Glucarpidase

Umxholo

• Ngaphambi kokuba uthathe i-glucarpidase,
• I-Glucarpidase inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Glucarpidase isetyenziselwa ukuthintela iziphumo eziyingozi ze-methotrexate (Rheumatrex, Trexall) kwizigulana ezinesifo sezintso ezifumana i-methotrexate ukunyanga iintlobo ezithile zomhlaza. I-Glucarpidase ikudidi lwamayeza abizwa ngokuba zii-enzymes. Isebenza ngokunceda ukuphula kunye nokususa i-methotrexate emzimbeni.

I-Glucarpidase iza njengomgubo wokudityaniswa nolwelo kwaye itofwe ngaphakathi (emthanjeni). Ihlala inikwa ngaphezulu kwemizuzu emi-5 njengedosi yexesha elinye. I-Glucarpidase inikwa kunye ne-leucovorin (elinye iyeza elisetyenziselwa ukuthintela iziphumo eziyingozi ze-methotrexate) de uvavanyo lwebhubhoratri lubonise ukuba unyango alusafuneki.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-glucarpidase,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa kwi-glucarpidase, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-glucarpidase injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: folic acid (Folicet, kwii-multivitamini); ilevoleucovorin (Fusilev); okanye pemetrexed (Alimta). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba ufumana i-leucovorin, kufuneka inikwe ubuncinci iiyure ezi-2 ngaphambi okanye iiyure ezi-2 emva kweglucarpidase.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-glucarpidase, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Glucarpidase inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ifiva
• Ukugodola
• ukugungxula okanye ukuziva ushushu
• irhashalala
• urhwebo
• ukurhawuzelela
• ukuqina komqala okanye ukuphefumla nzima
• iimvakalelo zokuba ndindisholo, ukurhawuzelela, ukuhlaba, ukutshisa, okanye ukukhasa esikhumbeni
• intloko ebuhlungu

I-Glucarpidase inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-glucarpidase.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga ne-glucarpidase.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Voraxaze^®