Ademetionine

Umxholo

• Wenza ntoni i-ademetionine?
• Zithini iziphumo ebezingalindelekanga ze-ademetionine?
• I-ademetionine ilawulwa njani?
• Zithini izibonelelo zeademetionine?
• Buphi ubungozi be-ademetionine?
• Ngaba isigulana sikulungiselela njani ukuthatha i-ademetionine?
• Zithini iziphumo ze-ademetionine?

Yintoni ademetionine?

IAdemetionine luhlobo lweamino acid methionine. Ikwabizwa ngokuba yi-S-adenosylmethionine, okanye i-SAMe.

Ngokwesiqhelo, umzimba womntu wenza yonke i-ademetionine efunekayo kwimpilo entle. Nangona kunjalo, amanqanaba asezantsi e-methionine, folate, okanye ivithamini B-12 inokubangela ukwehla kwamanqanaba e-ademetionine. Kuba le khemikhali ayibikho ekutyeni, maxa wambi uhlobo lwendibaniselwano lusetyenziselwa ukumisa amanqanaba emzimbeni.

I-Ademetionine ithengiswa njengesongezelelo sokutya eMelika. EYurophu, isetyenziswa njengeyeza likagqirha.

Wenza ntoni i-ademetionine?

I-SAMe idlala indima kwinkqubo yamajoni omzimba, igcina inwebu yeseli, kwaye inceda ukuvelisa nokwaphula iikhemikhali zobuchopho, ezinje nge-serotonin, melatonin, kunye ne-dopamine.

Uphando olongezelelekileyo kodwa olungagqibelelanga lubonisa ukuba kunokuba luncedo ekunyangeni iimpawu ze:

• ukudakumba
• ukuqina kwesibindi
• ezingapheliyo hepatitis wentsholongwane
• i-jaundice xa ukhulelwe
• Isifo sikaGilbert
• ifibromyalgia
• iingxaki zemithambo-luvo ezinxulumene noGawulayo
• cholestasis (ibile evaliweyo ukuphuma kwisibindi ukuya kwinyongo)

Zithini iziphumo ebezingalindelekanga ze-ademetionine?

I-Ademetionine ikhuselekile kuninzi lwabantu abadala. Nangona kunjalo, ngamanye amaxesha kunokubangela iziphumo ebezingalindelekanga zilandelayo:

• irhasi
• ukuqhina
• urhudo
• ukugabha
• umlomo owomileyo
• intloko ebuhlungu
• Ukuphuthelwa kancinci
• ianorexia
• ukubila
• isiyezi
• uvalo
• irhashalala
• isifo se-serotonin

Izigulana ezinokudakumba zinokuziva zixhalabile. Isisu esibuhlungu sinokuvela xa izigulana ziqala ukuthatha olu ncediso. Ukuqala ngeedosi ezincinci kunye nokusebenza ukuya kuthi ga kwidosi epheleleyo kunokunceda umzimba uhlengahlengise.

Izigulana ezinobungozi kwi-ademetionine zinokuba neempawu zokuphendula kwe-anaphylactic. Ezi mpawu zibandakanya:

• ukugungxula okanye ukubomvu kolusu
• ukubetha
• isiyezi
• isicaphucaphu

I-ademetionine ilawulwa njani?

I-Ademetionine yenziwa ngomlomo nangomthambo. Ikliniki yaseMayo inika ingxelo yokuba la madosi alandelayo omlomo ayasebenza kubantu abadala abanezi meko zilandelayo:

• I-osteoarthritis: i-600 ukuya kwi-1,200 milligrams (mg) kwithamo enye ukuya kathathu yahlulwe yonke imihla
• cholestasis: ukuya kuthi ga kwi-1,600 mg yonke imihla
• Uxinzelelo: 800 ukuya kwi-1,600 mg yonke imihla
• i-fibromyalgia: 400 mg ithathwa kabini yonke imihla
• isifo sesibindi: i-600 ukuya kwi-1,200 mg yonke imihla

Idosi epheleleyo ye-ademetionine ihlala i-400 mg, ithathwa kathathu okanye kane amaxesha ngamaxesha.

I-Ademetionine ayithathwa njengekhuselekileyo ebantwaneni.

Zithini izibonelelo zeademetionine?

