqiniseke ukuba uyasigcina isixhobo se-injection esizenzekelayo esithandwayo ubuncinci ubuncinci i-intshi ezi-4 kude nezixhobo zombane kunye nezixhobo kubandakanya iiselfowuni, iifowuni ezingenantambo, kunye nee-oveni zemicrowave.
• Kuya kufuneka uphephe i-x-reyi yesikhululo seenqwelomoya kwaye ucele ukubambeka ngesandla xa kufuneka uhambe emva kokuba isixhobo setofisi esizenzekelayo sisetyenzisiwe emzimbeni wakho nangaphambi kokuba ufumane idosi ye-pegfilgrastim.
• kuya kufuneka ususe kwangoko isixhobo esenzelwa inaliti esizenzekelayo ukuba ngaba awufumani komzimba xa ufumana idosi yakho ye-pegfilgrastim ngokubamba umphetho wephedi yokuncamathela kwaye uyixobule. Shayela ugqirha wakho ngokukhawuleza kwaye ufumane unyango lwezonyango.
• kuya kufuneka ubize ugqirha wakho kwangoko ukuba isixhobo esenziwe kwangaphambili senaliti siphuma kulusu lwakho, ukuba isincamathelisi siba manzi ngokuphawulekayo, ukuba ubona ukuvuza kweso sixhobo, okanye ukuba ukukhanya kwesibane kukhanya kubomvu. Kuya kufuneka ugcine isixhobo esenziwe kwangaphambili senaliti simile kangangeeyure ezi-3 ngaphambi kokuba ufumane ithamo lakho le-pegfilgrastim ukukunceda uqaphele ukuba isixhobo sakho siqala ukuvuza ngelixa usamkela idosi yakho.
• Kuya kufuneka uphephe ukuvezwa kwizifundo zokucinga ngonyango (X-ray scan, MRI, CT scan, ultrasound) okanye iindawo ezinobutyebi zeoksijini (amagumbi e-hyperbaric).
• Kuya kufuneka uphephe ukulala okanye ukufaka uxinzelelo kwisixhobo senaliti esizenzekelayo.
• Kuya kufuneka uphephe iibhafu ezishushu, izivunguvungu, iisununa kunye nelanga elithe ngqo.
• Kuya kufuneka uphephe ukusebenzisa into yokuthambisa, ioyile, iizithambisi, kunye nezinto zokucoca ulusu kufutshane nesixhobo se-injection esizenzekelayo.

Ukuba isixhobo se-injection esizenzekelayo siyabengezela sibomvu, ukuba isixhobo siyaphuma ngaphambi kokuba kuhanjiswe idosi epheleleyo, okanye ukuba isincamathelisi esiba kwifowuni siba manzi okanye siphuma, fowunela ugqirha ngoko nangoko. Awunakufumana idosi epheleleyo ye-pegfilgrastim, kwaye unokufuna idosi eyongezelelweyo.

