Raltegravir

Umxholo

• Ngaphambi kokuba uthathe i-raltegravir,
• I-Raltegravir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Raltegravir isetyenziswa kunye namanye amayeza ukunyanga usulelo lwe-immunodeficiency virus (HIV) kubantu abadala nakubantwana abanobunzima obungama-4.5 lbs (2 kg). URaltegravir ukwiklasi yamayeza ebizwa ngokuba yi-HIV integrase inhibitors. Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-raltegravir ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.

I-Raltegravir iza njengecwecwe, ithebhulethi ehlafunwayo, kunye negranules yokumiswa ngomlomo ukuze kuthathwe ngomlomo. IRaltegravir (Isentress^®) iipilisi, iipilisi ezihlafunwayo, kunye nokumiswa ngomlomo zihlala zithathwa kunye okanye ngaphandle kokutya kabini ngemini. IRaltegravir (Isentress^® HD) iipilisi zihlala zithathwa kunye okanye ngaphandle kokutya kanye ngemini. Thatha i-raltegravir ngexesha elinye (ii) yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-raltegravir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Ukuba uthatha amacwecwe ahlafunwayo, unokuzihlafuna okanye uziginye zizonke.

Kubantwana abanengxaki yokuhlafuna, iipilisi ezihlafunwayo zinokutyunyuzwa zixutywe ithisipuni enye (5 ml) yolwelo olufana namanzi, ijusi, okanye ubisi lwebele kwindebe ecocekileyo. Amacwecwe aya kufunxa ulwelo aze awe phakathi kwimizuzu emi-2. Usebenzisa icephe, utyumle naziphi na iziqwenga zeepilisi Sela lo mxube ngoko nangoko. Ukuba naliphi na iyeza lisele ekomityini, yongeza enye icephe (5 ml) yolwelo, jikelezisa ulithabathe kwangoko.

Ngaphambi kokuba uthathe i-raltegravir ukunqunyanyiswa ngomlomo okokuqala, funda imiyalelo ebhaliweyo eza nayo echaza indlela yokulungiselela iyeza. Khuphela imixholo yepakethi enye yegranule kwindebe yokuxuba kwaye ungeze iitispuni ezi-2 (10 ml) zamanzi. Jikelezisa kancinci imixholo kwindebe yokuxuba imizuzwana engama-45; ungangcangcazeli. Sebenzisa isirinji yedosi enikezelwe ukulinganisa isixa samayeza amiselweyo ngugqirha wakho. Sebenzisa umxube ngaphakathi kwemizuzu engama-30 yokulungiselela kwaye ulahle nakuphi na ukumiswa okushiyekileyo.

Qhubeka nokuthatha i-raltegravir nokuba uziva uphilile. Sukuyeka ukuthatha i-raltegravir okanye amanye amayeza akho okulwa i-HIV ungakhange uthethe nogqirha wakho. Ukuba uyayeka ukuthatha i-raltegravir okanye weqe amathamo, imeko yakho inokuba mandundu kwaye intsholongwane inokuxhathisa kunyango.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-raltegravir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-raltegravir, nawaphi na amanye amayeza, okanye nasiphi na isithako esivelisa iimveliso ze-raltegravir. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: ii-antacids eziqukethe i-calcium, i-magnesium, okanye i-aluminium (Maalox, Mylanta, Tums, nabanye); carbamazepine (i-Equetro, iTegretol, iTeril); cholesterol-ukunciphisa amayeza (ii-statins) ezinje nge-atorvastatin (Lipitor, eCaduet), fluvastatin (Lescol), lovastatin (Altoprev), pravastatin (Pravachol), rosuvastatin (Crestor), kunye ne-simvastatin (iZocor, eVytorin); i-etravirine (ukungakhathali); fenofibrate (Antara, Lipofen, Tricor, nabanye); gemfibrozil (iLopid); phenobarbital; phenytoin (iDilantin, iPhenytek); rifampin (Rifadin, Rimactane, eRifamate, eRifater), tipranavir (Aptivus) kunye ne ritonavir (Norvir); kunye ne-zidovudine (Retrovir, ezinye). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba uphathwa nge-dialysis (unyango lokucoca igazi xa izintso zingasebenzi kakuhle), okanye ukuba unayo okanye wakha waba ne-hepatitis, i-cholesterol ephezulu yegazi okanye i-triglycerides (izinto ezinamafutha egazini), isifo semisipha okanye ukudumba kwezihlunu, okanye i-rhabdomyolysis (imeko yemithambo).
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwe ngelixa uthatha i-raltegravir, tsalela umnxeba ugqirha wakho. Tshela ugqirha wakho ukuba uncelisa okanye uceba ukuncelisa. Akufuneki uncancise xa wosulelwe yi-HIV okanye ukuba uthatha i-raltegravir.
• ukuba une-phenylketonuria (PKU, imeko ekuyo njengelifa apho ukutya okukhethekileyo kufuneka kulandelwe ukuthintela ukudodobala kwengqondo), kuya kufuneka wazi ukuba amacwecwe ahlafunwayo aqukethe i-aspartame eyenza i-phenylalanine.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu ngexesha lonyango lwakho nge-raltegravir.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Musa ukuthatha iipilisi ezimbini ze-raltegravir ngaxeshanye ukwenza idosi ephosiweyo.

I-Raltegravir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• irhasi
• isisu esibuhlungu
• isilungulela
• ukuphuthelwa
• amaphupha angaqhelekanga
• ukudakumba
• intloko ebuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• iintlungu zemisipha okanye ukuthamba
• ubuthathaka bemisipha
• umchamo omnyama okanye wekhola
• iintlungu esifubeni okanye uxinzelelo
• irhashalala
• ifiva
• iblisters okanye ulusu
• urhwebo
• ukurhawuzelela
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, izandla, iinyawo, amaqatha okanye iingalo
• ubunzima bokuphefumla okanye ukugwinya
• ukudinwa kakhulu
• izilonda zomlomo
• ebomvu, erhawuzayo, okanye edumbileyo amehlo
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• izitulo ezimhlophe
• isicaphucaphu
• ukugabha
• Ukuphelelwa ngumdla wokutya
• ukubetha kwentliziyo ngokukhawuleza
• ukuqhawukelwa ngumphefumlo
• umkhuhlane, umqala obuhlungu, ukukhohlela, ukugodola kunye neminye imiqondiso yosulelo
• ukunqongophala kwamandla
• ukuzuza ubunzima obungachazwanga
• ukuncipha kwenani lomchamo
• ukudumba ujikeleze iinyawo, amaqatha okanye imilenze
• ukozela

I-Raltegravir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukuyisusa i-desiccant (ipakethi encinci ebandakanyiweyo kunye neepilisi ukufunxa ukufuma) kwibhotile yakho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Gcina lonke ixesha lokubonana nogqirha wakho kunye nelabhoratri ngelixa uthatha i-raltegravir. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-raltegravir.

Musa ukuvumela nabani na ukuba athathe amayeza akho.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Isentress^®
• Isentress^® HD