Istradefylline

Umxholo

• Ngaphambi kokuba uthathe i-istradefylline,
• Istradefylline inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Istradefylline isetyenziswa kunye nendibaniselwano ye-levodopa kunye ne-carbidopa (iDuopa, iRytary, iSinemet, nabanye) ukunyanga iziqendu "zokucima" (amaxesha obunzima bokuhamba, ukuhamba, nokuthetha okunokwenzeka njengoko amayeza ephela okanye engahleliwe) kubantu Isifo sikaParkinson (PD; ukuphazamiseka kwenkqubo yemithambo-luvo ebangela ubunzima ngokuhamba, ukulawula izihlunu, kunye nokulingana). Istradefylline ikudidi lwamayeza abizwa ngokuba yi-adenosine receptor antagonists. Isebenza ngokutshintsha umsebenzi wezinto ezithile zendalo kwingqondo.

Istradefylline iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla. Thatha i-istradefylline ngeenxa zonke ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha istradefylline ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-istradefylline,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-istradefylline, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-istradefylline. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: clarithromycin (Biaxin, kwi-Prevpac); ii-antifungals ezithile ezinje nge-itraconazole (Onmel, Sporanox) okanye ketoconazole; idigoxin (Lanoxin), enzalutamide (Xtandi); amayeza athile kwintsholongwane kaGawulayo (i-HIV) okanye ifunyenwe isifo se-immunodeficiency syndrome (i-AIDS) efana ne-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e Kaletra), kunye i-saquinavir (i-Invirase); imodafinil (Provigil); nefazodone; ipioglitazone (Actos, eDuetact, eOseni); irifabutin (Mycobutin); irifampin (Rifadin); amayeza athile okubanjwa afana ne-carbamazepine (Equetro, Tegretol, Teril), oxcarbazepine (Trileptal), phenobarbital, kunye ne-phenytoin (Dilantin, Phenytek); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (iMedrol) kunye ne-prednisone; okanye telithromycin (Ketek). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-istradefylline, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho kunye nosokhemisti ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi i-wort yaseSt. Akufanele uthathe i-wort yaseSt.John ngexesha lonyango lwakho nge-istradefylline.
• xelela ugqirha wakho ukuba ubukhe wanengxaki yokugula ngengqondo (imeko ebangela ubunzima ekuchazeni umahluko phakathi kwezinto okanye izimvo eziyinyani kunye nezinto okanye izimvo ezingezizo), iintshukumo zomzimba ongenakukwazi ukuzilawula, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Akufanele ukhulelwe ngelixa uthatha i-istradefylline. Kuya kufuneka usebenzise ulawulo olusebenzayo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho nge-istradefylline. Ukuba ukhulelwa ngelixa uthatha i-istradefylline, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba usebenzisa iimveliso zecuba (iisigarethi, iisigare, umbhobho wecuba, okanye ihookah [umbhobho wamanzi] icuba). Ukutshaya iimveliso zecuba kunokunciphisa ukusebenza kweli yeza.
• Kuya kufuneka uyazi ukuba abanye abantu abathathe amayeza anje nge-istradefylline baphuhlise iingxaki zokungcakaza okanye ezinye iindlela ezinamandla zokuziphatha okanye zokuziphatha ezinyanzelekileyo okanye ezingaqhelekanga kubo, njengokunyusa iminqweno yesini okanye isimilo, inkcitho engalawulwayo, okanye ukuzinkcinkca ngotywala okanye ukutya okunyanzelekileyo. Tsalela umnxeba ugqirha wakho ukuba unomdla wokungcakaza ekunzima ukuwulawula, uneminqweno enzulu, okanye awukwazi ukulawula indlela oziphethe ngayo. Xelela amalungu osapho lwakho ngalo mngcipheko ukuze bakwazi ukubiza ugqirha nokuba awuqondi ukuba ukungcakaza kwakho okanye nayiphi na eminye iminqweno enzulu okanye indlela yokuziphatha engaqhelekanga ibe yingxaki.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Istradefylline inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isiyezi
• ukuqhina
• Ukuphelelwa ngumdla wokutya
• ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukwanda okanye ukushukuma komzimba rhoqo ongenakukulawula
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho)
• ukukrokra kakhulu okanye ukuziva abantu befuna ukukwenzakalisa
• Ukukholelwa kwizinto ezingekhoyo
• Ukuziphatha gwenxa, ukuphazamiseka, okanye ukudideka

Istradefylline inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Okwangoku^®