Bexarotene

Umxholo

• Ngaphambi kokuba uthathe i-bexarotene,
• I-Bexarotene inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

I-Bexarotene akufuneki ithathwe zizigulana ezikhulelweyo okanye ezinokukhulelwa. Kukho umngcipheko ophezulu wokuba i-bexarotene iya kubangela ukuba umntwana azalwe enesiphene sokuzalwa (iingxaki ezikhoyo ekuzalweni).

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-bexarotene.

Kwabaguli ababhinqileyo:

Ukuba unokukhulelwa, kuya kufuneka uphephe ukukhulelwa ngexesha lonyango lwakho kunye ne-bexarotene. Kuya kufuneka usebenzise iindlela ezimbini ezamkelekileyo zolawulo lokuzalwa kwinyanga e-1 ngaphambi kokuba uqale ukuthatha i-bexarotene, ngalo lonke ixesha unyango lwakho, kunye nenyanga e-1 emva konyango lwakho. Ugqirha wakho uya kukuxelela ukuba zeziphi iindlela zolawulo lokuzalwa ezamkelekileyo. I-Bexarotene inokunciphisa ukusebenza kwezicwangcisi zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa, kunye neenaliti), ke ngoko kubaluleke ngakumbi ukusebenzisa uhlobo lwesibini lolawulo lokuzalwa kunye nolu hlobo lokuthintela ukukhawula.

Uya kuqala ukuthatha i-bexarotene ngosuku lwesibini okanye lwesithathu lwexesha lakho lokuya esikhathini. Kuya kufuneka uvavanyo lokukhulelwa olungelulo phakathi kweveki e-1 yokuqala konyango lwakho kunye nenyanga nganye ngexesha lonyango lwakho. Emva kovavanyo ngalunye lokukhulelwa olubi, uya kunikwa kuphela i-bexarotene yenyanga e-1.

Yeka ukuthatha i-bexarotene kwaye ubize ugqirha wakho ngoko nangoko ukuba ucinga ukuba ukhulelwe, uyaphoswa lixesha lokuya exesheni, okanye ulala ngesondo ngaphandle kokusebenzisa iindlela ezimbini zolawulo lokuzalwa.

Kwizigulana ezingamadoda:

Kufuneka usebenzise ikhondom ngalo lonke ixesha usabelana ngesondo nomntu obhinqileyo okhulelweyo okanye okwaziyo ukukhulelwa ngelixa uthatha i-bexarotene kunye nenyanga e-1 emva konyango lwakho. Biza ugqirha wakho ukuba iqabane lakho likhulelwe ngeli xesha.

I-Bexarotene isetyenziselwa ukunyanga i-T-cell lymphoma (CTCL, uhlobo lomhlaza wolusu) kubantu abanesifo esinganyangekiyo ngempumelelo ngamanye amayeza. I-Bexarotene ikwiklasi yamayeza abizwa ngokuba yi-retinoids. Isebenza ngokumisa ukukhula kweeseli zomhlaza.

I-Bexarotene iza njengepilisi yokuthatha ngomlomo. Ihlala ithathwa kanye ngemini ngokutya. Thatha i-bexarotene malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-bexarotene ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya zonke iifomsile; musa ukuhlafuna iifomsile okanye uzinyibilikise kulwelo okanye emlonyeni wakho. Ukuba awukwazi ukuginya zonke njengezingxobo, thetha nogqirha wakho.

I-Bexarotene inokuba yingozi ukuba ingena eluswini. Musa ukuchukumisa iicapsule okanye ipowder kwiifomsile ukuba zaphukile okanye ziyavuza. Ukuba umgubo ovela kwisampuli eyaphukileyo ufika kulusu lwakho, yihlambe loo ndawo ngesepha namanzi ngokukhawuleza kwaye ubize ugqirha wakho.

Ugqirha wakho uza kukuqala ngedosi ephakathi ye-bexarotene kwaye unokunciphisa idosi yakho ukuba uneziphumo ebezingalindelekanga okanye wandise idosi ukuba imeko yakho ayiphucuki.

Kungathatha iinyanga ezininzi okanye ngaphezulu ngaphambi kokuba uqaphele isibonelelo esipheleleyo se-bexarotene. Sukuyeka ukuthatha i-bexarotene ungakhange uthethe nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-bexarotene,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-bexarotene; okanye nayiphi na enye i-retinoid, efana ne-acitretin (Soriatane), etretine (Tegison), isotretinoin (Accutane), okanye tretinoin (Vesanoid); okanye naliphi na iyeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: amiodarone (Cordarone); izinto ezithile zokubulala ukungunda ezifana ne-ketoconazole (Nizoral) kunye ne-itraconazole (Sporanox); cimetidine (iTagamet); i-clarithromycin (i-Biaxin); i-diltiazem (iCardizem); i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin); i-fluvoxamine; gemfibrozil (Lopid), HIV protease inhibitors njenge indinavir (Crixivan), nelfinavir (Viracept), kunye ne ritonavir (Norvir, e Kaletra); insulin kunye nomlomo amayeza seswekile; nefazodone; phenobarbital; phenytoin (Dilantin); irifampin (Rifadin, Rimactane); tamoxifen (Nolvadex); i-verapamil (Calan); kunye novithamini A. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akuqwalasele ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-bexarotene, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala. Xelela ugqirha wakho ukuba ukhe wafumana ipancreatitis; amanqanaba aphezulu e-cholesterol kunye nezinye izinto ezinamafutha egazini; isifo seswekile; ngamehlo; okanye inyongo, isifo sedlala, sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba uncelisa.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-bexarotene. Utywala bunokwenza iziphumo ebezingalindelekanga ukuba zibi ngakumbi.
• cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. I-Bexarotene inokwenza ulusu lwakho lubuthathaka kwilanga.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokutya nje ukuba ukhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Bexarotene inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ubuthathaka
• ukudinwa
• ukwanda kokuziva kubanda
• ukwanda kobunzima
• ukudakumba
• intlungu edibeneyo okanye yemisipha
• zibhityile, iinwele ezaphukileyo okanye iinzipho
• ukuqhina
• irhashalala
• isikhumba esomileyo
• ubomvu, ukukala, okanye ukurhawuzelela ulusu
• ukulahleka kweenwele
• ukudumba kwamaqatha, iinyawo kunye nemilenze
• ubunzima bokulala okanye ukulala
• isicaphucaphu
• ukugabha
• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ngesiquphe okanye ngokuqhubekayo iintlungu zomqolo okanye zesisu
• isicaphucaphu esiqatha nesokuqhubeka nokugabha
• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
• utshintsho kumbono

I-Bexarotene inokunyusa amanqanaba e-cholesterol kunye namanye amafutha egazini lakho kwaye inokumisa i-thyroid gland ekusebenzeni ngokuqhelekileyo. Ugqirha wakho uya kukujonga ngononophelo ukuze ubone ukuba ngaba ufumana ezinye zeempembelelo. Ukuba ufumana enye yeziphumo ebezingalindelekanga, ugqirha wakho unokumisela elinye iyeza ukulawula isiphumo esisecaleni ngelixa uthatha i-bexarotene.

I-Bexarotene inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obungaphaya, ukukhanya, kunye nobumanzi (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-bexarotene.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-bexarotene.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Targretin^® Njengezingxobo