Inabotulinumtoxin Inaliti

Umxholo

• Inabotulinumtoxin Inaliti (iBotox) isetyenziselwa
• Inabotulinumtoxin Inaliti (iBotox Cosmetic) isetyenziselwa
• Phambi kokuba ufumane inaliti ye-onabotulinumtoxinA,
• Inalotulinumtoxin Inaliti inokubangela iziphumo ebezingalindelekanga. Buza ugqirha wakho ukuba zeziphi na iziphumo ebezingalindelekanga onokuzibona, kuba ezinye iziphumo ebezingalindelekanga zinokwenzeka rhoqo kwinxalenye yomzimba apho wawufumene khona inaliti. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, nangaliphi na ixesha kwiiveki zokuqala emva konyango lwakho, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda, aqhele ukubonakala kanye emva kokufumana inaliti. Ukuba ufumene i-onabotulinumtoxinA okanye ukuba uthe waginya iyeza, xelela ugqirha ngoko nangoko kwaye uxelele ugqirha wakho ukuba unazo naziphi na kwezi mpawu kwezi veki zilandelayo:

Inalotulinumtoxin Inaliti inikwa njengenani lezitofu ezincinci ekujongwe ukuba zichaphazele kuphela indawo ethe yafakwa kuyo.Nangona kunjalo, kunokwenzeka ukuba iyeza lisasazeka kwindawo yenaliti kwaye lichaphazele izihlunu kwezinye iindawo zomzimba. Ukuba izihlunu ezilawula ukuphefumla nokuginya zichaphazelekile, unokuba neengxaki ezinzima zokuphefumla okanye ukugwinya okunokuhlala iinyanga ezininzi kwaye kunokubangela ukufa. Ukuba unobunzima bokuginya, unokufuna ukondliwa ngombhobho wokutya ukunqanda ukufumana ukutya okanye isiselo kwimiphunga yakho.

Inabotulinumtoxin Inaliti inokusasazeka kwaye ibangele iimpawu kubantu bayo nayiphi na iminyaka abanyangwa ngayo nayiphi na imeko, nangona kungekho namnye umntu osele ezivelisile ezi mpawu emva kokufumana amayeza ngeedosi ezinconyelweyo ukunyanga imibimbi, iingxaki zamehlo, intloko ebuhlungu, okanye ukubila okungaphantsi kwekhwapha. Umngcipheko wokuba iyeza liza kusasazeka ngaphaya kwendawo yenaliti mhlawumbi liphezulu kubantwana abanyangelwa ukuqina (ukuqina kwemisipha kunye nokuqina) nakubantu, abanengxaki yokuginya, okanye yokuphefumla, njenge-asthma okanye emphysema; okanye nayiphi na imeko echaphazela izihlunu okanye imithambo-luvo efana ne-amyotrophic lateral sclerosis (ALS, isifo sikaLou Gehrig; imeko apho imithambo-luvo elawula ukushukuma kwemisipha isifa kancinci, ibangela ukuba izihlunu zinciphe kwaye zenze buthathaka), motor neuropathy (imeko apho izihlunu zibuthathaka khona Ngokuhamba kwexesha), myasthenia gravis (imeko ebangela ukuba izihlunu ezithile zibuthathaka, ngakumbi emva komsebenzi), okanye iLambert-Eaton syndrome (imeko ebangela ubuthathaka bemisipha enokuthi iphucule ngomsebenzi). Tshela ugqirha wakho ukuba ukhe wakha wanayo na le meko.

Ukusasazeka kwe-onabotulinumtoxin Inaliti kwiindawo ezinganyangekiyo inokubangela ezinye iimpawu ukongeza kubunzima bokuphefumla okanye ukugwinya. Iimpawu zinokwenzeka kwiiyure zenaliti okanye emva kweeveki ezimbalwa emva konyango. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko ugqirha okanye ufumane unyango olukhawulezileyo: ukuphelelwa ngamandla okanye izihlunu ezibuthathaka emzimbeni wonke; ukubona kabini okanye ukungaboni kakuhle; ukujingisa iinkophe okanye ibunzi; ubunzima bokuginya okanye ukuphefumla; Ukudakumba okanye ukutshintsha okanye ukulahleka kwelizwi; kunzima ukuthetha okanye ukuthetha amagama ngokucacileyo; okanye ukungakwazi ukulawula ukuchama.

