Ripretinib

Umxholo

• Ngaphambi kokuthatha i-ripretinib,
• I-Ripretinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Ripretinib isetyenziselwa ukunyanga izicubu zesisu zesisu (GIST; uhlobo lwethumba olukhula esiswini, amathumbu [amathumbu], okanye umqala [ityhubhu edibanisa umqala nesisu]) kubantu abadala ababekhe bafumana amanye amayeza, kubandakanya imatinib (Gleevec). URipretinib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukucothisa okanye ukunqanda ukusasazeka kweeseli zomhlaza.

I-Ripretinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye yonke imihla kunye okanye ngaphandle kokutya. Thatha i-ripretinib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-ripretinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ukuba uhlanza emva kokuthatha i-ripretinib, ungathathi elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho unokufuna ukumisa okwexeshana okanye ngokusisigxina unyango lwakho okanye unciphise idosi yakho ye-ripretinib ngexesha lonyango lwakho. Oku kuxhomekeke ekusebenzeni kakuhle kweyeza kunye neziphumo ebezingalindelekanga ohlangabezana nazo. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho kunye ne-ripretinib.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-ripretinib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-ripretinib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-ripretinib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: ii-antifungals ezinje nge-itraconazole (Onmel, Sporanox) kunye ne-ketoconazole; carbamazepine (Carbatrol, Tegretol, Equetro, nabanye); i-clarithromycin (i-Biaxin, kwi-Prevpac); amayeza athile kwintsholongwane kaGawulayo (i-HIV) okanye ifunyenwe isifo se-immunodeficiency syndrome (i-AIDS) kubandakanya i-efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e Kaletra), kunye ne-saquinavir (Invirase) ; nefazodone; phenobarbital; phenytoin (iDilantin, iPhenytek); ipioglitazone (Actos); irifabutin (Mycobutin); kunye nerifampin (Rifadin, Rimactane, eRifamate, eRifater). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-ripretinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ukhe wakha waba noxinzelelo lwegazi okanye isifo sentliziyo.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba ngutata womntwana. Akufanele ukhulelwe ngelixa uthatha i-ripretinib. Ukuba ungumfazi, kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho kunye ne-ripretinib kunye neveki e-1 emva kwedosi yakho yokugqibela. Ukuba uyindoda, wena kunye neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye ne-ripretinib kunye ne-1 iveki emva kwethamo lakho lokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-ripretinib, biza ugqirha ngokukhawuleza. I-Ripretinib inokubangela ingozi kumntwana.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncelise ngelixa uthatha i-ripretinib kunye neveki e-1 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-ripretinib.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-ripretinib. Ugqirha wakho unokukuxelela ukuba ungathathi i-ripretinib kwiveki e-1 ngaphambi kotyando okanye inkqubo yakho kwaye uya kukuxelela xa kufuneka uqale ukuthatha amayeza kwakhona.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaba ngaphakathi kweeyure eziyi-8 zedosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo rhoqo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Ripretinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intlungu yesihlunu okanye edibeneyo
• ukulahleka kweenwele
• ulusu olomileyo okanye olurhawuzayo
• ubuthathaka
• isicaphucaphu
• isisu esibuhlungu
• ukuqhina
• urhudo
• izilonda zomlomo okanye izilonda
• intloko ebuhlungu
• ukuhla ukusinda
• Ukuphelelwa ngumdla wokutya
• ukudumba kwezihlunu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ubomvu, iintlungu, amanxeba, ukopha, okanye ukudumba ezandleni okanye ezinyaweni; okanye ukukhawuleza
• intsumpa entsha
• utshintsho kwinkangeleko yesikhumba
• ulusu lubuhlungu okanye iqhuma elibomvu elopha okanye lingapholi
• utshintsho kubungakanani okanye umbala kwimole
• ukudinwa; ukudumba kwesisu, imilenze, okanye amaqatha; ukuqhawukelwa ngumphefumlo; okanye imithambo yentamo iyaphuma

I-Ripretinib inokunyusa umngcipheko wokuba ube nomhlaza wolusu. Thetha nogqirha wakho malunga nale ngozi.

I-Ripretinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Musa ukuyisusa i-desiccant (ipakethi encinci ebandakanyiweyo kunye neepilisi ukufunxa ukufuma) kwibhotile yakho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola uvavanyo oluthile lwelebhu kwaye ujonge uxinzelelo lwegazi ukujonga impendulo yomzimba wakho kwi-ripretinib. Ugqirha wakho uya kujonga ulusu lwakho kulo naluphi na utshintsho ngaphambi nangexesha lonyango lwakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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