Meclofenamate

Umxholo

• Ngaphambi kokuba uthathe i-meclofenamate,
• I-Meclofenamate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza. Ungathathi enye i-meclofenamate de uthethe nogqirha wakho.
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

[Ithunyelwe nge-10/15/2020]

Abaphulaphuli: Umthengi, uMonde, iNgcali yezeMpilo, iFarmacy

KHUPHA: I-FDA isilumkiso sokuba ukusetyenziswa kwee-NSAID malunga neeveki ezingama-20 okanye kamva xa ukhulelwe kunokubangela iingxaki ezinqabileyo kodwa ezinzima kwizintso kumntwana ongakazalwa. Oku kunokukhokelela kumanqanaba asezantsi e-amniotic fluid ejikeleze usana kunye neengxaki ezinokubakho.

Kwii-NSAID zokumisela, i-FDA ifuna utshintsho kulwazi oluchaza umngcipheko weengxaki zezintso kwiintsana ezingekazalwa ezikhokelela kumanzi aphantsi e-amniotic.

Kwii-NSAID ezingaphezulu kwekhawuntari (i-OTC) ezilungiselelwe ukusetyenziswa kubantu abadala, i-FDA iyakuhlaziya iileyibhile zeNqaku lezeziyobisi, ezifumaneka apha: http://bit.ly/2Uadlbz. Ezi iilebheli sele zilumkisa ngokuphepha ukusebenzisa ii-NSAID ngexesha leenyanga ezi-3 zokugqibela zokukhulelwa kuba amayeza anokubangela iingxaki kumntwana ongekazalwa okanye kubunzima ngexesha lokuhanjiswa. Ilebheli yeNqaku leDrugs sele icebisa abasetyhini abakhulelweyo nabancancisayo ukuba babuze umsebenzi wezonyango ngaphambi kokusebenzisa la mayeza.

Imvelaphi:

Ii-NSAID

• ludidi lwamayeza olufumanekayo ngugqirha kunye ne-OTC. Lawo ngamanye amayeza aqhelekileyo asetyenziselwa iintlungu nomkhuhlane.
• zisetyenziselwa ukunyanga iimeko zonyango ezinje ngesifo samathambo, iintlungu zokuya exesheni, iintloko, ingqele kunye nomkhuhlane.
• sebenza ngokuthintela ukuveliswa kweekhemikhali ezithile emzimbeni ezibangela ukudumba.
• zifumaneka zodwa kwaye zidityaniswe namanye amayeza. Imizekelo yee-NSAID zibandakanya i-aspirin, ibuprofen, naproxen, diclofenac, kunye ne-celecoxib.

Iziphumo ebezingalindelekanga eziqhelekileyo ze-NSAID zibandakanya: iintlungu zesisu, ukuqhina, urhudo, igesi, ukubetha kwentliziyo, isicaphucaphu, ukugabha kunye nesiyezi.

UKUQONDA:

Abasebenzisi / Izigulana

• Ukuba ukhulelwe, ungasebenzisi ii-NSAID kwiiveki ezingama-20 okanye kamva xa ukhulelwe ngaphandle kokuba ucetyiswe ngokukodwa ukuba wenze njalo ngononophelo lwempilo ngenxa yokuba la mayeza anokubangela iingxaki kusana lwakho olungekazalwa.
• Amayeza amaninzi e-OTC ane-NSAID, kubandakanya nezo zisetyenziselwa iintlungu, ukubanda, umkhuhlane kunye nokuqaqanjelwa sisisu, ke kubalulekile ukuba ufunde iilebheli zeDrug Facts, ezifumaneka ku: http://bit.ly/2Uadlbz, ukufumanisa ukuba amayeza Ii-NSAID.
• Thetha kwingcali yakho yokhathalelo lwempilo okanye usokhemesti ukuba unemibuzo okanye inkxalabo malunga nee-NSAID okanye ngawaphi amayeza anazo.
• Amanye amayeza, anje nge-acetaminophen, ayafumaneka ukunyanga iintlungu kunye nefiva ngexesha lokukhulelwa. Thetha kumachiza wakho okanye ukhathalelo lwempilo ukuze uncede uthathe isigqibo sokuba yeyiphi eyona nto ingcono.

