ISofosbuvir, iVelpatasvir, kunye neVoxilaprevir

Umxholo

• Ngaphambi kokuba uthathe i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir,
• I-Sofosbuvir, velpatasvir, kunye ne-voxilaprevir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

Usenokuba bosulelwe yi-hepatitis B (intsholongwane esosulela isibindi kwaye inokubangela ukonakala kwesibindi), kodwa ungabinazo iimpawu zesi sifo. Kule meko, ukuthatha indibaniselwano ye-sofosbuvir, i-velpatasvir, kunye ne-voxilaprevir kunokunyusa umngcipheko wokuba usulelo lwakho luya kuba lukhulu okanye lusongele ubomi kwaye uya kuba neempawu. Tshela ugqirha wakho ukuba ukhe wosulelwa yintsholongwane ye-hepatitis B. Ugqirha wakho uya ku-odola uvavanyo lwegazi ukuze abone ukuba unesifo bosulelo lwe-hepatitis B. Ugqirha wakho uya kukujonga esweni usulelo lwe-hepatitis B ngexesha kunye neenyanga ezimbalwa emva konyango lwakho. Ukuba kukho imfuneko, ugqirha unokukunika amayeza ukunyanga olu sulelo ngaphambi nangexesha lonyango lwakho ngokudibanisa i-sofosbuvir, i-velpatasvir kunye ne-voxilaprevir. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva konyango lwakho, tsalela umnxeba kwangoko: ukukhathala okugqithisileyo, ukutyheli kwesikhumba okanye amehlo, ukungabinamdla wokutya, isicaphucaphu okanye ukugabha, izitulo ezimhlophe, iintlungu kwicala lasekunene kwicala lesisu, okanye umchamo omnyama.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwindibaniselwano ye-sofosbuvir, velpatasvir, kunye ne-voxilaprevir.

Thetha nogqirha wakho malunga nomngcipheko (s) wokuthatha i-sofosbuvir, i-velpatasvir, kunye ne-voxilaprevir.

Indibaniselwano yesofosbuvir, velpatasvir, kunye ne-voxilaprevir isetyenziselwa ukunyanga usulelo olungapheliyo (lwexesha elide) losulelo lwe-hepatitis C (ukudumba kwesibindi okubangelwa yintsholongwane) kubantu abadala abasele belufumene olunye unyango lwe-HCV. I-Sofosbuvir yi-non-nucleoside NS5B polymerase inhibitor. Isebenza ngokunciphisa inani le-virus ye-hepatitis C emzimbeni. IVelpatasvir yintsholongwane ye-hepatitis C (HCV) ye-NS5A inhibitor. Isebenza ngokumisa intsholongwane ebangela i-hepatitis C ukuba isasazeke emzimbeni.IVoxilaprevir ikudidi lwamayeza abizwa ngokuba yi-HCV NS3 / 4A protease inhibitors. Isebenza ngokunciphisa inani le-HCV emzimbeni.

Indibaniselwano yesofosbuvir, velpatasvir, kunye ne-voxilaprevir iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye nokutya kanye yonke imihla iiveki ezili-12. Thatha i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Qhubeka uthathe i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir nokuba uziva uphilile. Ubude bonyango lwakho buxhomekeke kwimeko yakho, ukuba uphendula njani kunyango, kwaye nokuba uneziphumo ebezingalindelekanga ezibi. Sukuyeka ukuthatha i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba u-aleji kwi-sofosbuvir, i-velpatasvir, kunye ne-voxilaprevir, nawaphi na amanye amayeza, okanye nasiphi na isithako esidibanisa i-sofosbuvir, i-velpatasvir, kunye ne-voxilaprevir tablets. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-rifampin (iRifadin, iRimactane, eRifamate, eRifater). Ugqirha wakho uya kukuxelela ukuba ungathathi i-sofosbuvir, velpatasvir, kunye ne-voxilaprevir ukuba uthatha i-rifampin.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya nayiphi na kwezi zilandelayo: amiodarone (Nexterone, Pacerone); Amayeza e-cholesterol okwehlisa amayeza (ii-statins) ezinje nge-atorvastatin (Lipitor, eCaduet), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor), simvastatin (Flolipid, Zocor, eVytorin ); icyclosporine (Gengraf, Neoral, Sandimmune); dabigatran (Pradaxa); idigoxin (Lanoxin); H₂ iibhloko ezifana ne-cimetidine (Tagamet), i-famotidine (i-Pepcid), i-nizatidine (i-Axid), kunye ne-ranitidine (i-Zantac); amayeza athile kwintsholongwane kaGawulayo (i-HIV) okanye i-immunodeficiency syndrome (i-AIDS) kubandakanya i-atazanavir (Reyataz), efavirenz (Sustiva, e-Atripla), lopinavir (e-Kaletra), tenofovir (Viread, e-Atripla, Complera, Stribild, Truvada, abanye ), kunye ne-tipranavir (Aptivus) xa ithathwa nge-ritonavir (Norvir); imatinib (Gleevec); irinotecan (Camptosar); lapatinib (iTykerb); imethotrexate (Otrexup, Rasuvo, Xatmep); mitoxantrone; irifabutin (Mycobutin); irifapentine (Priftin); amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), oxcarbazepine (Trileptal), phenobarbital, okanye phenytoin (Dilantin, Phenytek); isulfasalazine (Azulfidine); topotecan (IHycamtin); kunye ne-warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-sofosbuvir kunye ne-velpatasvir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha i-aluminium okanye i-magnesium ene-antacids (Maalox, Mylanta), thatha iiyure ezi-4 ngaphambi okanye iiyure ezi-4 emva kwe-sofosbuvir, velpatasvir, kunye ne-voxilaprevir.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe wanalo naluphi na uhlobo lwesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-sofosbuvir, i-velpatasvir, kunye ne-voxilaprevir, biza ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokutya nje ukuba ukhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Sofosbuvir, velpatasvir, kunye ne-voxilaprevir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ukudinwa
• urhudo
• ubuthathaka
• ubunzima bokulala okanye ukulala
• ukudakumba

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• irhashalala
• ukozela
• ukudideka
• ukudumba kwendawo yesisu
• ukugabha igazi okanye into ebonakala ngathi yindawo yekhofi
• mnyama, mnyama, okanye ilindle eligazi

I-Sofosbuvir, velpatasvir, kunye ne-voxilaprevir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Zonkevi^®