Imixholo yeBexarotene

Umxholo

• Sebenzisa ijeli, landela la manyathelo:
• Ngaphambi kokusebenzisa i-bexarotene,
• Imixholo ye-bexarotene inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

I-bexarotene yesihloko isetyenziselwa ukunyanga i-T-cell lymphoma (CTCL, uhlobo lomhlaza wolusu) olungenakuphathwa ngamanye amayeza. I-Bexarotene ikwiklasi yamayeza abizwa ngokuba yi-retinoids. Isebenza ngokumisa ukukhula kweeseli zomhlaza.

Imixholo ye-bexarotene iza njengejeli ukufaka ulusu. Ihlala isetyenziswa kube kanye yonke imihla ekuqaleni kwaye ngokuthe ngcembe isetyenziswa rhoqo ukuya kuthi ga kwizihlandlo ezibini ukuya kwezine ngosuku. Sebenzisa i-bexarotene yesihloko ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-bexarotene ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-bexarotene yezihloko kunye nokunyusa ngokuthe ngcembe idosi yakho, hayi rhoqo ngaphezulu kweveki. Ugqirha wakho unokunciphisa umthamo wakho ukuba unemiphumo emibi.

Imeko yakho inokuphuculwa kwakamsinya emva kweeveki ezi-4 emva kokuba uqale ukusebenzisa i-bexarotene, okanye kungathatha iinyanga ezininzi ngaphambi kokuba uqaphele naluphi na uphuculo. Qhubeka nokusebenzisa i-bexarotene engundaba-mlonyeni emva kokuba uqaphele ukuphucula; imeko yakho ingaqhubeka ukuphucula. Sukuyeka ukusebenzisa i-bexarotene engundaba-mlonyeni ngaphandle kokuthetha nogqirha wakho.

Ijeli yeBexarotene inokubamba umlilo. Sukusebenzisa la mayeza kufutshane nomthombo wobushushu okanye kufutshane nedangatye elivulekileyo elinjengecuba.

Ijeli yeBexarotene yenzelwe ukusetyenziswa kwangaphandle kuphela. Musa ukuginya amayeza kwaye ugcine iyeza kude namehlo akho, iimpumlo, umlomo, imilebe, ubufazi, incam yelungu lobudoda, i-rectum kunye ne-anus.

Unokuhlamba, uhlambe, okanye uqubha ngexesha lonyango lwakho kunye ne-bexarotene, kodwa kufuneka usebenzise kuphela isepha engenasiphelo. Kuya kufuneka ulinde ubuncinci imizuzu engama-20 emva kokuhlamba okanye ukuhlamba ngaphambi kokufaka i-bexarotene. Emva kokufaka iyeza, musa ukuhlamba, ukuqubha, okanye ishawa okungenani iiyure ezintathu.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Sebenzisa ijeli, landela la manyathelo:

1. Hlamba izandla zakho.
2. Ukuba usebenzisa ityhubhu entsha yejeli ye-bexarotene, susa ikepusi kwaye ujonge ukuba ukuvulwa kwetyhubhu kugqunywe ngetywina lokhuseleko lesinyithi. Sukuyisebenzisa ityhubhu ukuba awuliboni itywina lokhuseleko okanye ukuba itywina lityhoboziwe. Ukuba ubona itywina lokhuseleko, yijike ikepusi ijonge ezantsi kwaye usebenzise indawo ebukhali ukugqobhoza itywina.
3. Sebenzisa umnwe ococekileyo ukufaka umaleko onesisa wejel kwindawo oza kunyangwa kuphela. Lumka ungafumani nayiphi na ijeli kulusu olusempilweni olujikeleze indawo echaphazelekayo. Musa ukurabha ijeli kulusu. Kuya kufuneka ukwazi ukubona ijeli kwindawo echaphazelekayo emva kokuba ugqibile ukuyifaka.
4. Musa ukuyigubungela indawo enyangiweyo ngebhandeji eliqinileyo okanye unxibe ngaphandle kokuba uxelelwe ngugqirha ukuba wenze njalo.
5. Sula umnwe owawusebenzisa ukufaka ijeli ngethishu uze ulahle ezo zihlunu kude. Hlamba izandla zakho ngesepha namanzi.
6. Vumela ijeli ukuba yome kangangemizuzu emi-5 ukuya kwengama-10 ngaphambi kokuba ugqume ngempahla evulekileyo. Musa ukunxiba iimpahla ezixineneyo kwindawo echaphazelekayo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-bexarotene,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-bexarotene; nayiphi na enye i-retinoid efana ne-acitretin (Soriatane), etretine (Tegison), isotretinoin (Accutane), okanye tretinoin (Vesanoid); okanye naliphi na iyeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: gemfibrozil (iLopid); amanye amayeza okanye iimveliso ezisetyenziswa kulusu; kunye novithamini A (kwiivithamini ezininzi). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-bexarotene, ngoko qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. I-bexarotene yezihloko inokubangela iziphene zokuzalwa ezinzima, ke kuyakufuneka uthathe amanyathelo okuthintela ukukhulelwa ngexesha nasemva konyango lwakho. Uya kuqalisa unyango lwakho ngosuku lwesibini okanye lwesithathu lwexesha lokuya esikhathini, kwaye kuya kufuneka ukuba ube nokuvavanywa kokukhulelwa okungalunganga kwiveki enye yokuqala konyango lwakho kwaye kube kanye ngenyanga emva konyango lwakho. Kuya kufuneka usebenzise iindlela ezi-2 ezamkelekileyo zolawulo lokuzalwa ngexesha lonyango lwakho kunye nenyanga enye emva konyango lwakho. Ukuba ukhulelwa ngexesha lonyango lwakho kunye ne-bexarotene yeengqungquthela, biza ugqirha wakho ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa.
• ukuba uyindoda kwaye uneqabane elikhulelweyo okanye onokukhulelwa, thetha nogqirha wakho malunga nezinto ekufuneka uzithathile ngexesha lonyango lwakho. Shayela ugqirha wakho ngokukhawuleza ukuba iqabane lakho likhulelwe ngelixa usebenzisa i-bexarotene.
• cwangcisa ukuthintela ukuvezwa lilanga ngokungeyomfuneko kunye nokukhanya kwelanga kunye nokunxiba impahla ekhuselayo, izibuko zelanga kunye nelanga. Imixholo ye-bexarotene inokwenza ulusu lwakho lubuthathaka kwilanga.
• Sukusebenzisa izinto ezigxotha izinambuzane okanye ezinye iimveliso eziqukethe i-DEET ngexesha lonyango lwakho bexarotene.
• musa ukukrwela iindawo ezichaphazelekayo ngexesha lonyango lwakho kunye ne-bexarotene.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yegrapefruit ngelixa usebenzisa eli yeza.

Faka idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Musa ukufaka ijeli eyongezelelweyo ukwenza idosi ephosiweyo.

Imixholo ye-bexarotene inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukurhawuzelela
• ubomvu, ukutshisa, ukucaphuka, okanye ukukhawuleza kwesikhumba
• irhashalala
• intlungu
• ukubila
• ubuthathaka
• intloko ebuhlungu
• ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• umqala obuhlungu, umkhuhlane, ukugodola, okanye ezinye iimpawu zosulelo
• amadlala adumbileyo

I-Bexarotene inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifikeleleki kwaye alibonwa ngabantwana. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obugqithisileyo, amadangatye avulekileyo kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Targretin^® I-Gel yezihloko