Iingcali Zononophelo Lwempilo

• I-FDA icebisa ukuba abaqeqeshi bezempilo kufuneka banciphise ukumisela ii-NSAID phakathi kweeveki ezingama-20 ukuya kwezingama-30 zokukhulelwa kwaye kuthintelwe ukubamisela emva kweeveki ezingama-30 zokukhulelwa. Ukuba unyango lwe-NSAID luchaziwe luyimfuneko, ukunciphisa umda wokusetyenziswa kweyona dosi iphantsi esebenzayo kunye nelona xesha lifutshane linokwenzeka. Cinga ukubeka esweni kwe-ultrasound ye-amniotic fluid ukuba unyango lwe-NSAID ludlulela ngaphezulu kweeyure ezingama-48 kwaye luyeke i-NSAID ukuba kufunyenwe i-oligohydramnios. I-FDA iyalumkisa ukuba ukusetyenziswa kwee-NSAID malunga neeveki ezingama-20 zokukhulelwa okanye emva kwexesha lokukhulelwa kunokubangela ukungasebenzi kakuhle kosana olukhokelela kwi-oligohydramnios kwaye, kwezinye iimeko, ukukhubazeka kwe-neonatal renal.
• Iziphumo ezibi zibonwa, ngokomndilili, emva kweentsuku ukuya kwiiveki zonyango, nangona i-oligohydramnios ibixelwa ngokufuthi kwakamsinya emva kweeyure ezingama-48 emva kokuqaliswa kwe-NSAID.
• I-Oligohydramnios ihlala, kodwa hayi rhoqo, ibuyela umva ngokuyeka unyango.
• Iingxaki ze-oligohydramnios ezinde zinokubandakanya isivumelwano somlenze kunye nokulibaziseka kokuvuthwa kwemiphunga. Kwezinye iimeko zokumaketha emva kokungasebenzi kakuhle kwe-renal ye-renal function, iinkqubo zokuhlasela ezinje ngokutshintshiselwa utofelo-gazi okanye idialysis.
• Ukuba unyango lwe-NSAID lubonakala luyimfuneko phakathi kweeveki ezingama-20 ukuya kwezi-30 zokukhulelwa, ukunciphisa umda ekusebenziseni idosi esebenzayo kunye nexesha elifutshane kakhulu. Njengoko kuchaziwe ngoku kwiilebheli ze-NSAID, kunqande ukumisela ii-NSAID kwiiveki ezingama-30 kwaye kamva xa ukhulelwe ngenxa yomngcipheko owongezelelekileyo wokuvalwa ngaphambi kwexesha kwe-fetus ductus arteriosus.
• Ezi ngcebiso zingasentla azisebenzi kwidosi ephantsi ye-aspirin engama-81 mg emiselwe iimeko ezithile xa ukhulelwe.
• Cinga ukubeka esweni kwe-ultrasound ye-amniotic fluid ukuba unyango lwe-NSAID ludlula iiyure ezingama-48. Yiyeke i-NSAID ukuba i-oligohydramnios yenzeka kwaye ilandelwe ngokwenkqubo yezonyango.

Ngolwazi oluthe kratya ndwendwela iwebhusayithi ye-FDA apha: http://www.fda.gov/Safety/MedWatch/SafetyInformation kunye ne-http: //www.fda.gov/Drugs/DrugSafety.

