Azathioprine

Umxholo

• Ngaphambi kokuba uthathe i-azathioprine,
• I-Azathioprine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko.
• Iimpawu libanda kungaquka oku kulandelayo:

I-Azathioprine inokunyusa umngcipheko wokuphuhlisa iintlobo ezithile zomhlaza, ngakumbi umhlaza wolusu kunye ne-lymphoma (umhlaza oqala kwiiseli ezilwa nosulelo). Ukuba ukhe wafakelwa izintso, kusenokubakho umngcipheko omkhulu wokuba ube nomhlaza nokuba awuyithathi i-azathioprine. Xelela ugqirha wakho ukuba wakhe wanomhlaza okanye wawuthatha okanye wakha wazithatha iiarkhylating agents ezinje ngechlambucil (Leukeran), cyclophosphamide (Cytoxan), okanye melphalan (Alkeran) yomhlaza. Ukunciphisa umngcipheko wokuba ube nomhlaza wolusu, kuthintele ukuvela elangeni ixesha elide okanye ngokungeyomfuneko kwaye unxibe impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. Xelela ugqirha wakho ngokukhawuleza ukuba ubona naluphi na utshintsho kulusu lwakho okanye nawaphi na amaqhuma okanye ubunzima naphina emzimbeni wakho.

Abanye abantu abakwishumi elivisayo nabaselula abathathe i-azathioprine bebodwa okanye nelinye iyeza elibizwa ngokuba yi-tumor necrosis factor (TNF) blocker ukunyanga isifo sikaCrohn (imeko apho umzimba uhlasela ulusu lwendlela yokugaya ebangela iintlungu, urhudo, ukunciphisa umzimba, kunye fever) okanye i-ulcerative colitis (imeko ebangela ukudumba kunye nezilonda kumngxunya wekholoni [amathumbu amakhulu] kunye ne-rectum) iphuhlise i-hepatosplenic T-cell lymphoma (HSTCL). I-HSTCL luhlobo olubi kakhulu lomhlaza oluhlala lubangela ukusweleka ngexesha elifutshane. I-Azathioprine ayikavunywa yi-Food and Drug Administration (i-FDA) kunyango lwesifo sikaCrohn okanye isifo sezilonda, kodwa oogqirha ngamanye amaxesha banokumisela i-azathioprine ukunyanga le miqathango. Ukuba ukhula kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: iintlungu zesisu; ifiva; ukwehla kobunzima obungachazwanga; ukubila ebusuku okanye ukugruzuka ngokulula okanye ukopha.

I-Azathioprine inokubangela ukwehla kwenani leeseli zomongo wethambo lakho, ezinokubangela usulelo olubi okanye olusongela ubomi. Umngcipheko wokuba inani leeseli zegazi onalo liya kuncipha liphezulu ukuba unesifo semfuza. Ugqirha wakho unokuyalela uvavanyo ngaphambi okanye ngexesha lonyango lwakho ukuze abone ukuba unalo mngcipheko. Ukuthatha amayeza athile kunokwandisa umngcipheko wokuba iiseli zakho zegazi zinciphise, ke xelela ugqirha wakho ukuba uthatha nayiphi na kwezi zinto zilandelayo: , lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), Ramipril (Altace), okanye trandolapril (Mavik); i-trimethoprim kunye ne-sulfamethoxazole (Bactrim, Septra); kunye ne-ribavirin (iCopegus, iRebetol, iVirazole). Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: ukopha okungaqhelekanga okanye ukugruzuka; ukudinwa okugqithisileyo; ulusu oluthuthu; intloko ebuhlungu; ukudideka; isiyezi; ukubetha kwentliziyo ngokukhawuleza; ubunzima bokulala; ubuthathaka; ukuqhawukelwa ngumphefumlo; kunye nomqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo. Ugqirha wakho uya kuyalela iimvavanyo ngaphambi, ngexesha, nasemva konyango lwakho ukuze ubone ukuba ngaba iiseli zakho zegazi ziyachaphazeleka yileyeza.

Thetha nogqirha wakho malunga nemingcipheko yokuthatha la mayeza.

I-Azathioprine isetyenziswa namanye amayeza ukunqanda ukwala ukufakelwa (ukuhlaselwa komzimba otyalwe ngamajoni omzimba) kubantu abafumene ukufakelwa kwezintso. Isetyenziselwa ukunyanga isifo samathambo (imeko apho umzimba uhlasela amalungu ayo, ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi) xa amanye amayeza kunye nonyango lungancedi. I-Azathioprine ikudidi lwamayeza abizwa ngokuba zii-immunosuppressants. Isebenza ngokunciphisa umsebenzi wamajoni omzimba ukuze ingayi kuhlasela ilungu elifakelweyo okanye amalungu.

I-Azathioprine iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye okanye kabini ngosuku emva kokutya. Thatha i-azathioprine ngeenxa zonke zexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-azathioprine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba uthatha i-azathioprine ukunyanga isifo samathambo, ugqirha wakho unokukuqala kwidosi esezantsi kwaye ngokuthe ngcembe wandise idosi yakho emva kweeveki ezi-6-8 kwaye ungaphindi kanye kwiiveki ezi-4. Ugqirha wakho unokunciphisa ngokuthe ngcembe idosi yakho xa imeko yakho ilawulwa. Ukuba uthatha i-azathioprin ukukhusela ukungamkelwa kwezintso, ugqirha wakho unokukuqala kwidosi ephezulu kwaye unciphise idosi yakho ngokuthe ngcembe njengoko umzimba wakho uhlengahlengisa ukufakelwa.

I-Azathioprine ilawula i-rheumatoid arthritis kodwa ayiyinyangi. Inokuthatha ukuya kuthi ga kwiiveki ezili-12 ngaphambi kokuba uve isibonelelo esipheleleyo se-azathioprine. I-Azathioprine ithintela ukukhatywa kokukhatywa kuphela ukuba uthatha amayeza. Qhubeka nokuthatha i-azathioprin nokuba uziva uphilile. Sukuyeka ukuthatha i-azathioprine ngaphandle kokuthetha nogqirha wakho.

I-Azathioprine ikwasetyenziselwa ukunyanga ulcerative colitis (imeko ebangela ukudumba kunye nezilonda kuludwe lwekholoni [amathumbu amakhulu] kunye ne-rectum) kunye nesifo sikaCrohn. Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-azathioprine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-azathioprine, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-azathioprine. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukukhankanya amayeza akhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: allopurinol (Zyloprim); ii-aminosalicylates ezinje nge-mesalamine (Apriso, Asacol, Pentasa, abanye), olsalazine (Dipentum), kunye nesulfasalazine (Azulfidine); kunye nee-anticoagulants ('igazi elincinci') njenge-warfarin (Coumadin). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ngaba unalo naluphi na uhlobo losulelo, okanye ukuba ukhe unesifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuze uqiniseke ukuba wena okanye iqabane lakho alizukukhulelwa ngelixa uthatha eli yeza. Biza ugqirha wakho ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-azathioprine. I-Azathioprine inokulimaza umbungu.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-azathioprine.
• awunalo ugonyo ngexesha okanye emva konyango ngaphandle kokuthetha nogqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Azathioprine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko.

• irhashalala
• ifiva
• ubuthathaka
• iintlungu zemisipha

Eli yeza linokubangela ezinye iziphumo ebezingalindelekanga. Fowunela ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha i-azathioprine.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• urhudo
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Azasan^®
• Imuran^®