Inaline yeLurbinectedin

Umxholo

• Ngaphambi kokufumana inaliti ye-lurbinectedin,
• I-Lurbinectedin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Inaliti yeLurbinectedin isetyenziselwa ukunyanga umhlaza wamaphaphu omncinci (i-SCLC) ethe yanwenwela kwamanye amalungu omzimba kwaye ayizange iphucule ngexesha okanye emva konyango ngeplatin chemotherapy. Inaliti yeLurbinectedin ikwiklasi yamayeza abizwa ngokuba ziiarhente zealkylating. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

Inaliti yeLurbinectedin iza njengomgubo oxutywe nolwelo ukuze ifakwe ngaphakathi ngaphakathi (emthanjeni) ngaphezulu kwemizuzu engama-60 ngugqirha okanye umongikazi esibhedlele okanye kwiziko lonyango. Ihlala inikwa kube kanye kwiintsuku ezingama-21. Ugqirha wakho uya kuthatha isigqibo sokuba uyifumana kangaphi i-lurbinectedin ngokusekwe ekuphenduleni komzimba wakho kweli yeza.

Ugqirha wakho unokufuna ukumisa okwexeshana okanye ngokusisigxina unyango lwakho okanye unciphise idosi yakho ukuba uneziphumo ebezingalindelekanga ezithile. Kubalulekile ukuba uxelele ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-lurbinectedin.

Ugqirha wakho uya kukunika iyeza lokukhusela isicaphucaphu kunye nokugabha ngaphambi kokuba ufumane idosi nganye ye-lurbinectedin.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-lurbinectedin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-lurbinectedin, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ye-lurbinectedin. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, okanye izongezo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza okubola njenge-fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), kunye ne-voriconazole (Vfend); i-clarithromycin (i-Biaxin, i-Prevpac); diltiazem (Cardizem, Dilacor, Tiazac, nabanye); erythromycin (E-mycin, Ery-Tab, nabanye); amayeza athile e-HIV afana ne-efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e Kaletra), kunye ne-saquinavir (Invirase); nefazodone; ipioglitazone (Actos, eOseni); irifabutin (Mycobutin); uqikelelo; irifampin (Rifadin, Rimactane, eRifamate, eRifater); amayeza athile okubanjwa njenge-carbamazepine (Carbatrol, Epitol, Tegretol, abanye), phenobarbital, kunye phenytoin (Dilantin, Phenytek); kunye ne-verapamil (Calan, Verelan). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-lurbinectedin, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana inaliti ye-lurbinectedin. Ugqirha wakho angenza uvavanyo lokukhulelwa ukuze aqiniseke ukuba awukhulelwe ngaphambi kokuba ufumane inaliti ye-lurbinectedin. Ukuba ungowasetyhini, kuya kufuneka usebenzise ulawulo lokuzalwa ngexesha lonyango lwakho kunye neenyanga ezi-6 emva kwedosi yakho yokugqibela. Ukuba uyindoda, wena kunye neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye nakwiinyanga ezi-4 emva kwedosi yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana inaliti ye-lurbinectedin, tsalela ugqirha wakho. Inaliti yeLurbinectedin inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa ufumana inaliti ye-lurbinectedin kwaye ubuncinci iiveki ezi-2 emva kwedosi yakho yokugqibela.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa ufumana la mayeza.

Shayela ugqirha wakho ngokukhawuleza ukuba awukwazi ukugcina ixesha lokufumana i-lurbinectedin.

I-Lurbinectedin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• Ukuphelelwa ngumdla wokutya
• iintlungu zemisipha
• intloko ebuhlungu
• ukurhawuzelela, ukuba ndindisholo, kunye nentlungu ezandleni nasezinyaweni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• ukuhamba ngombala okhanyayo, ubumthubi besikhumba okanye amehlo, ukungabinamdla wokutya, ukopha okungaqhelekanga okanye ukugruzuka, umchamo omnyama otyheli okanye omdaka, okanye iintlungu kwinxalenye ephezulu yesisu
• umkhuhlane, ukukhohlela, ukugodola, okanye ezinye iimpawu zosulelo
• ukudinwa okanye ulusu olukhanyayo

I-Lurbinectedin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-lurbinectedin.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga ne-lurbinectedin.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Zepzelca^®