Ugqirha wakho uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-onabotulinumtoxinA kwaye ngalo lonke ixesha ufumana unyango. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Inaliti ye-Onabotulinumtoxin Inaliti (iBotox, iBotox Cosmetic) isetyenziselwa ukunyanga iimeko ezininzi.

Inabotulinumtoxin Inaliti (iBotox) isetyenziselwa

• phelisa iimpawu zedystonia yomlomo wesibeleko (spasmodic torticollis; ukuqina okungalawulekiyo kwezihlunu zentamo ezinokubangela iintlungu zentamo kunye nezikhundla zentloko ezingaqhelekanga) kubantu abaneminyaka eli-16 nangaphezulu;
• phelisa iimpawu ze-strabismus (ingxaki yemisipha yamehlo ebangela ukuba iliso liphendukele ngaphakathi okanye ngaphandle) kunye ne-blepharospasm (ukuqiniswa okungalawulekiyo kwemisipha yeenkophe ezinokubangela ukuqhwanyaza, ukuqhwanyaza, kunye nokuhamba okungaqhelekanga kwejwabu leso) kubantu abaneminyaka eli-12 ubudala nangaphezulu;
• thintela iintloko kubantu abadala kuneminyaka eyi-18 ubudala abane-migraine engapheliyo (enzima, ebuhlungu entloko maxa wambi ehamba nesicaphucaphu kunye nobuntununtunu kwisandi okanye ukukhanya) abaneentsuku ezili-15 okanye nangaphezulu inyanga nganye abaneentloko ezihlala iiyure ezi-4 ngosuku okanye nangaphezulu;
• ukunyanga isinyi esisebenzayo (imeko apho izihlunu zesinyi zisebenza ngokungalawulekiyo kwaye zibangela ukuchama rhoqo, isidingo esingxamisekileyo sokuchama, kunye nokungakwazi ukulawula ukuchama) kubantu abaneminyaka eli-18 ubudala nangaphezulu xa amanye amayeza engasebenzi kakuhle okanye engenakuthathwa;
• ukunyanga ukungalawuleki (ukuvuza komchamo) kubantu abaneminyaka eli-18 ubudala nangaphezulu ngesinyi esingaphezulu (imeko apho izihlunu zesinyi zineziphatho ezingalawulekiyo) ezibangelwa ziingxaki zemithambo-luvo ezinje ngokulimala kwentambo yomqolo okanye isifo sokuqina kwemithambo (MS; isifo apho imithambo-luvo ayisebenzi ngokufanelekileyo kwaye abantu banokufumana ubuthathaka, ukuba ndindisholo, ukuphulukana nokulungelelaniswa kwezihlunu, kunye neengxaki zombono, intetho, kunye nolawulo lwesinyi), abangenakuphathwa ngamayeza omlomo;
• phatha ukuqina (ukuqina kwemisipha kunye nokuqina) kwezihlunu ezingalweni nasemilenzeni kubantu abaneminyaka emi-2 ubudala nangaphezulu;
• phatha ukubila okungaphantsi kwekhwapha kubantu abaneminyaka eli-18 ubudala nangaphezulu abangenakuphathwa ngeemveliso ezifakwe kulusu;

kwaye

Inabotulinumtoxin Inaliti (iBotox Cosmetic) isetyenziselwa

• Imigca efinyeneyo okwethutyana (imibimbi phakathi kwamashiya) kubantu abadala abaneminyaka eli-18 nangaphezulu,
• Imigca yeenyawo ezinqabileyo okwethutyana (imibimbi kufutshane nekona yangaphandle yeliso) kubantu abadala abaneminyaka eli-18 ubudala nangaphezulu,
• kunye nokutyibilika okwethutyana emigceni ebunzi kubantu abadala abaneminyaka eyi-18 nangaphezulu.

