Umbhali: William Ramirez
Umhla Wokudalwa: 18 Eyomsintsi 2021
Hlaziya Umhla: 13 Eyenkanga 2024
Anonim
Ivermectin Together Trial Results from NEJM
Ividiyo: Ivermectin Together Trial Results from NEJM

Umxholo

[Ngeposi 04/10/2020]

Abaphulaphuli: Umthengi, uQeqesho kwezeMpilo, ikhemesti, ugqirha wezilwanyana

KHUPHA: I-FDA ixhalabile ngempilo yabathengi abanokuthi bazinyange ngokwabo ngokuthatha iimveliso ze-ivermectin ezilungiselelwe izilwanyana, becinga ukuba zinokuba endaweni ye-ivermectin eyenzelwe abantu.

Imvelaphi: Iziko le-FDA lezonyango lwezilwanyana kutshanje liye labona ukwanda kokubonakala esidlangalaleni kweziyobisi ze-antiparasitic ivermectin emva kokubhengezwa kwenqaku lophando elichaze ifuthe le-ivermectin kwi-SARS-CoV-2 kwindawo yeelebhu. Iphepha le-Antiviral Research elipapashwe kwangaphambili, ivermectin evunyiweyo ye-FDA inqanda ukuphindwaphindwa kwe-SARS-CoV-2 in vitro amaxwebhu ngendlela i-SARS-CoV-2 (intsholongwane ebangela i-COVID-19) iphendule ngayo kwi-ivermectin xa ivezwe kwisitya se-petri .

Ivermectin ivunyiwe yi-FDA ukuba isetyenziswe kwizilwanyana kuthintelo lwezifo zentshulube kwiintlobo ezithile zezilwanyana, kunye nonyango lwee-parasites ezithile zangaphakathi nangaphandle kwiintlobo ezahlukeneyo zezilwanyana.


UKUQONDA:

  • Abantu akufuneki bathathe iziyobisi zezilwanyana, njengoko i-FDA ivavanye kuphela ukhuseleko kunye nokusebenza kwazo kwiintlobo ezithile zezilwanyana ezibhalwe kuzo. La machiza ezilwanyana angadala ingozi enkulu ebantwini.
  • Abantu akufuneki bathathe naluphi na uhlobo lwe-ivermectin ngaphandle kokuba imiselwe ngumnikezeli wokhathalelo lwempilo kwaye ifunyenwe ngomthombo osemthethweni.
  • Ivermectin yinxalenye ebalulekileyo yenkqubo yolawulo lwesidleleli kwiintlobo ezithile kwaye kufuneka inikwe izilwanyana kuphela ukuze zisetyenziswe ngokusemthethweni okanye njengoko kumiselwe ngugqirha wezilwanyana ngokuhambelana neemfuno zokusetyenziswa gwenxa kweziyobisi.
  • Ukuba unengxaki ekufumaneni imveliso ethile ye-ivermectin yezilwanyana (i) zakho, i-FDA icebisa ukuba ubonane nogqirha wezilwanyana.

Ngolwazi oluthe kratya ndwendwela iwebhusayithi ye-FDA apha: http://www.fda.gov/Safety/MedWatch/SafetyInformation kunye ne-http: //www.fda.gov/Drugs/DrugSafety.

Ivermectin isetyenziselwa ukunyanga i-strongyloidiasis (umsonto, usulelo ngohlobo lweentshulube ezingqukuva ezingena emzimbeni ngesikhumba, ezihamba ngokuhamba komoya kunye nokuhlala emathunjini). Ivermectin ikwasetyenziselwa ukulawula i-onchocerciasis (ubumfama bomlambo; usulelo ngohlobo lweentshulube ezingqukuva ezinokubangela irhashalala, amaqhuma phantsi kolusu, kunye neengxaki zombono kubandakanya ukulahleka kombono okanye ukungaboni). Ivermectin ikudidi lwamayeza abizwa ngokuba zii-anthelmintics. Inyanga i-strongyloidosis ngokubulala iintshulube emathunjini. Inyanga i-onchocerciasis ngokubulala iintshulube ezikhulayo. Ivermectin ayizibulali iintshulube ezindala ezibangela i-onchocerciasis kwaye ke ayizukunyanga olu hlobo losulelo.