Lahla iinaliti ezisetyenzisiweyo, iisirinji kunye nezixhobo kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa imveliso yenaliti ye-pegfilgrastim,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-pegfilgrastim, i-pegfilgrastim-bmez, i-pegfilgrastim-cbqv, i-pegfilgrastim-jmdb, i-filgrastim (i-Granix, i-Neupogen, i-Nivestym, i-Zarxio). Xelela ugqirha wakho ukuba wena okanye umntu oza kufaka inaliti yemveliso ye-pegfilgrastim ye-aleji ye-latex okanye i-acrylic adhesives.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba wakhe wanomhlaza wegazi okanye umongo wethambo, okanye i-myelodysplasia (iingxaki ngeeseli zomongo wethambo ezinokuthi zikhule zibe yileukemia).
• xelela ugqirha wakho ukuba unesifo se-sickle cell (isifo segazi esinokubangela iingxaki ezibuhlungu, inani eliphantsi leeseli ezibomvu zegazi, usulelo kunye nomonakalo kwizitho zangaphakathi). Ukuba unesifo serhengqa, unokufumana ingxaki ngexesha lonyango lwakho ngemveliso yenaliti ye-pegfilgrastim. Biza ugqirha wakho ngoko nangoko ukuba unengxaki yeseli erhengqa ngexesha lonyango lwakho.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa imveliso yenaliti ye-pegfilgrastim, tsalela ugqirha wakho.
• Kuya kufuneka uyazi ukuba iimveliso zepenfilgrastim yenaliti iyanciphisa umngcipheko wosulelo kodwa ayikuthinteli lonke usulelo olunokuthi lukhule ngexesha okanye emva kwemotherapy. Fowunela ugqirha wakho xa uvela iimpawu zosulelo ezifana nomkhuhlane; Ukugodola; irhashalala; umqala obuhkungu; urhudo; okanye ubomvu, ukudumba, okanye iintlungu ezijikeleze ukusika okanye ukuqaqamba.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uza kutofa imveliso yenaliti ye-pegfilgrastim ekhaya, thetha nogqirha wakho malunga nento ekufuneka uyenzile ukuba uyalibala ukujova iyeza kwishedyuli.

Iimveliso zenaliti yePegfilgrastim inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• iintlungu zethambo
• iintlungu ezingalweni okanye emilenzeni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• iintlungu kwinxalenye ephezulu yasekhohlo yesisu okanye kwincam yegxalaba lasekhohlo
• umkhuhlane, umphefumlo omfutshane, ingxaki yokuphefumla, ukuphefumla ngokukhawuleza
• ukudumba kobuso, umqala, okanye ukujikeleza umlomo okanye amehlo, imihlathi, irhashalala, ukurhawuzelela, ingxaki yokuginya okanye ukuphefumla.
• ukudumba kobuso bakho okanye amaqatha, umchamo onegazi okanye omnyama, ukuncipha kokuchama
• umkhuhlane, iintlungu esiswini, umqolo obuhlungu, ukuziva ungaphilanga
• ukudumba kwendawo yesisu okanye okunye ukudumba, ukuncipha kokuchama, ukuphefumla okungxaki, isiyezi, ukudinwa

Iimveliso zenaliti yePegfilgrastim inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina la mayeza ebhokisini engenile, evaliwe ngokuqinileyo, kwaye kude nokufikelela kwabantwana. Gcina iimveliso zepenfilgrastim yenaliti kwifriji kodwa ungazibandisi. Ukuba ngengozi umise amayeza, ungavumela ukuba anyibilike kwifriji. Nangona kunjalo, ukuba ufriza isirinji efanayo yamayeza isihlandlo sesibini, kuya kufuneka uyilahle loo syringe. Iimveliso zepenfilgrastim yenaliti (isirinji ekhethiweyo ye-Neulasta, i-Udenyca) inokugcinwa kubushushu begumbi ukuya kuthi ga kwiiyure ezingama-48, kwaye inaliti ye-pegfilgrastim (iFulphila) inokugcinwa kubushushu begumbi ukuya kuthi ga kwiiyure ezingama-72. Iimveliso zepenfilgrastim yenaliti kufuneka igcinwe kude elangeni.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• iintlungu zethambo
• ukudumba
• ukuqhawukelwa ngumphefumlo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwimveliso yenaliti ye-pegfilgrastim.

Ngaphambi kokuba wenze isifundo sokucinga ngemathambo, xelela ugqirha wakho kunye nengcali ukuba usebenzisa imveliso yenaliti ye-pegfilgrastim. I-Pegfilgrastim inokuchaphazela iziphumo zolu hlobo lokufunda.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya.Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UFulphila^®(i-pegfilgrastim-jmdb)
• I-Neulasta^®(pegfilgrastim)
• Udenyca^®(iphepha lefilgrastim-cbqv)
• Ziextenzo (pegfilgrastim-bmez)