I-Ademetionine iyasebenza ekupheliseni iintlungu ze-osteoarthritis. Izibonelelo ze-ademetionine kunyango lwezinye iimeko aziqinisekanga. Obunye ubungqina bubonisa ukuba bunokunceda ukunyanga:

• ukudakumba
• Ingxaki yokungahambi kakuhle (ADHD) kubantu abadala
• cholestasis kwizigulana ezikhulelweyo nezingakhulelwanga
• ifibromyalgia
• isifo sesibindi

I-Ademitionine isetyenziselwa ukunyanga ezinye iimeko ezininzi, nangona kungekho bungqina baneleyo bokuchonga ukuba ingaba iyanceda na kwezi meko. Imiqathango yokusetyenziswa kwe-ademitionine ngamanye amaxesha ibandakanya:

• i-premenstrual syndrome (PMS)

• isifo sentliziyo
• migraine intloko ebuhlungu
• ukwenzakala emqolo
• ukuxhuzula
• isifo sokugubhuka

Buphi ubungozi be-ademetionine?

Qhagamshelana nomboneleli wezempilo ngaphambi kokuba uthathe nawaphi na amayeza, kubandakanywa imifuno kunye nezongezelelo.

I-Ademetionine ithathwa njengekhuselekileyo kuninzi lwabantu abadala. Nangona kunjalo, inokuba mandundu ngakumbi imeko kwizigulana ezinengxaki ethile, enjenge-bipolar disorder okanye isifo sika-Parkinson. Abafazi abakhulelweyo okanye abancancisayo akufuneki bathathe i-ademetionine.

Kuba ichaphazela inkqubo ye-nervous system, i-ademetionine inokuphazamisana notyando. Ukusetyenziswa kwayo kufuneka kuyekwe ubuncinci iiveki ezimbini ngaphambi kotyando.

I-Ademetionine inxibelelana ne-serotonin, ikhemikhali kwingqondo yakho. Xa zidityaniswe namayeza achaphazela i-serotonin, i-ademetionine inokunyusa umngcipheko wesifo se-serotonin. Le yimeko enokubakho enokubangelwa yi-serotonin eninzi. Iziphumo ezinokubandakanya iingxaki zentliziyo, ukungcangcazela kunye noxinzelelo.

I-Ademetionine akufuneki ithathwe ngala mayeza alandelayo:

• I-dextromethorphan (isithako esisebenzayo kumayeza amaninzi okukhohlisa)
• iziyobisi ezichasayo
  • fluoxetine
  • paroxetine
  • Unyango
  • mzantsiweb
  • clomipramine
  • imipramine
• i-monoamine oxidase inhibitors (MAOIs)
  • phenelzine
  • lwenyathi
  • meperidine (iDemerol)
  • ipentazocine
  • yerengqine

I-Ademetionine akufuneki ithathwe ngamayeza kunye nezongezo ezonyusa amanqanaba e-serotonin. Oku kubandakanya:

• ilevodopa
• IHawaiian baby woodrose
• I-Lptptophan
• Wort yaseSt

I-Ademetionine akufuneki ithathwe ngamayeza eswekile kuba anokunyusa iziphumo zala machiza. Oku kunokunyusa umngcipheko weswekile esezantsi yegazi, okanye i-hypoglycemia.

Ngaba isigulana sikulungiselela njani ukuthatha i-ademetionine?

Isisu esibuhlungu kunye neempembelelo zokugaya ukutya zinokwenzeka ukuba uqala ngethamo elicetyiswe ngokupheleleyo. Ukuqala ngeedosi ezincinci kude kube ziziphumo ebezingalindelekanga ezisezantsi zinokunceda umzimba ukuba uhlengahlengise.

Zithini iziphumo ze-ademetionine?

I-Ademetionine iluncedo ekupheliseni iintlungu ze-osteoarthritis. Kubonakala ngathi iyasebenza njengeziyobisi ezichasayo (ii-NSAIDs) ekunyangeni le meko, ngokweMayo Clinic. Nangona kunjalo, abukho ubungqina obaneleyo ekusetyenzisweni kwe-ademetionine yoxinzelelo, i-fibromyalgia, kunye ne-cholestasis yesibindi. Ulwazi oluthe kratya luyafuneka ukucebisa usetyenziso lwalo kunyango lwezi meko.