Erdafitinib

Umxholo

• Ngaphambi kokuba uthathe i-erdafitinib,
• I-Erdafitinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, yeka ukuthatha i-erdafitinib kwaye ubize ugqirha ngoko nangoko:

I-Erdafitinib isetyenziselwa ukunyanga umhlaza we-urothelial (umhlaza wesikhumba sesinye kunye nezinye iindawo zomchamo) osasazeka kwizicubu ezikufuphi okanye amanye amalungu omzimba angenakususwa ngotyando kwaye uye wanda ngexesha okanye emva kokuphathwa nezinye amayeza e-chemotherapy. U-Erdafitinib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukucothisa okanye ukunqanda ukusasazeka kweeseli zomhlaza.

I-Erdafitinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-erdafitinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-erdafitinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uyagabha emva kokuthatha i-erdafitinib, musa ukuthatha elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho anganciphisa umthamo wakho okanye ayeke unyango lwakho okwethutyana okanye ngokusisigxina ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-erdafitinib. Sukuyeka ukuthatha i-erdafitinib ungakhange uthethe nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-erdafitinib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-erdafitinib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-erdafitinib. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-antifungals ezifana ne-fluconazole (Diflucan), itraconazole (Sporonox, Onmel, Tolsura), kunye ne ketoconazole; carbamazepine (Carbatrol, Equetro, Tegretol, nabanye); I-clarithromycin; amayeza e-HIV (njenge-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e-Kaletra, e-Viekira), kunye ne-saquinavir (Fortovase, Invirase ); metformin (Fortamet, Glucophage, kwiActoplus Met, abanye); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek;), rifampin (Rifadin, Rimactane, eRifater); kunye ne-telithromycin (Ketek). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-erdafitinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba wakhe waxelelwa ukuba unamazinga aphezulu egazi e-phosphorus okanye ukuba unayo okanye wakha wanengxaki yamehlo okanye umbono, okanye isifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba ngutata womntwana. Ukuba ungumfazi, kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho kunye nenyanga e-1 emva kwedosi yakho yokugqibela. Ukuba uyindoda, wena kunye neqabane lakho kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye ne-erdafitinib kunye nenyanga e-1 emva kwedosi yokugqibela. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-erdafitinib, biza ugqirha wakho ngokukhawuleza. U-Erdafitinib unokulimaza umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngelixa uthatha i-erdafitinib kunye nenyanga e-1 emva kwedosi yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma kubafazi. Thetha nogqirha wakho malunga neengozi zokuthatha i-erdafitinib.
• Kuya kufuneka uyazi ukuba eli yeza linokubangela amehlo owomileyo kunye nezinye iingxaki zamehlo, ezinokuba nzulu.Ugqirha wakho unokukuxelela ukuba usebenzise iinyembezi okanye iliso lokuthambisa ngexesha lonyango lwakho nge-erdafitinib.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba ukhumbula idosi ephosiweyo ngomhla obumele ukuba wawuthatha, thatha idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule ngalo mhla. Nangona kunjalo, ukuba awukhumbuli idosi ephosiweyo kude kube lusuku olulandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Erdafitinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• urhudo
• ukugabha
• ukuqhina
• izilonda emilebeni, emlonyeni, nasemqaleni
• umlomo owomileyo
• utshintsho kwincasa
• intlungu zesisu
• ukunciphisa ukutya
• ukuhla ukusinda
• ukucheba kweenwele okungaqhelekanga okanye ukulahleka kweenwele
• ifiva
• intlungu yesihlunu okanye edibeneyo
• ukutshisa ngexesha lokuchama
• ukudinwa okanye ukudinwa
• ukuqhawukelwa ngumphefumlo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu, yeka ukuthatha i-erdafitinib kwaye ubize ugqirha ngoko nangoko:

• ukungaboni kakuhle, ukulahleka kombono, okanye ezinye iinguqu ezibonakalayo
• iingxaki zenzipho okanye utshintsho
• ukurhawuzelela, ukoma, okanye ulusu
• irhashalala
• ukudumba, iintlungu, ukuba bomvu, okanye ukuxobuka kolusu ezintendeni zeenyawo

I-Erdafitinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina konke ukuqeshwa nogqirha wakho, ugqirha wamehlo, kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-erdafitinib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IBalversa^®