Dasatinib

Umxholo

• Ngaphambi kokuba uthathe i-dasatinib,
• I-Dasatinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Dasatinib isetyenziselwa ukunyanga uhlobo oluthile lwe-myeloid leukemia engapheliyo (i-CML; uhlobo lomhlaza weeseli ezimhlophe zegazi) njengonyango lokuqala kunye nakubantu abangasenako ukuxhamla kwamanye amayeza e-leukemia kubandakanya imatinib (Gleevec) okanye kwabo Awunakho ukuthatha la mayeza ngenxa yeziphumo ebezingalindelekanga. I-Dasatinib ikwasetyenziselwa ukunyanga uhlobo oluthile lwe-CML engapheliyo ebantwaneni. I-Dasatinib ikwasetyenziselwa ukunyanga uhlobo oluthile lwe-leukemia ye-lymphoblastic acute (YONKE; uhlobo lomhlaza weeseli ezimhlophe zegazi) kubantu abangasenako ukuxhamla kwamanye amayeza e-leukemia okanye abangakwaziyo ukuthatha la mayeza ngenxa yeziphumo ebezingalindelekanga. I-Dasatinib ikwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Dasatinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini, kusasa okanye ngokuhlwa, kunye okanye ngaphandle kokutya. Thatha i-dasatinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-dasatinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Nxiba iiglavu zelatex okanye iitrile xa uphethe iipilisi ezityunyuzwe ngengozi okanye ezaphukileyo ukunqanda ukudibana namayeza.

Ugqirha wakho unokuhlengahlengisa idosi yakho okanye ayeke isigxina unyango lwakho lwe-dasatinib ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Qhubeka uthathe i-dasatinib nokuba uziva uphilile. Sukuyeka ukuthatha i-dasatinib ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-dasatinib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-dasatinib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-dasatinib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-anticoagulants ('' blood thinner '') ezifana ne-warfarin (Coumadin, Jantoven); amayeza e-anthracycline yomhlaza njenge-daunorubicin (Cerubidine), doxorubicin (Doxil), kunye ne-epirubicin (Ellence); ii-antifungals ezithile ezinje nge ketoconazole (Nizoral), itraconazole (Onmel, Sporanox), kunye nevoriconazole (Vfend) i-clarithromycin (i-Biaxin, kwi-PrevPac); dexamethasone; amayeza athile asetyenziselwa ukunyanga intsholongwane kaGawulayo (i-HIV) efana ne-atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), kunye ne-saquinavir (Invirase); amayeza athile okubetha kwentliziyo okungaqhelekanga afana ne-amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), mexiletine (Mexitil), procainamide, propafenone (Rythmol), quinidine (naseNuedextol), I-Betapace, i-Betapace AF, i-Sorine), amayeza okunciphisa i-asidi esiswini njenge-cimetidine (Tagamet), i-famotidine (i-Pepcid), i-nizatidine (i-Axid), i-ranitidine (i-Zantac), i-esomeprazole (Nexium), i-lansoprazole (i-Prevacid), i-omeprazole (Prilosec) i-pantoprazole (Protonix), kunye ne-rabeprazole (AcipHex); nefazodone; irifampin (Rimactane, Rifadin, eRifater, eRifamate); kunye ne-telithromycin (Ketek); Uninzi lwamanye amayeza anokusebenzisana ne-dasatinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha ii-antacids, ezifana ne-aluminium hydroxide / i-magnesium hydroxide (Maalox), i-calcium carbonate (Tums), okanye i-calcium carbonate kunye ne-magnesium (i-Rolaids), zithathe iiyure ezi-2 ngaphambi okanye kwiiyure ezimbini emva kokuba uthathe i-dasatinib.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe wanganyamezelani i-lactose (ukungakwazi ukwetyisa iimveliso zobisi), amanqanaba asezantsi e-potassium okanye i-magnesium egazini lakho, isifo se-QT eside (imeko yentliziyo enokubangela ukuba nesiyezi, ukutyhafa, okanye ukubetha kwentliziyo ngendlela engaqhelekanga), iingxaki kunye namajoni akho omzimba, okanye isibindi, imiphunga, okanye isifo sentliziyo.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa uthatha i-dasatinib kunye neentsuku ezingama-30 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa uthatha i-dasatinib, biza ugqirha wakho. Abasetyhini abakhulelweyo akufuneki baphathe iipilisi ze-dasatinib ezityumkileyo okanye ezaphukileyo. I-Dasatinib inokulimaza umbungu.
• Musa ukuncancisa ngelixa uthatha i-dasatinib kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-dasatinib.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-dasatinib.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa uthatha eli yeza.

Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yokulinganisa Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Dasatinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• iintlungu zemisipha
• ubuthathaka
• intlungu edibeneyo
• intlungu, ukutshisa okanye ukubetha ezandleni okanye ezinyaweni
• irhashalala
• ubomvu besikhumba
• ulusu oluxobukayo
• ukudumba, ukuba bomvu, kunye neentlungu ngaphakathi emlonyeni
• izilonda zomlomo
• urhudo
• isicaphucaphu
• ukugabha
• ukuqhina
• isisu esibuhlungu okanye ukudumba
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• umkhuhlane, umqala obuhlungu, Ukugodola, kunye / okanye ezinye iimpawu zosulelo
• ukudumba kwamehlo, izandla, iingalo, iinyawo, amaqatha okanye imilenze esezantsi
• ukukhawuleza ukutyeba
• ubunzima bokuphefumla, ngakumbi xa ulele phantsi
• ukukhohlela upinki okanye i-mucus enegazi
• ukukhohlela owomileyo
• iintlungu zesifuba eziba mandundu xa ukhohlela, uthimla, okanye uphefumla nzulu
• uxinzelelo lwesifuba
• isiyezi
• isiqaqa
• ukukhawuleza kwentliziyo, ukungahambi kakuhle, okanye ukubetha kwentliziyo
• intloko ebuhlungu
• ukudinwa
• ukudideka
• ukwandiswa kwamabele okwethutyana (ebantwaneni)
• ukugruzuka okanye ukopha okungaqhelekanga
• izitulo ezimnyama kunye nokulinda
• Igazi elibomvu ilindle
• ukugabha okunegazi
• ukugabha okubonakala ngathi yindawo yekofu
• intetho ecothayo okanye enzima
• ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze

I-Dasatinib inokubangela ukukhula okucothayo okanye iintlungu zethambo ebantwaneni. Ugqirha womntwana wakho uya kubeka iliso ekukhuleni komntwana wakho ngononophelo ngelixa ethatha i-dasatinib. Thetha nogqirha wakho malunga neengozi zokunika umntwana wakho eli yeza.

I-Dasatinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukugruzuka okanye ukopha okungaqhelekanga
• umkhuhlane, umqala obuhlungu, Ukugodola, kunye / okanye ezinye iimpawu zosulelo
• ukuqhawukelwa ngumphefumlo
• ukubetha kwentliziyo ngokukhawuleza
• intloko ebuhlungu
• ulusu oluthuthu
• ukudideka
• ukudinwa

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-dasatinib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Sprycel^®