Inaliti yeBlinatumomab

Umxholo

• Ngaphambi kokufumana inaliti ye-blinatumomab,
• Inaliti yeBlinatumomab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo esiXwayiso ESIBALULEKILEYO okanye AMANYATHELO AKHETHEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti yeBlinatumomab kufuneka inikwe kuphela phantsi kweliso likagqirha onamava ekusebenziseni amayeza e-chemotherapy.

Inaliti ye-Blinatumomab inokubangela ukusabela okunamandla, okusongela ubomi okunokuthi kwenzeke ngexesha lokufakwa kweli yeza. Tshela ugqirha wakho ukuba wakhe waphendula nge-blinatumomab okanye naliphi na elinye iyeza. Uya kufumana amayeza athile ukunceda ukuthintela ukusabela okungafunekiyo ngaphambi kokuba ufumane idosi nganye ye-blinatumomab. Ukuba uhlangabezana naziphi na kwezi mpawu zilandelayo ngexesha okanye emva kokufumana i-blinatumomab, xelela ugqirha ngoko nangoko: umkhuhlane, ukudinwa, ubuthathaka, isiyezi, intloko ebuhlungu, isicaphucaphu, ukugabha, ukugodola, irhashalala, ukudumba kobuso, ukuvutha, okanye ukuphefumla nzima. Ukuba ufumana impendulo ebukhali, ugqirha wakho uza kuyeka ukumnika kwaye anyange iimpawu zempendulo.

Inaliti ye-Blinatumomab inokubangela nokusabela okubalulekileyo, okusongela ubomi kwinkqubo ye-nervous system. Tshela ugqirha wakho ukuba ukhe waxhuzula, wabhideka, waphulukana nokulingana, okanye unengxaki yokuthetha. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: ukuxhuzula, ukungcangcazela okungalawulekiyo komzimba, ubunzima bokuthetha, intetho edikidiki, ukulahleka kwengqondo, ubunzima bokulala okanye ukulala, intloko ebuhlungu, ukudideka, okanye ukulahleka .

Thetha nogqirha wakho malunga nomngcipheko (s) wokusebenzisa inaliti ye-blinatumomab.

I-Blinatumomab isetyenziselwa abantu abadala kunye nabantwana ukunyanga iintlobo ezithile ze-lymphocytic leukemia (ZONKE; uhlobo lomhlaza weeseli ezimhlophe zegazi) olungakhange lubengcono, okanye olubuyileyo emva konyango namanye amayeza. I-Blinatumomab ikwasetyenziselwa abantu abadala kunye nabantwana ukunyanga konke okukhoyo ukuxolelwa (ukwehla okanye ukunyamalala kweempawu kunye neempawu zomhlaza), kodwa obunye ubungqina bomhlaza buhlala. I-Blinatumomab ikudidi lwamayeza abizwa ngokuba yi-bispecific T-cell ukuzibandakanya kwiintsholongwane. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

I-Blinatumomab iza njengomgubo oxutywe nolwelo ukuze ifakwe kancinci ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi esibhedlele okanye kwiziko lonyango kwaye ngamanye amaxesha ekhaya. Eli yeza linikwa ngokuqhubekayo iiveki ezi-4 zilandelwa ziiveki ezi-2 ukuya kwezi-8 xa iyeza linganikwanga. Eli xesha lonyango libizwa ngokuba ngumjikelo, kwaye umjikelo unokuphindwa xa kufuneka. Ubude bonyango buxhomekeke kwindlela ophendula ngayo kunyango.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho, utshintshe idosi yakho, okanye uyeke unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Kubalulekile ukuba uxelele ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-blinatumomab.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-blinatumomab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-blinatumomab, nawaphi na amanye amayeza, i-benzyl alcohol. okanye naziphi na ezinye izithako kwisitofu se-blinatumomab. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: cyclosporine (Gengraf, Neoral, Sandimmune) okanye warfarin (Coumadin, Jantoven). Uninzi lwamanye amayeza anokusebenzisana ne-blinatumomab, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unentsholongwane okanye ukuba unayo okanye ukhe wosuleleka uqhubeka ubuya. Kwakhona xelela ugqirha wakho ukuba wakhe wanonyango lwemitha ebuchotsheni okanye wafumana ichemotherapy okanye wakha wanesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka ukuba ube kuvavanyo lokukhulelwa ngaphambi kokuba ufumane eli yeza. Akufanele ukhulelwe ngexesha lonyango lwakho ne-blinatumomab kwaye ubuncinci iintsuku ezi-2 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neentlobo zolawulo lokuzalwa oluza kukusebenzela. Ukuba ukhulelwa ngelixa usebenzisa i-blinatumomab, biza ugqirha wakho. I-Blinatumomab inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa ufumana i-blinatumomab kwaye ubuncinci iintsuku ezi-2 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba inaliti ye-blinatumomab inokukwenza wozele. Musa ukuqhuba imoto okanye usebenzise oomatshini ngelixa ufumana eli yeza.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho. Xelela ugqirha wakho ukuba ufumene isitofu sokugonya kwezi veki zimbini zidlulileyo. Emva kwedosi yakho yokugqibela, ugqirha wakho uya kukuxelela xa kukhuselekile ukufumana isitofu sokugonya.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti yeBlinatumomab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuqhina
• urhudo
• ukutyeba kwakho
• umqolo, ukudibana, okanye iintlungu zemisipha
• ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• iintlungu kwindawo yenaliti

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kumacandelo esiXwayiso ESIBALULEKILEYO okanye AMANYATHELO AKHETHEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• iintlungu zesifuba
• ukuba ndindisholo okanye ukurhawuzelela iingalo, imilenze, izandla okanye iinyawo
• ukuqhawukelwa ngumphefumlo
• iintlungu eziqhubekayo eziqala kwindawo yesisu kodwa zinokusasazeka emqolo ezinokuthi zenzeke okanye ngaphandle kwesicefecefe kunye nokugabha
• umkhuhlane, umqala obuhlungu, ukukhohlela, kunye neminye imiqondiso yosulelo

Inaliti yeBlinatumomab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ifiva
• ukushukuma okungalawulekiyo kwilungu lomzimba
• intloko ebuhlungu

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwisitofu se-blinatumomab kunye nokunyanga iziphumo ebezingalindelekanga ngaphambi kokuba zibe qatha.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Blincyto^®