Enasidenib

Umxholo

• Ngaphambi kokuba uthathe i-enasidenib,
• I-Enasidenib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

I-Enasidenib inokubangela iqela elinobuzaza okanye elisongela ubomi leempawu ezibizwa ngokuba yiyantlukwano yesifo. Ugqirha wakho uya kukujonga ngononophelo ukuze abone ukuba uyayiphuhlisa na le syndrome. Ukuba unazo naziphi na kwezi mpawu zilandelayo, biza ugqirha wakho kwangoko: umkhuhlane, ukutyeba ngequbuliso, ukuncipha kokuchama, ukudumba kweengalo zakho, imilenze, intamo, umqala, okanye indawo engaphantsi kwekhwapha, ukuphefumla kancinci, ukuphefumla nzima, iintlungu zesifuba, ukukhohlela, okanye iintlungu zethambo. Kwisibonakaliso sokuqala sokuba uhlakulela isifo sokwahlukana, ugqirha wakho uya kukunika amayeza ukunyanga i-syndrome, kwaye unokukuxelela ukuba uyeke ukuthatha i-enasidenib ixesha elithile.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-enasidenib kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

I-Enasidenib isetyenziselwa ukunyanga uhlobo oluthile lwe-myeloid leukemia (AML; uhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi) eye yanzima okanye yabuya emva konyango namanye amayeza e-chemotherapy. I-Enasidenib ikudidi lwamayeza abizwa ngokuba yi-isocitrate dehydrongenase-2 (IDH2) inhibitor. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza.

I-Enasidenib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-enasidenib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-enasidenib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya amacwecwe onke ngekomityi (eyi-8 yeemilimitha) zamanzi; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uyagabha emva kokuthatha idosi ye-enasidenib, thabatha enye idosi kwangoko kwangolo suku.

Ugqirha wakho unokuyeka okwethutyana okanye ngokusisigxina unyango lwakho, ukunciphisa idosi yakho ye-enasidenib, okanye ukunyanga ngamanye amayeza kuxhomekeke kwiziphumo ozifumanayo. Qiniseka ukuba uthetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Sukuyeka ukuthatha i-enasidenib ungakhange uthethe nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-enasidenib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-enasidenib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-enasidenib. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. Akufanele ukhulelwe ngelixa uthatha i-enasidenib. Uya kudinga uvavanyo lokukhulelwa olubi ngaphambi kokuba uqale ukuthatha eli yeza. Sebenzisa ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho nge-enasidenib kunye nenyanga enye emva kwedosi yakho yokugqibela. Ukuba uyindoda kwaye iqabane lakho linokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye nenyanga enye emva kwedosi yakho yokugqibela. I-Enasidenib inokunciphisa ukusebenza kweendlela ezithile zokucwangcisa ngomlomo ukuze uthethe nogqirha wakho ngeendlela zolawulo lokuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-enasidenib, biza ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa use-enasidenib kunye nenyanga enye emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-enasidenib.

Sela amanzi amaninzi okanye olunye ulwelo yonke imihla ngexesha lonyango lwakho nge-enasidenib,

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule kwangolo suku lunye. Nangona kunjalo, ukuba sele ilusuku olulandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Enasidenib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• ukunciphisa ukutya
• utshintsho kwindlela izinto ezingcamla ngayo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• tyheli kwamehlo akho okanye ulusu
• ukuxhamla izihlunu okanye ukujija; Ukutshisa, ukujija, okanye ukurhawuzelela ulusu; ukubetha kwentliziyo ngokungaqhelekanga; okanye ukuxhuzula

I-Enasidenib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukuyisusa i-desiccant (ipakethi encinci ebandakanyiwe namayeza okufunxa ukufuma) kwisitya.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-enasidenib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Idhifa^®