Abantu abathatha ii-nonsteroidal anti-inflammatory drug (NSAIDs) (ngaphandle kwe-aspirin) ezinje nge-meclofenamate banokuba semngciphekweni omkhulu wokuhlaselwa sisifo sentliziyo okanye ukubethwa ngabantu kunabantu abangathathi la mayeza. Ezi ziganeko zinokwenzeka ngaphandle kwesixwayiso kwaye zingabangela ukufa. Lo mngcipheko unokuphakama kubantu abathatha ii-NSAID ixesha elide. Xelela ugqirha wakho ukuba wena okanye omnye umntu kusapho lwakho ukhe unesifo sentliziyo, isifo sentliziyo, okanye ukubethwa sistroke, ukuba uyatshaya, nokuba unayo okanye wakha wanayo i-cholesterol ephezulu, uxinzelelo lwegazi oluphezulu, okanye isifo seswekile. Fumana uncedo lonyango olungxamisekileyo kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: iintlungu esifubeni, ukuphefumla kancinci, ukuba buthathaka kwelinye icala okanye icala lomzimba, okanye intetho egoso.

Ukuba uya kuba nomthambo we-coronary bypass graft (CABG; uhlobo lotyando lwentliziyo), akufuneki uthathe i-meclofenamate kanye ngaphambi okanye emva kotyando.

Ii-NSAID ezinje nge-meclofenamate zinokubangela izilonda, ukuphuma kwegazi, okanye imingxunya esiswini okanye emathunjini. Ezi ngxaki zinokuvela nanini na ngexesha lonyango, zinokwenzeka ngaphandle kweempawu zesilumkiso, kwaye zinokubangela ukufa. Umngcipheko unokuphakama kubantu abathatha ii-NSAID ixesha elide, bakhulile ngeminyaka, banempilo enkenenkene, okanye basele utywala kakhulu ngelixa bethatha i-meclofenamate. Xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo: ii-anticoagulants ('blood thinner') ezifana ne-warfarin (Coumadin); iasprini; ezinye ii-NSAID ezinje nge-ibuprofen (Advil, Motrin) kunye neaproxen (Aleve, Naprosyn); okanye ii-steroids zomlomo ezifana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (Medrol), kunye ne-prednisone (Deltasone). Xelela ugqirha wakho ukuba unayo okanye wakha waba nezilonda, ukopha esiswini okanye emathunjini, okanye ezinye iingxaki zokopha. Ukuba unazo naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-meclofenamate kwaye ubize ugqirha wakho: iintlungu zesisu, isitshisa, ukugabha okunegazi okanye okujongeka njengendawo yekofu, igazi elisesitofini, okanye isitulo esimnyama nesokulinda.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kujonga iimpawu zakho ngononophelo kwaye uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-meclofenamate. Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ukuze ugqirha wakho akhuphe inani elifanelekileyo lamayeza ukunyanga imeko yakho ngomngcipheko ophantsi weziphumo ebezingalindelekanga.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-meclofenamate kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs) ukufumana isiKhokelo seyeza.

I-Meclofenamate isetyenziselwa ukunciphisa iintlungu, ukuthamba, ukudumba, kunye nokuqina okubangelwa yi-osteoarthritis (isifo samathambo esibangelwa kukuwohloka kwemigca yamalungu) kunye nesifo samathambo (isifo samathambo esibangelwa kukudumba kwethambo lamalungu). Isetyenziselwa ukunciphisa ezinye iintlobo zentlungu ethambileyo ukuya kuthi xhaxhe, kubandakanya iintlungu zokuya exesheni (iintlungu ezenzeka ngaphambili okanye ngexesha lokuya exesheni). Kwakhona kunokusetyenziselwa ukunciphisa ukuphuma kwegazi kubasetyhini abanokulahleka kwegazi ngokungaqhelekanga. I-Meclofenamate ikwiklasi yamayeza abizwa ngokuba zii-NSAID. Isebenza ngokumisa imveliso yomzimba yento ebangela iintlungu, umkhuhlane kunye nokudumba.

I-Meclofenamate iza njengecapsule ukuthatha ngomlomo. Ihlala ithathwa kathathu okanye kane ngemini ngesifo samathambo, kathathu ngemini ngokuphulukana nokuya exesheni okunzima, okanye iiyure ezi-4 ukuya kwezi-6 njengoko kufuneka iintlungu. I-Meclofenamate ingathathwa kunye nokutya okanye ubisi ukuthintela isicaphucaphu. Ukuba uthatha i-meclofenamate rhoqo, yithathe ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-meclofenamate ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba uthatha i-meclofenamate ukunciphisa ukuphuma kwegazi okunzima, ukuphuma kwegazi kufanele kunciphise ngexesha lonyango lwakho. Biza ugqirha wakho ukuba ukuphuma kwegazi kwakho akwehli okanye ukuba ufumanisa okanye ukopha phakathi kwexesha lokuya exesheni.

