Trifluridine kunye neTipiracil

Umxholo

• Ngaphambi kokuba uthathe i-trifluridine kunye ne-tipiracil,
• I-Trifluridine kunye ne-tipiracil zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Indibaniselwano ye-trifluridine kunye ne-tipiracil isetyenziselwa ukunyanga ikholon (amathumbu amakhulu) okanye umhlaza we-rectal osasazeke kwamanye amalungu omzimba kubantu abasele bephethwe ngamanye amayeza e-chemotherapy okanye abangafumani amayeza e-chemotherapy. Umdibaniso we-trifluridine kunye ne-tipiracil ukwasetyenziselwa ukunyanga iintlobo ezithile zomhlaza wesisu okanye umhlaza obekwe kwindawo apho isisu sihlangana khona nomqala (ityhubhu phakathi komqala nesisu) ethe yanwenwela kwamanye amalungu omzimba kubantu sele efumene ezinye iindlela zonyango ezimbini zonyango. I-Trifluridine ikwiklasi yamayeza abizwa ngokuba yi-thymidine-based nucleoside analogues. Isebenza ngokumisa ukukhula kweeseli zomhlaza. I-Tipiracil ikudidi lwamayeza abizwa ngokuba yi-thymidine phosphorylase inhibitors. Isebenza ngokucotha ukonakala kwe-trifluridine ngumzimba.

Umdibaniso we-trifluridine kunye ne-tipiracil iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kabini ngemini ngokutya kangangeentsuku ezintlanu zilandelelana, kulandele ikhefu leentsuku ezi-2. Le shedyuli yeshedyuli iyaphindwa kwaye ilandelwe yikhefu leveki ezi-2. Lo mjikelo weentsuku ezingama-28 unokuphindwaphindwa ngokuxhomekeke ekubeni lisebenza njani eli yeza kunye neziphumo ozifumanayo. Thatha i-trifluridine kunye ne-tipiracil kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-trifluridine kunye ne-tipiracil ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Iitrifluridine kunye neepilisi zeetipiracil zinamandla amabini ahlukeneyo. Ugqirha wakho unokufuna ukuba uthathe indibaniselwano yamandla amabini eepilisi ukwenza idosi yakho epheleleyo. Qiniseka ukuba uyazi ukuba luhlobo ngalunye lwethebhulethi lubonakala njani kwaye uza kuthatha kangaphi nganye. Buza ugqirha wakho okanye usokhemesti ukuba unayo nayiphi na imibuzo.

Ugqirha wakho unokulibazisa unyango lwakho okanye anciphise idosi yakho ye-trifluridine kunye ne-tipiracil ngokuxhomekeke kwiziphumo ozifumanayo. Qiniseka ukuba uthetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Ungayeki ukuthatha i-trifluridine kunye ne-tipiracil ngaphandle kokuthetha nogqirha wakho.

Hlamba izandla emva kokuphatha itrifluridine kunye neetipiracil. Ukuba omnye umntu uphatha iipilisi zakho ze-trifluridine kunye ne-tipiracil, kufuneka banxibe iiglavu okanye iiglavu zelatex ukuze ulusu lwabo lungadibani neepilisi.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-trifluridine kunye ne-tipiracil,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-trifluridine kunye ne-tipiracil, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwipilisi ye-trifluridine kunye ne-tipiracil. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha.
• xelela ugqirha wakho ukuba uneminyaka engama-65 ubudala okanye ngaphezulu, okanye ukhe unesifo sesibindi okanye sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngexesha lonyango lwakho kunye ne-trifluridine kunye ne-tipiracil. Ukuba ungumfazi, kuya kufuneka ukuba ube novavanyo lokukhulelwa ngaphambi kokuba uqale unyango, kwaye kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye neenyanga ezi-6 emva kwethamo lakho lokugqibela. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba uyindoda kwaye iqabane lakho lingakhulelwa, kuya kufuneka usebenzise ikhondom ngelixa uthatha eli yeza, kunye neenyanga ezi-3 emva konyango lwakho. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana i-trifluridine kunye ne-tipiracil, biza ugqirha wakho ngokukhawuleza. I-Trifluridine kunye ne-tipiracil zinokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Ugqirha wakho uya kukuxelela ukuba ungancancisi ngexesha lonyango lwakho kunye nosuku olu-1 emva kwedosi yakho yokugqibela.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa idosi ye-trifluridine kunye ne-tipiracil, sukuthatha elinye idosi ukwenza idosi ephosiweyo. Biza ugqirha wakho malunga nemiyalelo malunga nokwenza into yedosi ephosiweyo.

I-Trifluridine kunye ne-tipiracil zinokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukulahleka kweenwele
• utshintsho kwindlela izinto ezingcamla ngayo
• Ukuphelelwa ngumdla wokutya
• izilonda zomlomo okanye ukudumba ngaphakathi emlonyeni
• ukunqongophala kwamandla
• ukudinwa kakhulu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• umkhuhlane, iintlungu emzimbeni, ukugodola, okanye ezinye iimpawu zosulelo
• isicaphucaphu, ukugabha, urhudo, okanye iintlungu zesisu eziqatha okanye ezingahambiyo
• ubuthathaka okanye ukuphefumla kancinci xa usenza umthambo
• ulusu oluthuthu
• iintlungu zesifuba
• iintlungu ngokuphefumla okunzulu
• ukhohlela igazi
• ukopha okungaqhelekanga okanye ukugruzuka

I-Trifluridine kunye ne-tipiracil zinokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni.Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Ukuba uligcinile eli chiza ngaphandle kwesikhongozeli elingeneyo, lahla onke amacwecwe angasetyenziswanga emva kweentsuku ezingama-30.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-trifluridine kunye ne-tipiracil.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuhlawulwa^®