Inaliti yeBendamustine

Umxholo

• Ngaphambi kokufumana inaliti ye-bendamustine,
• Inaliti ye-Bendamustine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti ye-Bendamustine isetyenziselwa ukunyanga i-lymphocytic leukemia (CLL; uhlobo lomhlaza weeseli ezimhlophe zegazi). Inaliti ye-Bendamustine ikwasetyenziselwa ukunyanga uhlobo lwe-non-Hodgkins lymphoma (NHL: umhlaza oqala kuhlobo lweeseli ezimhlophe zegazi ezilwa nosulelo) olucothayo ukusasazeka, kodwa luqhubekile luba mandundu ngexesha okanye emva konyango ngamanye amayeza. I-Bendamustine ikwiklasi yamayeza abizwa ngokuba ziiarhente ze-alkylating. Isebenza ngokubulala iiseli zomhlaza ezikhoyo kunye nokunciphisa ukukhula kweeseli zomhlaza ezintsha.

I-Bendamustine iza njengesisombululo (ulwelo) okanye njengomgubo oxutywe nolwelo kwaye ifakwe inaliti (emthanjeni) ngaphezulu kwemizuzu eli-10 okanye ifakwe ngaphakathi ngemizuzu engama-30 okanye engama-60 ngugqirha okanye umongikazi kwiofisi yezonyango okanye kwiklinikhi yokugula kwesibhedlele. Xa kusetyenziswa inaliti ye-bendamustine ukunyanga i-CLL, ihlala itofwa kanye ngemini kangangeentsuku ezi-2, ilandelwe ziintsuku ezingama-26 xa iyeza linganikwanga. Eli xesha lonyango libizwa ngokuba ngumjikelo, kwaye umjikelo unokuphindaphindwa rhoqo kwiintsuku ezingama-28 ixesha elide njengemijikelezo emi-6. Xa kusetyenziswa inaliti ye-bendamustine ukunyanga i-NHL, ihlala itofwa kanye ngemini kangangeentsuku ezi-2, ilandelwe ziintsuku ezili-19 xa iyeza linganikwanga. Lo mjikelo wonyango unokuphindaphindwa rhoqo emva kweentsuku ezingama-21 ukuya kuthi ga kwimijikelo ye-8.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho kwaye ahlengahlengise idosi yakho ukuba uneziphumo ebezingalindelekanga ezithile. Ugqirha wakho unokukunika amanye amayeza ukukhusela okanye ukunyanga iziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-bendamustine.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-bendamustine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-bendamustine, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-bendamustine injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ciprofloxacin (Cipro), fluvoxamine (Luvox, kunye ne-omeprazole (Prilosec) .Ugqirha wakho kungafuneka atshintshe amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. , ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe wosulelwa yi-cytomegalovirus (i-CMV; usulelo lwentsholongwane olunokubangela iimpawu kwizigulana ezinamajoni omzimba abuthathaka), usulelo lwentsholongwane ye-hepatitis B (HBV; usulelo oluqhubekayo lwesibindi), isifo sephepha (TB; usulelo olubi echaphazela imiphunga kwaye ngamanye amaxesha amanye amalungu omzimba), i-herpes zoster (i-shingles; irhashalala enokuthi ibekho kubantu abanenkukhu ngaphambili), okanye isifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana inaliti ye-bendamustine. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa kuwe okanye kwiqabane lakho ngexesha lonyango lwakho ngenaliti ye-bendamustine kunye neenyanga ezi-3 emva koko. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana inaliti ye-bendamustine, tsalela ugqirha wakho. Inaliti ye-Bendamustine inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngexesha lonyango lwakho nge-bendamustine.
• Kuya kufuneka uyazi ukuba inaliti ye-bendamustine inokukwenza udinwe. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• xelela ugqirha wakho ukuba usebenzisa iimveliso zecuba. Ukutshaya kunokunciphisa ukusebenza kweli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Shayela ugqirha wakho ngokukhawuleza ukuba awukwazi ukugcina ixesha lokufumana i-dose ye-bendamustine injection.

Inaliti ye-Bendamustine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• isilungulela
• ukuqhina
• isisu esibuhlungu okanye ukudumba
• izilonda okanye amabala amhlophe emlonyeni
• umlomo owomileyo
• incasa embi emlonyeni okanye ubunzima ukungcamla ukutya
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• intloko ebuhlungu
• ixhala
• ukudakumba
• ubunzima bokulala okanye ukulala
• umqolo, ithambo, ilungu, ingalo okanye iintlungu emlenzeni
• isikhumba esomileyo
• ukubila
• ukubila ebusuku

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• iintlungu kwindawo apho lalifakwe khona iyeza
• urhwebo
• irhashalala
• ukurhawuzelela
• ukudumba okanye ukuxobuka kolusu
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukuqhawukelwa ngumphefumlo
• iintlungu zesifuba
• ukubetha kwentliziyo ngokukhawuleza
• ukudinwa kakhulu okanye ubuthathaka
• ulusu oluthuthu
• umkhuhlane, ukugodola, ukukhohlela, okanye ezinye iimpawu zosulelo
• isicaphucaphu; ukugabha; ukopha okungaqhelekanga okanye ukugruzuka; tyheli kolusu okanye lamehlo, umchamo omnyama, okanye isitulo esikhanyayo; ukuthamba kwicala lasekunene lesisu

Inaliti ye-Bendamustine inokubangela ukungachumi kwamanye amadoda. Oku kungachumi kunokuphela emva konyango, kunokuhlala iminyaka eliqela, okanye kunokuhlala ngokusisigxina. Thetha nogqirha wakho malunga neengozi zokufumana eli yeza.

Abanye abantu bavelise ezinye iintlobo zomhlaza ngelixa besebenzisa inaliti ye-bendamustine. Akukho lwazi lwaneleyo ukuxelela ukuba ngaba inaliti ye-bendamustine ibangele ukuba le mihlaza ikhule. Thetha nogqirha wakho malunga neengozi zokufumana eli yeza.

Inaliti ye-Bendamustine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukukhawuleza kwentliziyo, ukungahambi kakuhle, okanye ukubetha kwentliziyo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwinaliti ye-bendamustine.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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