I-Bosutinib

Umxholo

• Ngaphambi kokuba uthathe i-bosutinib,
• I-Bosutinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

I-Bosutinib isetyenziselwa ukunyanga uhlobo oluthile lwe-myeloid leukemia engapheliyo (i-CML; uhlobo lomhlaza weeseli ezimhlophe zegazi), kubandakanya unyango kubantu abasandula kufunyaniswa ukuba banayo le meko nakwabo abangasenako ukuxhamla kwamanye amayeza I-CML okanye ngubani ongakwaziyo ukuthatha la mayeza ngenxa yeziphumo ebezingalindelekanga. I-Bosutinib ikudidi lwamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Bosutinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye nokutya kanye ngemini. Thatha i-bosutinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-bosutinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Ukuba kukho naziphi na iipilisi ezaphukileyo okanye ezaphukileyo, musa ukuzichukumisa ngezandla zakho.

Ugqirha wakho unokuyeka okwethutyana okanye ngokusisigxina unyango lwakho okanye uhlengahlengise idosi yakho ye-bosutinib ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Qhubeka uthathe i-bosutinib nokuba uziva uphilile. Sukuyeka ukuthatha i-bosutinib ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-bosutinib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-bosutinib okanye naziphi na izithako kwiipilisi ze-bosutinib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: izinto ezithile zokubulala ukungunda ezifana ne-ketoconazole kunye ne-itraconazole (Sporanox); Aprepitant (Hlomela); amayeza athile asetyenziselwa ukunyanga intsholongwane yokungakhuseleki komzimba (i-HIV) njenge-indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), kunye ne-saquinavir (Invirase); amayeza okunciphisa isisu esiswini (iiproton-pump inhibitors) ezinje nge-esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), kunye ne-rabeprazole (AcipHex); I-diltiazem (iCardizem, iCartia, iTiazac); i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin); nefazodone; irifabutin (Mycobutin); kunye nerifampin (Rifadin, Rimactane eRifamate, eRifater). Uninzi lwamanye amayeza anokusebenzisana ne-bosutinib, ke qiniseka ukuba uxelele ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha ii-antacids, ezifana ne-aluminium hydroxide / i-magnesium hydroxide (Maalox), i-calcium carbonate (Tums) okanye i-calcium carbonate kunye ne-magnesium (i-Rolaids) okanye amayeza okunciphisa i-asidi esiswini, njenge-cimetidine (Tagamet), i-famotidine (i-Pepcid), okanye ranitidine (Zantac), thatha iiyure ezi-2 ngaphambi okanye iiyure ezi-2 emva kokuba uthathe i-bosutinib.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe waba nezintso, isibindi, okanye isifo sentliziyo.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Uya kudinga ukuthatha uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye awufanelanga ukuba ukhulelwe ngelixa uthatha i-bosutinib. Kuya kufuneka usebenzise indlela esebenzayo yolawulo lokuzalwa ngexesha lonyango kunye ne-bosutinib kunye neeveki ezi-2 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa uthatha i-bosutinib, biza ugqirha wakho. I-Bosutinib inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa uthatha i-bosutinib kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga neengozi zokuthatha i-bosutinib.

Sukutya igrapefruit, usele ijusi yeziqhamo, okanye uthathe nasiphi na isongezo esine-grapefruit xa ukhupha la mayeza.

Thatha idosi ephosiweyo ngokutya nje ukuba ukhumbule.Nangona kunjalo, ukuba ngaphezulu kweeyure ezili-12 ukusukela kwidosi yakho yokugqibela, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Bosutinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• Ukuphelelwa ngumdla wokutya
• ukudinwa okanye ubuthathaka

• utshintsho kwisakhono sokungcamla ukutya
• kukhala ezindlebeni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• isicaphucaphu
• ukugabha
• urhudo
• intlungu yesisu ngokukhawuleza
• ukopha okungachazwanga okanye ukugruzuka
• igazi kumchamo okanye isitulo
• utshintsho rhoqo ukuchama
• ukwandisa okanye ukunciphisa inani umchamo
• isiyezi
• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
• ukuphefumla kancinci kunye nokukhohlela
• iintlungu zesifuba
• ukudumba kobuso, izandla, amaqatha, iinyawo, okanye imilenze esezantsi
• ukukhawuleza ukutyeba
• ubumthubi besikhumba namehlo
• umchamo omnyama okanye weti
• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya

I-Bosutinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-bosutinib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IBosulif^®