IHydroxyurea

Umxholo

• Ngaphambi kokuba uthathe i-hydroxyurea,
• I-Hydroxyurea inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Hydroxyurea inokubangela ukwehla okukhulu kwenani leeseli zegazi kumongo wethambo lakho. Oku kunokunyusa umngcipheko wokuba ube nosulelo olukhulu okanye ukopha. Ukuba uhlangabezana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: umkhuhlane, ukugodola, ukudinwa okugqithisileyo okanye ubuthathaka, iintlungu zomzimba, umqala obuhlungu, ukuphefumla kancinci, ukukhohlela okuqhubekayo nokuxinana, okanye ezinye iimpawu zosulelo; ukopha okungaqhelekanga okanye ukugruzuka; enegazi okanye emnyama, ilindle; okanye ukugabha igazi okanye izinto ezimdaka ezifana namabala ekofu.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile rhoqo ukujonga impendulo yomzimba wakho kwi-hydroxyurea kunye nokujonga ukuba ubalo lwegazi lwakho lwehlile na. Ugqirha wakho unokufuna ukutshintsha idosi yakho okanye akuxelele ukuba uyeke ukuthatha ihydroxyurea kangangexesha elithile ukuvumela ukubala kwegazi lakho kubuyele esiqhelweni ukuba liye lehla kakhulu.

I-Hydroxyurea inokunyusa umngcipheko wokuba uphuhlise eminye imihlaza, kubandakanya umhlaza wolusu. Cwangcisa ukunqanda ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kwaye unxibe iimpahla zokuzikhusela, iiglasi zelanga kunye nescreen selanga. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-hydroxyurea.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngehydroxyurea kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seyeza.

I-Hydroxyurea (Hydrea) isetyenziswa yodwa okanye namanye amayeza okanye unyango ngemitha ukunyanga uhlobo oluthile lwe-leukemia engapheliyo (i-CML; uhlobo lomhlaza weeseli ezimhlophe zegazi) kunye neentlobo ezithile zomhlaza wentloko nentamo (kubandakanya umhlaza womlomo , isidlele, ulwimi, umqala, iitoni kunye nezono). I-Hydroxyurea (iDroxia, Siklos) isetyenziselwa ukunciphisa ukubakho kweengxaki ezibuhlungu kunye nokunciphisa isidingo sotofelo-gazi kubantu abadala nakubantwana abaneminyaka emi-2 ubudala nangaphezulu abanesigulo se-anemia yesifo segazi (isifo segazi esizuzwe njengelifa apho iiseli ezibomvu zegazi zimile ngokungaqhelekanga [emile okwe rhengqa] kwaye ayinako ukuzisa ioksijini eyaneleyo kuwo onke amalungu omzimba). I-Hydroxyurea ikudidi lwamayeza abizwa ngokuba ziiantimetabolites. IHydroxyurea inyanga umhlaza ngokucothisa okanye ukuyeka ukukhula kweeseli zomhlaza emzimbeni wakho. I-Hydroxyurea iphatha i-sickle cell anemia ngokunceda ukuthintela ukwakheka kweeseli ezibomvu ezimile okwe rhengqa.

I-Hydroxyurea iza njengecapsule kunye necwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini ngeglasi yamanzi. Xa i-hydroxyurea isetyenziselwa ukunyanga iintlobo ezithile zomhlaza, inokuthathwa kanye ngosuku lwesithathu. Thatha ihydroxyurea malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha ihydroxyurea ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye uhlengahlengise idosi yakho yehydroxyurea ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga onokuzifumana. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Ungayeki ukuthatha i-hydroxyurea ngaphandle kokuthetha nogqirha wakho.

Ugqirha wakho uya kukuxelela ukuba uthathe elinye iyeza, i-folic acid (ivithamini), ukunciphisa ezinye zeziphumo ebezingalindelekanga zolu nyango. Thatha la mayeza ngokuchanekileyo njengoko kuyalelwe.

Ginya zonke iifomsile; ungahluleli, ungahlaleli, okanye uzityumze.

Iipilisi zehydroxyurea 1,000-mg (Siklos) zinikwe amanqaku ukuze zikwazi ukwahlulwa ngokulula zibe sisiqingatha okanye iikota ukubonelela ngeedosi ezincinci. Musa ukuphula i-hydroxyurea i-100-mg iipilisi kwiindawo ezincinci. Ugqirha wakho uza kukuxelela indlela yokwaphula iipilisi kunye nokuba zingaphi iipilisi okanye iinxalenye zethebhulethi ekufuneka uzithathile.

Ukuba awukwazi ukugwinya iipilisi ze-hydroxyurea okanye isahlulo (s) samacwecwe, unokuyichitha idosi yakho emanzini. Beka idosi yakho kwitispuni yongeze isixa esincinci samanzi. Linda malunga nomzuzu omnye ukuvumela iipilisi ukuba zinyibilike, emva koko uginye umxube kwangoko.

