Acidicholic acid

Umxholo

• Ngaphambi kokuba uthathe i-obeticholic acid,
• I-Obeticholic acid inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Obeticholic acid inokubangela ukonakala kwesibindi okanye ukusongela ubomi, ngakumbi ukuba idosi ye-obeticholic acid ayilungiswanga xa isifo sesibindi sisiba mandundu. Ukuba uhlangabezana naziphi na kwezi mpawu zilandelayo ngelixa uthatha i-obeticholic acid, tsalela umnxeba kwangoko: ubumthubi besikhumba okanye amehlo, umchamo omnyama, isitulo esimnyama sokuhlala, ukukhohlela okanye ukugabha igazi, isicaphucaphu, ukugabha, iintlungu zesisu, ukudumba ngaphakathi nakujikeleze indawo yesisu, ukwehla kobunzima, ukungabinamdla wokutya, ukudinwa, urhudo, ukudideka, intetho ekrwada, ixhala, ukutshintsha kwemozulu, utshintsho kubuntu, okanye ukuchama rhoqo.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile ngaphambi nangexesha lonyango lwakho ukujonga ukusebenza kwesibindi kunye nokuphendula komzimba wakho kwi-obeticholic acid.

I-Obeticholic acid isetyenziswa yodwa okanye idityaniswe ne-ursodiol (Actigall, Urso) ukunyanga i-biliary cholangitis (PBC; uhlobo lwesifo sesibindi esitshabalalisa i-bile ducts, evumela i-bile ukuba ihlale esibindini kwaye ibangele umonakalo) kubantu abangakwaziyo ukuthatha i-ursodiol okanye kubantu abangakhange baphathwe ngempumelelo nge-ursodiol yodwa. I-Obeticholic acid ikudidi lwamayeza abizwa ngokuba yi-farnesoid X receptor agonists. Isebenza ngokunciphisa ukuveliswa kwenyongo esibindini kunye nokwandisa ukususwa kwenyongo esibindini.

I-Obeticholic acid iza njengecwecwe lokuthatha ngomlomo. Ithathwa ngesiqhelo kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-obeticholic acid malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-obeticholic acid ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokufuna ukumisa okwexeshana okanye ngokusisigxina unyango lwakho okanye unciphise idosi ye-obeticholic acid ngexesha lonyango lwakho. Oku kuya kuxhomekeka ekusebenzeni kakuhle kweyeza okanye ukuba uneziphumo ebezingalindelekanga ezithile. Qhubeka uthathe i-obeticholic acid nokuba uziva uphilile. Sukuyeka ukuthatha i-obeticholic acid ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-obeticholic acid,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-obeticholic acid, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-obeticholic acid. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: icaffeine (efumaneka kunyango oluthile ukunyanga ukozela kunye nentloko), theophylline (Elixophyllin, Theo-24, Theochron, abanye), tizanidine (Zanaflex), okanye warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-obeticholic acid, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha icholestyramine (Prevalite), colestipol (Colestid), okanye colesevelam (Welchol), thatha ubuncinci iiyure ezi-4 ngaphambi okanye kwiiyure ezi-4 emva kwe-asidi ye-obeticholic.
• xelela ugqirha wakho ukuba unothintelo lwe-bile duct (ukuvaleka kwimibhobho ethwala inyongo ukusuka kwisibindi ukuya kwi-gallbladder kunye namathumbu amancinci). Ugqirha wakho unokukuxelela ukuba ungathathi i-obeticholic acid.
• xelela ugqirha wakho ukuba ukhe waba ne-cholesterol ephezulu okanye isifo se-thyroid.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-obeticholic acid, tsalela umnxeba ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Obeticholic acid inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• umlomo okanye umqala obuhlungu
• ngokukhawuleza, ngokungaqhelekanga, okanye ukubetha kwentliziyo
• irhashalala
• isiyezi
• isiqaqa
• ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa okanye ubuthathaka
• intlungu edibeneyo okanye yemisipha
• ukuqhina

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• ukurhawuzelela kakhulu
• umkhuhlane, ukugodola, okanye ezinye iimpawu zosulelo
• ukoma, ukucaphuka, ukuba bomvu, ukuqweqeka okanye ukuhambisa amanzi eluswini

I-Obeticholic acid inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• mthubi ulusu okanye amehlo
• umchamo omnyama ngombala
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• isicaphucaphu
• ukugabha
• ukudumba kwindawo ejikeleze isisu

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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