Inalotulinumtoxin Inaliti ikwiklasi yamayeza abizwa ngokuba zii-neurotoxins. Xa i-onabotulinumtoxinA ingene kwimisipha, ibhloka imiqondiso ye-nerve ebangela ukuqiniswa okungalawulekiyo kunye nokuhamba kwemisipha. Xa i-onabotulinumtoxinA ifakwe kwi-sweat gland, iyanciphisa umsebenzi we-gland ukunciphisa ukubila. Xa i-onabotulinumtoxinA ifakwe kwi-bladder, iyanciphisa ukucinywa kwesinyi kunye neebhloko ezithintela inkqubo ye-neva ukuba isinyi sigcwele.

Inabotulinumtoxin Inaliti iza njengomgubo oxutywe nolwelo kwaye ufakwe ngaphakathi kwimisipha, eluswini, okanye eludongeni lwesinyi ngugqirha. Ugqirha wakho uya kukhetha eyona ndawo ifanelekileyo yokufaka iyeza kunyango lwakho. Ukuba ufumana i-onabotulinumtoxinA ukunyanga imigca ebusileyo, imigca yebunzi, imigca yeenyawo zecrow, i-dystonia yomlomo wesibeleko, i-blepharospasm, i-strabismus, ukunganyamezeleki, ukungabikho komchamo, isinyi kakhulu, okanye i-migraine engapheliyo, unokufumana inaliti eyongezelelweyo rhoqo kwiinyanga ezi-3 ukuya kwezi-4, kuxhomekeke imeko kunye nokuba zide kangakanani iziphumo zonyango. Ukuba ufumana i-onabotulinumtoxinA inaliti ukunyanga ukubila okungaphantsi kwekhwapha, unokufuna ukufumana inaliti eyongezelelweyo kanye kwiinyanga ezi-6 ukuya kwezi-7 okanye xa iimpawu zakho zibuya.

Ukuba ufumana i-onabotulinumtoxinA inaliti ukunyanga ukubila okungaphantsi kwekhwapha, ugqirha wakho uya kuthi enze uvavanyo ukuze afumane iindawo ekufuneka zinyangwe. Ugqirha wakho uza kukuxelela indlela yokulungiselela olu vavanyo. Uya kuthi uxelelwe ukuba uchebe izikhwapha zakho kwaye ungasebenzisi iziyobisi ezingabhaliswanga okanye ii-antiperspirants iiyure ezingama-24 ngaphambi kovavanyo.

Ukuba ufumana i-onabotulinumtoxinA inaliti yokunyanga ukungasebenzi komchamo, ugqirha wakho unokukunika amayeza okubulala iintsholongwane ukuze uthathe iintsuku eziyi-1-3 ngaphambi konyango lwakho, ngosuku lonyango lwakho kunye neentsuku ezi-1 ukuya kwezi-3 emva konyango lwakho.

Ugqirha wakho unokutshintsha idosi yakho ye-onabotulinumtoxinA inaliti ukuze ufumane idosi eya kukusebenzela ngcono.

Ugqirha wakho unokusebenzisa i-cream ye-anesthetic, okanye ipakethe ebandayo, ukuphazamisa isikhumba sakho, okanye ukuhla kwamehlo ukukhupha amehlo akho ngaphambi kokujova i-onabotulinumtoxinA.

Olunye uphawu okanye uhlobo lwe-botulinum toxin alunakufakwa endaweni yenye.

Inalotulinumtoxin Inaliti inokunceda ukulawula imeko yakho kodwa ayizukuyinyanga. Kungathatha iintsuku ezimbalwa okanye ukuya kwiiveki ezimbalwa ngaphambi kokuba uve isibonelelo esipheleleyo senaliti ye-onabotulinumtoxinA. Buza ugqirha wakho xa unokulindela ukubona ukuphucuka, kwaye ubize ugqirha wakho ukuba iimpawu zakho aziphucuki ngexesha elilindelekileyo.

