Inaliti yeCopanlisib

Umxholo

• Ngaphambi kokufumana inaliti ye-copanlisib,
• Inaliti yeCopanlisib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

Inaliti yeCopanlisib isetyenziselwa ukunyanga abantu abane-follicular lymphoma (FL; umhlaza wegazi okhula kancinci) obuyileyo emva kokuphathwa kabini okanye nangaphezulu ngamanye amayeza. Inaliti yeCopanlisib ikwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukumisa okanye ukucothisa ukusasazeka kweeseli zomhlaza.

Inaliti yeCopanlisib iza njengomgubo wokudityaniswa nolwelo kwaye inikwe ngenaliti okanye ngecatheter ebekwe emthanjeni. Ihlala itofwe kancinci kwisithuba semizuzu engama-60 ngeentsuku ezili-1,8, kunye ne-15 kumjikelo wonyango lweentsuku ezingama-28.

Inaliti yeCopanlisib inokubangela uxinzelelo lwegazi ukuya kuthi ga kwiiyure eziyi-8 emva kokufakwa. Ugqirha wakho uya kujonga uxinzelelo lwegazi ngaphambi kokuba ufumane ukumiliselwa kunye neeyure ezininzi emva kokuba ukumiliselwa kugqityiwe. Ukuba ufumana naziphi na kwezi mpawu zilandelayo emva kokufumana amayeza xelela ugqirha ngokukhawuleza: isiyezi, ukuziva udiniwe, intloko ebuhlungu, okanye ukubetha kwentliziyo.

Ugqirha wakho unokunciphisa idosi yakho, alibazise okanye ayeke unyango lwakho ngenaliti ye-copanlisib, okanye akuncede ngamayeza ongezelelweyo ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-copanlisib,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-copanlisib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ye-copanlisib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo kunye neemveliso zamayeza ozithathayo okanye oceba ukuzithatha.Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: boceprevir (Victrelis); carbamazepine (Carbatrol, Equetro, Tegretol, abanye), clarithromycin (Biaxin, e Prevpac), cobicistat (Tybost, eEvotaz, Genvoya, Prezcobix, Stribild), conivaptan (Vaprisol), diltiazem (Cardizem, Cartia XT, Dilt efavirenz (Sustiva), enzalutamide (Xtandi), idelalisib (Zydelig), indinavir (Crixivan) kunye ne-ritonavir; itraconazole (Sporonox, Onmel), kunye ne-ketoconazole, lopinavir kunye ne-ritonavir (eKaletra); mitotane (Lysodren), nefazodone, nelfinavir (Viracept), nevirapine (Viramune), paritaprevir, ritonavir, ombitasvir, kunye / okanye dasabuvir (Viekira Pak); phenobarbital, phenytoin (Dilantin, Phenytek), posaconazole (Noxafil), rifabutin (Mycobutin), rifampin (Rifadine, eRifamate, Rifater), ritonavir (Norvir, e Kaletra, Technivie, Viekira Pak), Saquasevir (Saquasevir) Aptivus) kunye ne-ritonavir; kunye ne-voriconazole (Vfend). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana nenaliti ye-copanlisib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba unentsholongwane okanye ukuba unesifo eswekile egazini, isifo seswekile, imiphunga okanye iingxaki zokuphefumla, uxinzelelo lwegazi, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ucwangcise ukuba ngutata womntwana. Akufanele ukhulelwe ngelixa ufumana inaliti ye-copanlisib. Uya kudinga uvavanyo lokukhulelwa olubi ngaphambi kokuba uqale ukufumana eli yeza. Sebenzisa ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho ngenaliti ye-copanlisib kunye nenyanga e-1 emva kwedosi yakho yokugqibela. Ukuba uyindoda kwaye iqabane lakho linokukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye nenyanga e-1 emva kwedosi yakho yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana ipopanlisib, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa ufumana inaliti ye-copanlisib, kunye nenyanga e-1 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-copanlisib.

Musa ukusela ijusi ye grapefruit ngelixa ufumana eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti yeCopanlisib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• isicaphucaphu
• ukugabha
• izilonda zomlomo, izilonda, okanye iintlungu
• Ukutshisa, ukuhlaba, ukurhawuzelela, okanye ukubindeka kwesikhumba
• iintlungu phezu kwebala
• ukudumba kwempumlo, umqala, okanye umlomo
• ukunqongophala kwamandla okanye amandla

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

• ukopha okungaqhelekanga okanye ukugruzuka
• ukukhwehlela okutsha okanye okuya kusiba mandundu, ukuphefumla kancinci, okanye ukuphefumla nzima
• irhashalala; okanye obomvu, ukurhawuzelela, ukuxobuka okanye isikhumba esidumbileyo
• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
• ukuziva ulambile kakhulu okanye unxaniwe, intloko ebuhlungu, okanye ukuchama rhoqo

Inaliti yeCopanlisib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwisitofu se-copanlisib.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-copanlisib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UAliqopa^®