IPolymyalgia rheumatica

I-Polymyalgia rheumatica (PMR) sisifo esidumbisayo. Kubandakanya iintlungu kunye nokuqina kwamagxa kwaye zihlala zisisinqe.

I-Polymyalgia rheumatica ihlala isenzeka kubantu abangaphezu kweminyaka engama-50 ubudala. Unobangela awaziwa.

I-PMR inokwenzeka ngaphambi okanye nge-giant cell arteritis (GCA; ekwabizwa ngokuba yi-tempter arteritis). Le yimeko apho imithambo yegazi ebonelela ngegazi entloko nakwiliso idumbile.

I-PMR ngamanye amaxesha kunokuba nzima ukuyichaza ngaphandle kwe-rheumatoid arthritis (RA) kumntu omdala. Oku kwenzeka xa kuvavanywa into ye-rheumatoid factor kunye ne-anti-CCP antibody.

Olona phawu luxhaphakileyo yintlungu kunye nokuqina kwamagxa amabini kunye nentamo. Intlungu kunye nokuqina kubi kakhulu kusasa. Le ntlungu ihlala iqhubela esinqeni.

Ukudinwa kukwakho. Abantu abakule meko bakufumanisa kunzima ngakumbi ukuphuma ebhedini nokuhambahamba.

Ezinye iimpawu zibandakanya:

• Ukulahleka kokutya, okukhokelela ekunciphiseni umzimba
• Uxinzelelo
• Ifiva

Uvavanyo lwelebhu lulodwa alunakufumanisa i-PMR. Uninzi lwabantu abanale meko banamanqaku aphezulu okuvuvukala, anje nge-sedimentation rate (ESR) kunye ne-C-esebenzayo yeprotein.

Ezinye iziphumo zovavanyo zale meko zibandakanya:

• Amanqanaba angaqhelekanga eeproteni egazini
• Inqanaba elingaqhelekanga leeseli ezimhlophe zegazi
• I-anemia (ukubala okuphantsi kwegazi)

Ezi mvavanyo zingasetyenziselwa ukubeka esweni imeko yakho.

Nangona kunjalo, iimvavanyo zokucinga ngemifanekiso ezinje ngee-x-ray zamagxa okanye ezinqeni azihlali ziluncedo. Ezi mvavanyo zinokuveza umonakalo odibeneyo ongahambelani neempawu zamva nje. Kwiimeko ezinzima, i-ultrasound okanye i-MRI yegxala ingenziwa. Ezi mvavanyo zokucinga zihlala zibonisa i-bursitis okanye amanqanaba asezantsi okudumba ngokudibeneyo.

Ngaphandle konyango, i-PMR ayibi bhetele. Nangona kunjalo, iidosi ezisezantsi ze-corticosteroids (ezinje nge-prednisone, 10 ukuya kwi-20 mg ngosuku) zinokunciphisa iimpawu, zihlala ngaphakathi kosuku okanye ezimbini.

• Umthamo kufuneka emva koko uncitshiswe kancinci ukuya kwinqanaba eliphantsi kakhulu.
• Unyango kufuneka luqhubeke iminyaka eyi-1 ukuya kwe-2. Kwabanye abantu, unyango olude kunye nedosi ephantsi ye-prednisone iyafuneka.

I-Corticosteroids inokubangela iziphumo ebezingalindelekanga ezininzi njengokufumana ubunzima, ukukhula kwesifo seswekile okanye i-osteoporosis. Kufuneka ujongwe ngononophelo ukuba uthatha la mayeza. Ukuba usemngciphekweni we-osteoporosis, umboneleli wakho wezempilo angakucebisa ukuba uthathe amayeza ukuthintela le meko.

Kubantu abaninzi, i-PMR ihamba nonyango emva kweminyaka eyi-1 ukuya kwezi-2. Unokwazi ukuyeka ukuthatha amayeza emva kweli nqaku, kodwa jonga kumboneleli wakho kuqala.

Abanye abantu, iimpawu ziyabuya emva kokuyeka ukuthatha i-corticosteroids. Kule meko, elinye iyeza elinjenge-methotrexate okanye i-tocilizumab linokufuneka.

Iseli enkulu ye-arteritis inokubakho okanye inokukhula kamva. Ukuba kunjalo, i-artery yexeshana iya kufuna ukuvavanywa.

Iimpawu ezinzima kakhulu zinokukwenza kube nzima kuwe ukuba usebenze okanye uzikhathalele ekhaya.

Biza umnikezeli wakho ukuba unobuthathaka okanye ukuqina egxalabeni nasentanyeni engahambiyo. Nxibelelana nomboneleli wakho ukuba uneempawu ezintsha ezinje ngomkhuhlane, intloko ebuhlungu, kunye nentlungu ngokuhlafuna okanye ukulahleka kombono. Ezi mpawu zinokuba zivela kwi-arteritis enkulu yeseli.

Akukho sithintelo saziwayo.

PMR

UDejaco C, uSingh YP, uPerel P, et al. Izindululo zika-2015 kulawulo lwe-polymyalgia rheumatica: I-European League ngokuchasene neRheumatism / Ikholeji yaseMelika yeRheumatology yokusebenzisana. Isifo samathambo Rheumatol. Ngo-2015; 67 (10): 2569-2580. IINKCUKACHA: 2635874 www.ncbi.nlm.nih.gov/pubmed/26352874.

IHellmann DB. Iseli enkulu ye-arteritis, i-polymyalgia rheumatica, kunye ne-Takayasu's arteritis. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, ii-eds. Incwadi kaKelley kunye neFirestein yeRheumatology. Ngomhla we-10. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 88.

IKermani TA, iWarrington KJ. Ukuqhubela phambili kunye nemiceli mngeni kuxilongo kunye nonyango lwe-polymyalgia rheumatica. Unyango lwe-Ther Adv Musculoskelet Dis. Ngo-2014; 6 (1): 8-19. IINKCUKACHA: 24489611 www.ncbi.nlm.nih.gov/pubmed/24489611.

USalvarani C, uCiccia F, uPipitone N. Polymyalgia rheumatica kunye neseli enkulu ye-arteritis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, ii-eds. Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2019: isahluko 166.