Inalumab ye-vedotin-ejfv Inaliti

Umxholo

• Phambi kokuba ufumane inaliti ye-enfortumab vedotin-ejfv,
• Inaliti ye-Enfortumab vedotin-ejfv inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikwiCandelo LOKUQINISEKISA OKHETHEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Enfortumab vedotin-ejfv isetyenziselwa ukunyanga umhlaza we-urothelial (umhlaza welinen yesinyi kunye nezinye iinxalenye zomchamo) osasazeke kwizicwili ezikufutshane okanye kwamanye amalungu omzimba kwaye uye wanda emva konyango namanye amayeza e-chemotherapy. Inaliti ye-Enfortumab vedotin-ejfv ikudidi lwamayeza abizwa ngokuba zii-antibodies ze-monoclonal. Isebenza ngokunceda amajoni akho omzimba ukuba acothise okanye ayeke ukukhula kweeseli zomhlaza.

Inaliti ye-Enfortumab vedotin-ejfv iza njengomgubo wokudityaniswa nolwelo kwaye itofwe ngaphakathi (emthanjeni) ngaphezulu kwemizuzu engama-30 ngugqirha okanye ngumongikazi esibhedlele okanye kwiziko lonyango. Ihlala itofelwe ngeentsuku zoku-1, 8, kunye ne-15 zomjikelo weentsuku ezingama-28 ukuba ugqirha ucebisa ukuba ufumane unyango.

Ugqirha wakho unokulibazisa okanye ayeke unyango lwakho ngenaliti ye-enfortumab vedotin-ejfv, okanye akunyange ngamayeza ongezelelweyo, kuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokuba ufumane inaliti ye-enfortumab vedotin-ejfv,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-enfortumab vedotin-ejfv inaliti, nawaphi na amanye amayeza, okanye nasiphi na isithako esenziwe kwinaliti ye-enfortumab vedotin-ejfv. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: clarithromycin (Biaxin); idelalisib (iZydelig); indinavir (iCrixivan); ketoconazole (Nizoral); nefazodone; i-nelfinavir (iViracept); i-ritonavir (iNorvir, eKaletra); okanye i-saquinavir (i-Invirase). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanayo iperipheral neuropathy (uhlobo lomonakalo wemithambo-luvo obangela ukurhawuzelela, ukuba ndindisholo, kunye nentlungu ezandleni nasezinyaweni), isifo seswekile okanye iswekile ephezulu yegazi, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukhulelwe ngelixa usifumana inaliti ye-enfortumab vedotin-ejfv. Ugqirha wakho angenza uvavanyo lokukhulelwa ukuze aqiniseke ukuba awukhulelwe ngaphambi kokuba ufumane inaliti ye-enfortumab vedotin-ejfv. Ukuba ungowasetyhini, kuya kufuneka usebenzise ulawulo lokuzalwa ngexesha lonyango lwakho kunye neenyanga ezi-2 emva kwedosi yakho yokugqibela. Ukuba uyindoda, wena kunye neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye nakwiinyanga ezi-4 emva kwedosi yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana infortumab vedotin-ejfv inaliti, tsalela ugqirha wakho. Inaliti ye-Enfortumab vedotin-ejfv inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa ufumana inaliti ye-enfortumab vedotin-ejfv kunye neeveki ezi-3 ubuncinci emva kwethamo lakho lokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuzala emadodeni. Thetha nogqirha wakho malunga neengozi zokufumana inaliti ye-enfortumab vedotin-ejfv.
• Kuya kufuneka uyazi ukuba unokufumana i-hyperglycemia (inyuka kwiswekile esegazini lakho) ngelixa ufumana eli yeza, nokuba awukabinaso isifo seswekile. Xelela ugqirha wakho kwangoko ukuba unayo kwezi mpawu zilandelayo ngelixa ufumana inaliti ye-enfortumab vedotin-ejfv: ukunxanwa okugqithisileyo, ukuchama rhoqo, ukulamba kakhulu, ukungaboni kakuhle, okanye ubuthathaka. Kubaluleke kakhulu ukubiza ugqirha wakho nje ukuba ube nazo naziphi na ezi mpawu, kuba iswekile ephezulu yegazi enganyangekiyo inokubangela imeko embi ebizwa ngokuba yi ketoacidosis. I-Ketoacidosis inokuba sengozini yobomi ukuba ayinyangwa kwangoko. Iimpawu zeketoacidosis zibandakanya: umlomo owomileyo, isicaphucaphu kunye nokugabha, ukuphefumla kancinci, umphefumlo onuka iziqhamo, kunye nokwehla kwengqondo.
• Kuya kufuneka uyazi ukuba eli yeza linokubangela amehlo owomileyo kunye nezinye iingxaki zamehlo, ezinokuba nzulu. Ugqirha wakho angakuxelela ukuba usebenzise iinyembezi okanye iliso lokuthambisa ngexesha lonyango lwakho nge-enfortumab vedotin-ejfv.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti ye-Enfortumab vedotin-ejfv inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukugabha
• isicaphucaphu
• Ukuphelelwa ngumdla wokutya
• utshintsho lwencasa
• ukulahleka kweenwele
• isikhumba esomileyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zikwiCandelo LOKUQINISEKISA OKHETHEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukuqhawukelwa ngumphefumlo
• ulusu oluthuthu
• irhashalala okanye ukurhawuzelela
• ububomvu bolusu, ukudumba, umkhuhlane, okanye iintlungu kwindawo yenaliti
• ukungaboni kakuhle, ukulahleka kombono, iintlungu zamehlo okanye ubomvu, okanye olunye utshintsho olubonakalayo
• ukuba ndindisholo, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
• ubuthathaka bemisipha
• ukudinwa kakhulu okanye ukungabikho kwamandla

Inaliti ye-Enfortumab vedotin-ejfv inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-enfortumab vedotin-ejfv.

Buza usokhemesti wakho ukuba unayo nayiphi na imibuzo onayo malunga nenaliti ye-enfortumab vedotin-ejfv.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Padcev^®