Eliglustat

Umxholo

• Ngaphambi kokuthatha i-eliglustat,
• I-Eliglustat inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Eliglustat isetyenziselwa ukunyanga isifo sokuqala se-Gaucher (imeko apho into enamafutha ingaphulwanga ngokwesiqhelo emzimbeni kwaye yakhele kwamanye amalungu kwaye ibangele iingxaki zesibindi, udakada, amathambo, kunye negazi) kubantu abathile. U-Eliglustat ukwiklasi yamayeza abizwa ngokuba zii-enzyme inhibitors. Isebenza ngokuthintela umzimba ekuveliseni izinto ezinamanqatha ukuze kuncinci oku kuya kwakha emzimbeni kwaye kubangele iimpawu.

I-Eliglustat iza njengepilisi yokuthatha ngomlomo. Ihlala ithathwa kanye okanye kabini yonke imihla kunye okanye ngaphandle kokutya. Thatha i-eliglustat ngeenxa zonke zexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha ukufaneleka ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Abanye abantu banokuphendula ngokwahlukileyo kwiliflatat esekwe kwilifa labo okanye ukwakheka kwemfuza. Ugqirha wakho uya kuyalela uvavanyo lwegazi ukukunceda ufumane idosi ye-eliglatat ekulungeleyo.

Ginya zonke iicapsule ngamanzi; musa ukwahlula, vula, nyibilikisa, okanye ubatyumze.

I-Eliglustat ilawula isifo seGaucher kodwa ayisinyangi. Qhubeka nokuthatha i-eliglustat nokuba uziva uphilile. Sukuyeka ukuthatha i-eliglustat ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-eliglustat,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-eliglustat, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifilisi ze-eliglustat. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amitriptyline; amayeza athile okubetha kwentliziyo okungaqhelekanga njenge-amiodarone (Nexterone, Pacerone), digoxin (Lanoxin), quinidine (eNuedexta), procainamide, kunye ne-sotalol (iBetapace, iSorine, iSotylize); ibupropion (Aplenzin, Zyban, kwiContrave); cimetidine (iTagamet); i-clarithromycin (i-Biaxin, kwi-Prevpac), i-digoxin; diltiazem (Cardizem, Tiazac, abanye); duloxetine (ICymbalta); erythromycin; i-fluconazole (iDiflucan); ifluoxetine (Prozac, Sarafem); indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), metoprolol (Toprol); nefazodone, nelfinavir (Viracept), paroxetine (Paxil); irifampin (Rifadin, Rimactane); i-ritonavir (i-Norvir, e-Kaletra, e-Viekira Pak), amayeza okubanjwa okufana ne-carbamazepine (Carbatrol, Equetro, Tegretol, abanye), phenobarbital, kunye ne phenytoin (Dilantin, Phenytek); i-sertraline (iZoloft); terbinafine (ILamisil); kunye ne-verapamil (Calan, Verelan, abanye); Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-eliglustat, ke qiniseka ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Xelela ugqirha wakho okanye usokhemesti ukuba uthatha la mayeza alandelayo: unyango lwe-enzyme olufana ne-imiglucerase (Cerezyme), taliglucerase alfa (Elelyso), okanye i-velaglucerase alfa (Vpriv). Kuya kufuneka ulinde iiyure ezingama-24 emva kwethamo lokugqibela lale mayeza angena endaweni ye-enzyme ngaphambi kokuba uqale ukuthatha i-eliglustat.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba unesifo sesibindi. Ngokusekwe kwiziphumo zovavanyo lwakho lwegazi ukumisela ukwakheka kofuzo, ugqirha wakho angakuxelela ukuba ungathathi i-eliglustat njengoko abantu abathile bengafanelekanga ukuthatha amayeza wedwa okanye ngokudibene namanye amayeza, ukuba banesifo sesibindi, okanye ukuba udibaniso lweemeko ezithile zonyango kunye namayeza.
• xelela ugqirha wakho ukuba ukhe okanye wakha wanayo i-QT syndrome (imeko eyonyusa umngcipheko wokuba nesifo sentliziyo esingaqhelekanga esinokubangela ukuba utyhafe okanye usweleke ngesiquphe), okanye olunye uhlobo lokubetha kwentliziyo okungaqhelekanga okanye ingxaki yesingqi sentliziyo, okanye ukuba unayo okanye unayo okhe wahlaselwa sisifo sentliziyo, ukusilela kwentliziyo, okanye intliziyo, okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-eliglatat, tsalela ugqirha wakho.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa uthatha eli yeza.

Ukuba uphosa idosi, thatha idosi elandelayo ngexesha eliqhelekileyo kwaye uqhubeke neshedyuli yakho yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Eliglustat inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• ubuthathaka
• intlungu edibeneyo
• intloko ebuhlungu
• migraine
• isicaphucaphu
• isilungulela
• irhasi
• umlomo nomqala obuhlungu
• urhudo
• umqolo obuhlungu
• iintlungu emilenzeni nasezingalweni
• isisu esibuhlungu
• ukukhohlela
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ukubetha kwentliziyo, isiyezi, okanye isiqaqa

I-Eliglustat inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isiyezi
• ukungazinzi
• isicaphucaphu
• ukugabha

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-eliglustat.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICerdelga^®