InabotulinumtoxinA inaliti ngamanye amaxesha isetyenziselwa ukunyanga ezinye iimeko apho ukuqina kwesihlunu okungaqhelekanga kubangela iintlungu, iintshukumo ezingaqhelekanga, okanye ezinye iimpawu. Inabotulinumtoxin Inaliti ngamanye amaxesha isetyenziselwa ukunyanga ukubila okugqithisileyo kwezandla, iintlobo ezininzi zemibimbi yobuso, ukungcangcazela (ukungcangcazela okungalawulekiyo kwenxalenye yomzimba), kunye nokuqhekeka kwe-anal (ukwahlukana okanye ukukrazula izicubu ezikufutshane nendawo engxenyeni) . Amayeza ngamanye amaxesha asetyenziselwa ukuphucula ukubanakho ukuhamba kubantwana abanesifo sokukhubazeka kwengqondo (imeko ebangela ubunzima ngokuhamba kunye nokulingana). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokuba ufumane inaliti ye-onabotulinumtoxinA,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba u-aleabotulinumtoxinA, abobotulinumtoxinA (Dysport), incobotulinumtoxinA (Xeomin), prabotulinumtoxinA-xvfs (Jeuveau), okanye rimabotulinumtoxinB (Myobloc). Kwakhona xelela ugqirha wakho ukuba ngaba uxabana nalo naliphi na iyeza okanye nasiphi na isithako kwiinaliti ye-onabotulinumtoxinA. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza athile afana ne-amikacin, clindamycin (Cleocin), colistimethate (Coly-Mycin), gentamicin, kanamycin, lincomycin (Lincocin), neomycin, polymyxin, streptomycin, kunye ne-tobramycin; ii-anticoagulants (’izinciphisi zegazi’) ezifana ne-warfarin (Coumadin, Jantoven); antihistamines; i-aspirin kunye nezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); c heparin; amayeza e-aleji, ukubanda, okanye ukulala; izihlunu ezonwabisayo; kunye nee-platelet inhibitors ezinjenge-clopidogrel (Plavix). dipyridamole (Persantine, kwiAgrenrenox), prasugrel (Effient), kunye ticlopidine (Ticlid). Xelela ugqirha wakho ukuba ufumene inaliti yayo nayiphi na imveliso yetyhefu ye-botulinum kubandakanya i-abobotulinumtoxinA (Dysport), incobotulinumtoxinA (Xeomin), prabotulinumtoxinA-xvfs (Jeuveau), okanye rimabotulinumtoxinB (Myobloc) kwezi nyanga zine zidlulileyo. Ugqirha wakho unokufuna ukutshintsha idosi okanye ishedyuli yamayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-onabotulinumtoxinA, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba unokudumba okanye ezinye iimpawu zosulelo okanye ubuthathaka kwindawo apho i-onabotulinumtoxinA iya kutofelwa khona. Ugqirha wakho ngekhe afake iyeza kwindawo enesifo okanye ebuthathaka.
• ukuba uza kufumana i-onabotulinumtoxinA inaliti yokunyanga ukungangqinelani komchamo, xelela ugqirha wakho ukuba unosulelo lwe-urinary tract (UTI), olunokubandakanya iimpawu ezinjengentlungu okanye ukutshisa xa uchama, ukuchama rhoqo, okanye umkhuhlane; okanye ukuba ugcina umchamo (ukungakwazi ukukhupha isinyi ngokupheleleyo) kwaye musa ukusikhupha rhoqo ngesinye isitshizi. Ugqirha wakho ngekhe angakuphathi ngenaliti ye-onabotulinumtoxinA.
• xelela ugqirha wakho ukuba wakhe wanayo nayiphi na imiphumo emibi evela kuyo nayiphi na imveliso ye-botulinum toxin, okanye utyando lwamehlo okanye lobuso, ukuba ukhe wanengxaki yokopha; ukuxhuzula; i-hyperthyroidism (imeko eyenzeka xa idlala lengqula livelisa kakhulu idlala lengqula), isifo seswekile, okanye imiphunga okanye isifo sentliziyo.
• ukuba uza kufumana i-onabotulinumtoxinA inaliti yokunyanga imibimbi, ugqirha wakho uya kukuvavanya ukuze abone ukuba ngaba amayeza anokusebenzela wena. Inabotulinumtoxin Inaliti inokungagudisi imibimbi yakho okanye inokubangela ezinye iingxaki ukuba uneenkophe ezijingayo; ingxaki yokunyusa amashiya akho; okanye naluphi na olunye utshintsho kwindlela obujongeka ngayo ubuso bakho.
