Ambrisentan

Umxholo

• Ngaphambi kokuba uthathe i-ambrisentan,
• I-Ambrisentan inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Musa ukuthatha i-ambrisentan ukuba ukhulelwe okanye ucwangcise ukukhulelwa. I-Ambrisentan inokulimaza umbungu. Ukuba ungumfazi kwaye uyakwazi ukukhulelwa, akufuneki uqale ukuthatha i-ambrisentan de kuvavanyo lokukhulelwa lubonakalisile ukuba awukhulelwe. Kuya kufuneka usebenzise iindlela ezimbini ezinokuthenjwa zolawulo lokuzalwa ngexesha lonyango kunye neliyeza inyanga enye emva kokuyeka unyango. Musa ukwabelana ngesondo ngokungakhuselekanga. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Shayela ugqirha wakho ngokukhawuleza ukuba ulahlekelwa yinyanga okanye ucinga ukuba unokukhulelwa ngelixa uthatha i-ambrisentan.

Ngenxa yomngcipheko weziphene zokuzalwa, i-ambrisentan iyafumaneka kubantu ababhinqileyo kuphela ngenkqubo ekhethekileyo yokuhanjiswa. Inkqubo ebizwa ngokuba yi-Ambrisentan REMS (uVavanyo loMngcipheko kunye neQhinga loThintelo) sele isetelwe ukuqinisekisa ukuba isigulana sabasetyhini sineemvavanyo ezifanelekileyo zelebhu ngaphambi kwaye ngelixa zifumana i-ambrisentan. Abasetyhini banokufumana i-ambrisentan kuphela ukuba babhalisile kule nkqubo. Ugqirha wakho kufuneka akubhalise kule nkqubo. Unokufumana kuphela amayeza kwikhemesti ethatha inxaxheba kule nkqubo. Buza ugqirha wakho ukuba unemibuzo malunga nokuthatha inxaxheba kule nkqubo okanye indlela yokufumana amayeza akho.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela uvavanyo oluthile ngexesha lonyango lwakho kunye ne-ambrisentan.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-ambrisentan kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo.Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga neengozi zokuthatha i-ambrisentan.

I-Ambrisentan isetyenziswa yodwa okanye idityaniswe ne-tadalafil (Adcirca, Cialis) ukunyanga uxinzelelo lwegazi kwimiphunga (PAH, uxinzelelo lwegazi oluphezulu kwimithambo ephethe igazi ukuya emiphungeni). I-Ambrisentan inokuphucula amandla okwenza umthambo kunye nokucothisa ukwanda kweempawu kubantu abane-PAH. U-Ambrisentan ukwiklasi yamayeza abizwa ngokuba zi-endothelin receptor antagonists. Isebenza ngokumisa isenzo se-endothelin, into yendalo ebangela ukuba imithambo yegazi icuthe kwaye ithintele ukuhamba kwegazi okuqhelekileyo kubantu abane-PAH.

I-Ambrisentan iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye ngemini. Thatha i-ambrisentan malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-ambrisentan ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ugqirha wakho unokukuqala kwidosi ephantsi ye-ambrisentan kwaye ngokuthe ngcembe wandise idosi yakho.

I-Ambrisentan ilawula iimpawu ze-PAH kodwa ayiyinyangi. Qhubeka uthatha i-ambrisentan nokuba uziva uphilile. Sukuyeka ukuthatha i-ambrisentan ngaphandle kokuthetha nogqirha wakho. Ukuba ngequbuliso uyeka ukuthatha i-ambrisentan, imeko yakho inokuba mandundu.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-ambrisentan,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-ambrisentan, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-ambrisentan. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya ukuba uthatha i-cyclosporine (Gengraf, Neoral, Sandimmune). Ugqirha wakho unokufuna ukutshintsha idosi yamayeza akho okanye ukujonga ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba une-idiopathic pulmonary fibrosis (isikhumba semiphunga ngesizathu esingaziwayo). Ugqirha wakho uya kukuxelela ukuba ungathathi i-ambrisentan.
• xelela ugqirha wakho ukuba unayo okanye wakha wanayo i-anemia (isixa esisezantsi kunesiqhelo seeseli ezibomvu zegazi) okanye isifo sesibindi.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa xa uthatha i-ambrisentan.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Ambrisentan inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukugungxula
• ulusu oluthuthu
• ukubetha kwentliziyo ngokukhawuleza
• intloko ebuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuginya okanye ukuphefumla
• irhashalala
• ubunzima obungaqhelekanga
• ukudinwa kakhulu
• Ukuphelelwa ngumdla wokutya
• ukunqongophala kwamandla
• isicaphucaphu
• ukugabha
• iintlungu kwindawo ephezulu yesisu
• mthubi ulusu okanye amehlo
• Iimpawu ezinjengomkhuhlane
• ukurhawuzelela
• umchamo omnyama ngombala

Amanye amadoda athatha iyeza elifana ne-ambrisentan avelise inani elingaphantsi kwesiqhelo lobudoda (inani leeseli zokuzala); isiphumo esinokuthi sichaphazele amandla abo okuba ngutata womntwana. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-ambrisentan ukuba ungathanda ukuba nabantwana kwikamva.

I-Ambrisentan inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• intloko ebuhlungu
• ukugungxula
• isiyezi
• isicaphucaphu
• ukuxinana kwempumlo

Musa ukuvumela nabani na ukuba athathe amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ILetairis^®