Ukuba uthatha i-meclofenamate ukunciphisa iimpawu zesifo samathambo, iimpawu zakho zingaqala ukuphucula kwiintsuku nje ezimbalwa. Kungathatha iiveki ezi-2 ukuya kwezi-3 okanye ngaphezulu ukuba uve isibonelelo esipheleleyo se-meclofenamate.

I-Meclofenamate ikwasetyenziselwa ukunyanga i-ankylosing spondylitis (isifo samathambo esichaphazela kakhulu umqolo), i-gouty arthritis (iintlungu ezidibeneyo ezibangelwa kukwakhiwa kwezinto ezithile kumalungu), kunye ne-psoriatic arthritis (isifo samathambo esenzeka ngesifo solusu esihlala ixesha elide. oko kubangela ukukala nokudumba). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza ukunyanga imeko yakho.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-meclofenamate,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-meclofenamate, i-aspirin, okanye ezinye ii-NSAID ezinje nge-ibuprofen (Advil, Motrin) kunye ne naproxen (Aleve, Naprosyn), nawaphi na amanye amayeza, okanye naziphi na izithako ezingasebenziyo kwiipilisi ze-meclofenamate. Buza usokhemesti wakho uluhlu lwezinto ezingasebenziyo.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: i-enzyme eguqula i-angiotensin (ACE) enjenge-benazepril (Lotensin), i-captopril (i-Capoten), i-enalapril (i-Vasotec), i-fosinopril (i-Monopril), i-lisinopril ( Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), kunye netrandolapril (Mavik); umchamo ('iipilisi zamanzi'); lithium (Eskalith, Lithobid); kunye ne-methotrexate (Rheumatrex). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha wanayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ELIBALULEKILEYO okanye isifuba, ingakumbi ukuba uhlala unezinto ezixineneyo okanye iimpumlo ezivuzayo okanye iipolyps zempumlo (ukudumba kwempumlo yempumlo); ukudumba kwezandla, iinyawo, amaqatha, okanye imilenze esezantsi; okanye isibindi okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, ngakumbi ukuba ukwinyanga ezimbalwa ezidlulileyo zokukhulelwa kwakho, uceba ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-meclofenamate, biza ugqirha wakho.
• thetha nogqirha wakho malunga nemingcipheko kunye nezibonelelo zokuthatha i-meclofenamate ukuba uneminyaka engama-75 ubudala okanye ngaphezulu. Sukuthatha la mayeza ixesha elide okanye ngedosi ephezulu kunokuba ucetyisiwe ngugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-meclofenamate.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Meclofenamate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukuqhina
• irhasi
• izilonda emlonyeni
• intloko ebuhlungu
• kukhala ezindlebeni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, okanye ezo zikhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza. Ungathathi enye i-meclofenamate de uthethe nogqirha wakho.

• ukungaboni kakuhle
• ukuzuza ubunzima obungachazwanga
• ifiva
• amadyungudyungu
• irhashalala
• ukurhawuzelela
• urhwebo
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuphefumla okanye ukugwinya
• mthubi ulusu okanye amehlo
• ukudinwa kakhulu
• ukopha okungaqhelekanga okanye ukugruzuka
• ukunqongophala kwamandla
• isicaphucaphu
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• Iimpawu ezinjengomkhuhlane
• ulusu oluthuthu
• ukubetha kwentliziyo ngokukhawuleza
• kunamafu, kucace umbala, okanye umchamo onegazi
• umqolo obuhlungu
• ukuchama kunzima okanye kubuhlungu

I-Meclofenamate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isimilo esingavakaliyo
• ukuphazamiseka
• ukuxhuzula
• ukuncipha kokuchama

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Meclodium^®¶
• Meclomen^®¶

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.