Kuya kufuneka unxibe iiglavu okanye iiglavu zelatex xa uphethe iicapsule okanye iipilisi ukuze ulusu lwakho lungadibani nonyango. Hlamba izandla zakho ngesepha namanzi ngaphambi nasemva kokuba uchukumise ibhotile okanye iyeza. Ukuba ihydroxyurea ingena emehlweni akho, kwangoko gungxula amehlo akho ngamanzi ubuncinci imizuzu eyi-15. Ukuba umgubo ophuma kwicapsule okanye ithebhulethi uyachitheka, wosule kwangoko ngetawuli emanzi elahlwayo. Emva koko beka itawuli kwisitya esivaliweyo, njengeplastikhi, uyilahle kumgqomo wenkunkuma apho abantwana kunye nezilwanyana zasekhaya bengenakufikelela kuzo. Coca indawo ochithe kuyo amanzi usebenzisa isicoci sesepha esilandelwa ngamanzi acocekileyo.

I-Hydroxyurea ngamanye amaxesha isetyenziselwa ukunyanga i-polycythemia vera (isifo segazi apho umzimba wakho wenza iiseli ezibomvu zegazi). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-hydroxyurea,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-hydroxyurea, nawaphi na amanye amayeza, okanye naziphi na izinto ezingasebenziyo kwiifomsile okanye iipilisi zehydroxyurea. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nakuphi na oku kulandelayo: amayeza athile e-HIV (intsholongwane yomzimba) njenge-didanosine (Videx) kunye ne-stavudine (Zerit) kunye ne-interferon (Actimmune, Avonex, Betaseron, Infergen, Intron A, nabanye). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unayo intsholongwane kaGawulayo (i-HIV), ufumene i-immunodeficiency syndrome (i-AIDS), amanqanaba aphezulu e-uric acid egazini lakho, okanye izilonda zomlenze; ukuba uphathwa okanye wakhe waphathwa ngonyango lwemitha, umhlaza chemotherapy, okanye ihemodialysis; okanye ukuba unesifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Akufanele ukhulelwe okanye uncelise ngelixa uthatha i-hydroxyurea. Kuya kufuneka ukuba ube kuvavanyo lokukhulelwa ngaphambi kokuba uqale unyango ngehydroxyurea. Ukuba ungumfazi, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngelixa uthatha i-hydroxyurea kwaye ubuncinci iinyanga ezi-6 emva kokumisa unyango lwakho. Ukuba uyindoda, wena kunye neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa olusebenzayo ngelixa nithatha ihydroxyurea kwaye ubuncinci iinyanga ezi-6 (Siklos) okanye ubuncinci unyaka omnye (iDroxia, Hydrea) emva kokuyeka unyango. Thetha nogqirha wakho malunga neendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha nasemva konyango lwakho kwaye kufuneka uqhubeke nokusebenzisa ixesha elingakanani. Ukuba ukhulelwa ngelixa uthatha i-hydroxyurea, biza ugqirha wakho ngokukhawuleza. I-Hydroxyurea inokulimaza umbungu.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuzala emadodeni. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-hydroxyurea.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Hydroxyurea inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• Ukuphelelwa ngumdla wokutya
• ukutyeba kwakho
• izilonda emlonyeni nasemqaleni
• ukuqhina
• irhashalala
• ulusu oluthuthu
• isiyezi
• intloko ebuhlungu
• ukulahleka kweenwele
• utshintsho kolusu nezikhonkwane

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukubetha kwentliziyo ngokukhawuleza
• iintlungu eziqhubekayo eziqala kwindawo yesisu kodwa zinokusasazeka ngasemva
• amanxeba emilenzeni okanye izilonda
• iintlungu, ukurhawuzelela, ukuba bomvu, ukudumba, okanye iblisters kulusu
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• ukuba ndindisholo, ukutshisa, okanye ukubetha ezandleni okanye ezinyaweni
• umkhuhlane, ukukhohlela, ukuphefumla kancinci, kunye nezinye iingxaki zokuphefumla

I-Hydroxyurea inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni nakwizilwanyana zasekhaya. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Iipilisi ezaphukileyo ezili-1,000-mg kufuneka zigcinwe kwisikhongozeli kwaye mazisetyenziswe kwisithuba seenyanga ezintathu.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• izilonda emlonyeni nasemqaleni
• iintlungu, ubomvu, ukudumba, kunye nokukala ezandleni nasezinyaweni
• ubumnyama besikhumba

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha ihydroxyurea.

Musa ukuvumela nabani na ukuba athathe amayeza akho.Abantu abangathathi i-hydroxyurea kufuneka bayeke ukuthintela amayeza okanye ibhotile enamayeza.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Droxia^®
• IHydrea^®
• Siklos^®

• Ihydroxycarbamide