• ukuba uneminyaka engama-65 nangaphezulu kwaye uza kufumana i-onabotulinumtoxinA (Botox Cosmetic) inaliti yokugungxula iinyawo zegwababa okwexeshana, imigca yebunzi, okanye imigca efinyeneyo, kuya kufuneka uyazi ukuba olu nyango alusebenzanga nakubantu abadala abadala xa kuthelekiswa nabantu abadala abangaphantsi kweminyaka engama-65 iminyaka yobudala.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana inabotulinumtoxinA inaliti, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inabotulinumtoxinA inaliti.
• Kuya kufuneka uyazi ukuba inabotulinumtoxinInaliti inokubangela ukulahleka kwamandla okanye ubuthathaka bemisipha kuwo wonke umzimba okanye umbono ongalunganga. Ukuba unayo nayiphi na kwezi mpawu, musa ukuqhuba imoto, sebenzisa oomatshini, okanye wenze ezinye izinto eziyingozi.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inalotulinumtoxin Inaliti inokubangela iziphumo ebezingalindelekanga. Buza ugqirha wakho ukuba zeziphi na iziphumo ebezingalindelekanga onokuzibona, kuba ezinye iziphumo ebezingalindelekanga zinokwenzeka rhoqo kwinxalenye yomzimba apho wawufumene khona inaliti. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• iintlungu, ukuthamba, ukudumba, ukuba bomvu, ukopha, okanye ukugruzuka kwindawo obufumene kuyo inaliti
• ukudinwa
• intlungu yentamo
• intloko ebuhlungu
• ukozela
• iintlungu zemisipha, ukuqina, ukuqina, ubuthathaka, okanye ispasm
• intlungu okanye ukuqina ebusweni okanye entanyeni
• umlomo owomileyo
• isicaphucaphu
• ukuqhina
• ixhala
• ukubila kumalungu omzimba ngaphandle kwezandla zangaphantsi
• ukukhwehlela, ukuthimla, umkhuhlane, ukuxinana kwempumlo, okanye umqala obuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, nangaliphi na ixesha kwiiveki zokuqala emva konyango lwakho, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• Ukuphinda kabini, ukungaboni kakuhle, okanye ukunciphisa umbono
• ukudumba kweenkophe
• utshintsho lombono (njengobuntununtunu bokukhanya okanye ukungaboni kakuhle)
• owomileyo, ocaphukisayo, okanye amehlo abuhlungu
• ubunzima bokuhambisa ubuso
• ukuxhuzula
• ukubetha kwentliziyo ngokungaqhelekanga
• iintlungu zesifuba
• iintlungu ezingalweni, emqolo, entanyeni, okanye emhlathini
• ukuqhawukelwa ngumphefumlo
• isiqaqa
• isiyezi
• irhashalala
• urhwebo
• ukurhawuzelela
• ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukukhohlela, ukukhohlela amafinyila, umkhuhlane, okanye ukubanda
• ukungakwazi ukukhupha isinyi sakho ngokwakho
• intlungu okanye ukutshisa xa uchama okanye uchama rhoqo
• igazi kumchamo
• ifiva

InalotulinumtoxinInaliti inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda, aqhele ukubonakala kanye emva kokufumana inaliti. Ukuba ufumene i-onabotulinumtoxinA okanye ukuba uthe waginya iyeza, xelela ugqirha ngoko nangoko kwaye uxelele ugqirha wakho ukuba unazo naziphi na kwezi mpawu kwezi veki zilandelayo:

• ubuthathaka
• ubunzima bokuhambisa naliphi na ilungu lomzimba wakho
• ubunzima bokuphefumla
• kunzima ukugwinya

Gcina lonke ixesha lokudibana nogqirha wakho.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-onabotulinumtoxinA.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IBotox^®
• IBotox^® Izithambiso

• I-BoNT-A
• I-BTA
• Uhlobo lweBotulinum Toxin