Ivermectin iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa njengethamo elinye kwisisu esingenanto ngamanzi. Ukuba uthatha ivermectin ukunyanga i-onchocerciasis, idosi eyongezelelweyo 3, 6, okanye iinyanga ezili-12 kamva kunokuba yimfuneko ukulawula usulelo lwakho. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha ivermectin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba uthatha ivermectin ukunyanga i-strongyloidiasis, kuyakufuneka ukuba ube novavanyo lokugcina isitulo ubuncinci amaxesha amathathu kwiinyanga ezintathu zokuqala emva konyango lwakho ukubona ukuba usulelekile na usulelo lwakho. Ukuba usulelo lwakho alukhange lususwe, ugqirha wakho uya kuthi amisele iidosi ezongezelelweyo ze-ivermectin.

Ivermectin ngamanye amaxesha isetyenziselwa ukunyanga ezinye izifo zentshulube, intloko okanye isifo sentwala, kunye ukhwekhwe (imeko yolusu erhawuzayo ebangelwa kukusuleleka ngamangolwane amancinci ahlala phantsi kolusu). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.


Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe ivermectin,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa ivermectin okanye naliphi na iyeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya ukuba uthatha amayeza oxinzelelo, ukugula ngengqondo okanye ukuxhuzula; izihlunu ezonwabisayo; ukuthomalalisa; iipilisi zokulala; okanye izinto ezizolisayo. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe wanayo i-meningitis, i-trypanosomiasis yabantu base-Afrika (isifo sokulala sase-Afrika; usulelo olusasazeka ngokulunywa yimpukane ye-tsetse kumazwe athile ase-Afrika), okanye iimeko ezichaphazela amajoni akho omzimba, anjengokungabikho komzimba intsholongwane (HIV).
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngexesha lonyango lwakho nge-ivermectin, tsalela ugqirha wakho.
  • buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kweziselo ezinxilisayo ngelixa uthatha ivermectin.
  • ukuba uthatha ivermectin ye-onchocerciasis, kuya kufuneka uyazi ukuba unokuba nesiyezi, ukuba nentloko ebuthathaka, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo olele kuyo. Ukuthintela le ngxaki, phuma ebhedini kancinci, uphumze iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume. Ukuba uthatha ivermectin ye-strongyloidiasis kwaye une-loiasis (Loa loa Usulelo ngohlobo lweentshulube oludala ulusu kunye nengxaki yamehlo) okanye ukuba wakhe wahlala okanye waya kwiindawo zaseNtshona okanye kuMbindi Afrika apho i-loiasis ixhaphakile, kuya kufuneka wazi ukuba unokuba nempendulo enkulu. Shayela ugqirha wakho ngokukhawuleza ukuba unamava angacacanga, iintlungu zentloko okanye zentamo, ukuxhuzula okanye ukuhamba nzima okanye ukuma.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ivermectin ihlala ithathwa njengedosi enye. Tshela ugqirha wakho ukuba awuthathi amayeza akho.

Ivermectin kunokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isiyezi
  • Ukuphelelwa ngumdla wokutya
  • isicaphucaphu
  • ukugabha
  • isisu esibuhlungu okanye ukudumba
  • urhudo
  • ukuqhina
  • ubuthathaka
  • ukozela
  • ukushukuma okungalawulekiyo kwilungu lomzimba
  • Ukungonwabi esifubeni

Ukuba uthatha ivermectin ukunyanga i-onchocerciasis, unokufumana iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ukudumba kwamehlo, ubuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
  • iintlungu ezidibeneyo kunye nokudumba
  • iintlungu ezibuhlungu nokudumba kwentamo, ikhwapha okanye iintlungu
  • ukubetha kwentliziyo ngokukhawuleza
  • iintlungu zamehlo, ukuba bomvu, okanye ukukrazula
  • ukudumba kwamehlo okanye kweenkophe
  • imvakalelo engaqhelekanga emehlweni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

  • ifiva
  • ukudumba okanye ukuxobuka kolusu
  • irhashalala
  • urhwebo
  • ukurhawuzelela

Ivermectin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • irhashalala
  • urhwebo
  • ukuxhuzula
  • intloko ebuhlungu
  • ukurhawuzelela kwezandla okanye kweenyawo
  • ubuthathaka
  • ukulahleka koququzelelo
  • isisu esibuhlungu
  • isicaphucaphu
  • ukugabha
  • urhudo
  • isiyezi
  • ukuqhawukelwa ngumphefumlo
  • ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-ivermectin.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Umyalelo wakho mhlawumbi awuyi kuphinda ugcwaliswe.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • I-Stromectol®
Ukuhlaziywa kokugqibela-05/15/2020

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