IDumethyl Fumarate

Umxholo

• Ngaphambi kokuba uthathe i-dimethyl fumarate,
• I-Dimethyl fumarate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-dimethyl fumarate kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

I-Dimethyl fumarate isetyenziselwa ukunyanga abantu abadala ngeendlela ezahlukeneyo ze-multiple sclerosis (MS; isifo esingasebenzi kakuhle kwimithambo-luvo kwaye abantu banokufumana ubuthathaka, ukuba ndindisholo, ukuphulukana nokulungelelaniswa kwemisipha, kunye neengxaki ngombono, intetho, kunye nolawulo lwesinyi) kubandakanya:

• I-CIS; Iimpawu zempawu zemithambo-luvo ezihlala ubuncinci iiyure ezingama-24),
• Iifom zokuphinda zibuyele kwakhona (ikhosi yesifo apho iimpawu ziyavela khona amaxesha ngamaxesha), okanye
• iifomati zesekondari eziqhubekayo (ikhosi yesifo apho ukubuyela umva kwenzeka rhoqo).

I-Dimethyl fumarate ikwiklasi yamayeza abizwa ngokuba yi-Nrf2 activators. Isebenza ngokunciphisa ukudumba kunye nokuthintela ukonakala kwemithambo-luvo kunokubangela iimpawu ze-multiple sclerosis.

I-Dimethyl fumarate iza njengokulibaziseka-ukukhutshwa (kukhupha iyeza emathunjini ukunqanda ukophulwa kwamayeza sisisu iicids) ukuthatha umlomo. Ihlala ithathwa kabini ngemini. Thatha i-dimethyl fumarate kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-dimethyl fumarate ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

I-Dimethyl fumarate ingathathwa kunye okanye ngaphandle kokutya. Nangona kunjalo, ukuba uthatha i-dimethyl fumarate ngokutya okanye nge-aspirin egalelwe i-enteric (i-325 mg okanye ngaphantsi) imizuzu engama-30 ngaphambi kokuba uthathe i-dimethyl fumarate, mancinci amathuba okuba uchukunyiswe xa unyangwa.

Ginya zonke iifomsile; musa ukuhlafuna, okanye ubatyumze. Musa ukuvula iifomsile okanye ufefe imixholo ekutyeni.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-dimethyl fumarate kwaye wandise idosi yakho emva kweentsuku ezisi-7.

I-Dimethyl fumarate inokunceda ekulawuleni i-multiple sclerosis, kodwa ayizukuyinyanga. Qhubeka uthathe i-dimethyl fumarate nokuba uziva uphilile. Sukuyeka ukuthatha i-dimethyl fumarate ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

I-Dimethyl fumarate ngamanye amaxesha isetyenziselwa ukunyanga i-psoriasis (isifo solusu apho umbala obomvu, onamaxolo wenza iindawo ezithile zomzimba). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-dimethyl fumarate,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-dimethyl fumarate, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-dimethyl fumarate. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unayo nayiphi na intsholongwane, kubandakanywa izifo eziza kwaye zihamba kunye nezifo ezingapheliyo ezingapheliyo, okanye ukuba unayo okanye unayo inkukhu yenkukhu okanye i-herpes zoster (i-shingles; i-rash engenzeka kubantu Wayenenkukhu erhangqileyo ngaphambili); okanye ubalo lweeseli ezimhlophe ezisezantsi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-dimethyl fumarate, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Dimethyl fumarate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukufudumala, ukuba bomvu, ukurhawuzelela, okanye ukutshisa kolusu
• urhudo
• isicaphucaphu
• ukugabha
• isilungulela

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, yeka ukuthatha i-dimethyl fumarate kwaye ubize ugqirha ngoko nangoko okanye ufumane unyango olungxamisekileyo:

• ubunzima bokuginya okanye ukuphefumla
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• urhwebo
• irhashalala
• ukurhawuzelela
• ukudinwa
• iingxaki zombono
• ubuthathaka kwelinye icala lomzimba okanye ubucukubhede beengalo okanye imilenze eya isiba mandundu ngokuhamba kwexesha
• utshintsho kumbono
• utshintsho kwindlela ocinga ngayo, kwimemori, okanye ekuqondeni ekhokelela ekudidekeni kunye notshintsho kubuntu
• ukukhathala kakhulu, ukulahleka kwesidlo, iintlungu kwicala lasekunene lesisu sakho, umchamo omnyama, okanye utyheli kolusu okanye lamehlo
• ubuthathaka kwelinye icala lomzimba eliba mandundu ngokuhamba kwexesha; ukungxama kweengalo okanye imilenze; utshintsho kwindlela ocinga ngayo, inkumbulo, ukuhamba, ukulinganisela, intetho, ukubona kwamehlo, okanye amandla ahlala iintsuku ezininzi; intloko; ukuxhuzula; ukudideka; okanye utshintsho kubuntu
• ukutshisa, ukurhawuzelela, ukurhawuzelela, okanye ubuntununtunu bolusu kwelinye icala lomzimba okanye ubuso ngerhashalala elibuhlungu okanye iblisters ebonakala emva kweentsuku ezininzi

I-Dimethyl fumarate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela uvavanyo lwegazi ngaphambi kokuba uqale unyango lwakho kwaye unokuyalela iimvavanyo ezithile zebhu ngexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-dimethyl fumarate.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Tecfidera^®

• I-DMF