Encorafenib

Umxholo

• Ngaphambi kokuba uthathe i-encorafenib,
• I-Encorafenib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Encorafenib isetyenziswa kunye ne-binimetinib (Mektovi) ukunyanga iintlobo ezithile ze-melanoma (uhlobo lomhlaza wolusu) ethe yasasazeka kwamanye amalungu omzimba okanye ayinakususwa ngotyando. Isetyenziswe kunye ne-cetuximab (i-Erbitux) ukunyanga uhlobo oluthile lomhlaza wekolon kubantu abadala abasasazeke kwamanye amalungu omzimba emva kolunye unyango. I-Encorafenib ikudidi lwamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukumisa okanye ukucothisa ukusasazeka kweeseli zomhlaza.

I-Encorafenib iza njengesingxobo sokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla. Thatha i-encorafenib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-encorafenib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba uyagabha emva kokuthatha iyeza, musa ukuthatha elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho anganciphisa okanye ayeke okwethutyana okanye ngokusisigxina unyango lwakho ngokuxhomekeke ekubeni unazo naziphi na iziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-encorafenib.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-encorafenib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-encorafenib, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwii-encorafenib capsules. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza esintu} ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amiodarone (Nexterone, Pacerone), carbamazepine (Carbatrol, Teril, abanye), citalopram (Celexa), clarithromycin (Biaxin, e Prevpac), diltiazem (Cardizem, Cartia, Diltzac, others), disopyramide (Norpace), erythromycin (EES, PCE, abanye), efavirenz (Sustiva, eAtripla), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole, modafinil (Provigil), nefazodone, nelfinavir (Viracept) ), phenobarbital, phenytoin (Dilantin, Phenytek), procainamide, quinidine (eNuedexta), rifampin (Rifadin, Rimactane, eRifamate, eRifater), ritonavir (Norvir, eKaletra), sotalol (Betapace, Sotylamil), Calan, Verelan, eTarka). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-encorafenib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zamayeza ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe wanaso okanye ukhe ube nesongezelelo sexesha QT isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuqala unyango. Kuya kufuneka usebenzise ulawulo lokuzalwa olungenalo ihomoni ukukhusela ukukhulelwa ngexesha lonyango lwakho nge-encorafenib kunye nakwiiveki ezi-2 emva kwedosi yokugqibela. I-Encorafenib inokunciphisa ukusebenza kwezicwangcisi zomlomo (iipilisi zolawulo lokuzalwa), ngoko ke kubaluleke ngakumbi ukusebenzisa uhlobo olungasebenzisiyo lolawulo lokuzalwa. Thetha nogqirha wakho malunga neendlela zolawulo lokuzalwa eziza kukusebenzela. Ukuba ukhulelwe ngelixa uthatha i-encorafenib, biza ugqirha ngokukhawuleza. I-Encorafenib inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa uthatha i-encorafenib kunye neeveki ezi-2 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuzala emadodeni. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-encorafenib.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaphakathi kweeyure ezili-12 zedosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Encorafenib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• ifiva
• isicaphucaphu
• isisu esibuhlungu
• ukuqhina
• intloko ebuhlungu
• isiyezi
• ububomvu, ukudumba, ukuba ndindisholo nokuxobuka kolusu ezandleni kunye nonyawo
• ukuqina kolusu
• irhashalala
• isikhumba esomileyo
• ukulahleka kweenwele
• intlungu edibeneyo okanye yemisipha
• utshintsho kwincasa
• umqolo obuhlungu
• induna
• impumlo iyopha

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• isiyezi, ukuphelelwa ngamandla, okanye ukuziva utyhafile
• utshintsho lombono
• Utshintsho lolusu olufana nentsumpa entsha, isibabana esibuhlungu okanye sibomvu esingapholiyo, utshintsho kubungakanani okanye umbala kwimole
• ukopha okungaqhelekanga okanye ukugruzuka
• emnyama, ilindile, okanye ilindle eligazi
• ukhohlela igazi

I-Encorafenib inokubangela umngcipheko okhulayo wokuba nomhlaza, kubandakanya nomhlaza wolusu. Ugqirha wakho uza kujonga ulusu lwakho ngaphambi konyango, zonke iinyanga ezi-2 ngexesha lonyango, kwaye ukuya kuthi ga kwiinyanga ezi-6 emva kwedosi yakho yokugqibela ye-encorafenib yeempawu zomhlaza wolusu. Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

I-Encorafenib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukuyisusa i-desiccant (iarhente yokomisa) kwibhotile.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina konke ukuqeshwa nogqirha wakho, ugqirha wamehlo, kunye nelabhoratri. Ugqirha wakho uya kuyalela uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba ngaba umhlaza wakho unganyangwa na nge-encorafenib. Ugqirha wakho angayalela iimvavanyo ezithile zelebhu, kubandakanya nokuhlolwa kwamehlo, ukujonga impendulo yomzimba wakho kwi-encorafenib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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