Rifampin

Umxholo

• Ngaphambi kokuba uthathe i-rifampin,
• IRifampin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

IRifampin isetyenziswa namanye amayeza ukunyanga isifo sephepha (i-TB; isifo esosulelayo esihlasela imiphunga kwaye ngamanye amaxesha namanye amalungu omzimba). IRifampin ikwasetyenziselwa ukunyanga abanye abantu abanayo I-Neisseria meningitidis (Uhlobo lwebhaktiriya olunokubangela usulelo olubi olubizwa ngokuba yi-meningitis) kwiimpumlo okanye emqaleni. Aba bantu abanazo iimpawu zesi sifo, kwaye olu nyango lusetyenziselwa ukubathintela ukuba bosulele abanye abantu. I-Rifampin akufuneki isetyenziselwe ukunyanga abantu abaphuhlise iimpawu ze-meningitis. URifampin ukwiklasi yamayeza abizwa ngokuba ziiantimycobacterials. Isebenza ngokubulala iintsholongwane ezibangela usulelo.

Amayeza okubulala iintsholongwane afana ne-rifampin awusebenzi kwimikhuhlane, umkhuhlane, okanye ezinye izifo zentsholongwane. Ukusebenzisa i-antibiotics xa kungadingeki kwandisa umngcipheko wokufumana usulelo kamva oluchasayo unyango lwe-antibiotic.

I-Rifampin iza njengecapsule ukuyithatha ngomlomo. Kufuneka ithathwe ngeglasi epheleleyo yamanzi kwisisu esingenanto, iyure eli-1 ngaphambi okanye iiyure ezi-2 emva kwesidlo. Xa i-rifampin isetyenziselwa ukunyanga isifo sephepha, ithathwa kanye yonke imihla. Xa i-rifampin isetyenziselwa ukuthintela ukusasazeka kwe I-Neisseria meningitidis Iibhaktheriya kwabanye abantu, ithathwa kabini imihla ngemihla iintsuku ezimbini okanye kanye ngosuku iintsuku ezi-4. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-rifampin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Tshela ugqirha wakho okanye usokhemesti ukuba awukwazi ukugwinya njengezingxobo. Usokhemesti wakho unokulungiselela ulwelo ukuze uluthathe endaweni yalo.

Ukuba uthatha i-rifampin ukunyanga isifo sephepha, ugqirha wakho angakuxelela ukuba uthathe i-rifampin kangangeenyanga okanye nangaphezulu. Qhubeka uthathe i-rifampin de ugqibe amayeza nokuba uziva ungcono, kwaye ulumke ungaphoswa ziidosi. Ukuba uyeka ukuthatha i-rifampin kwakamsinya, usulelo lwakho alunakunyangwa ngokupheleleyo kwaye ibhaktiriya inokunganyangeki kwiintsholongwane. Ukuba uyaphoswa yimithamo ye-rifampin, unokuhlakulela ukungonwabi okanye iimpawu ezinzima xa uqala ukuthatha amayeza kwakhona.

I-Rifampin ngamanye amaxesha isetyenziselwa ukunyanga usulelo olubangelwa zezinye iintlobo zebhaktiriya kunye nokuthintela usulelo kubantu abebekufuphi nabantu abanezifo ezithile ezinobuzaza. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-rifampin,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-rifampin, i-rifabutin (i-Mycobutin), i-rifapentine (i-Priftin), nawaphi na amanye amayeza, okanye naziphi na izithako ezikwii-capsule ze-rifampin. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
• xelela ugqirha wakho ukuba ngaba uthatha nawaphi na amayeza alandelayo: (Invirase) zithathiwe kunye. Ugqirha wakho uya kukuxelela ukuba ungathathi i-rifampin ukuba uthatha naliphi na kula mayeza. Ukuba uthatha i-rifampin kwaye kufuneka uthathe i-praziquantal (i-Biltricide), kuya kufuneka ulinde iiveki ezi-4 ubuncinci emva kokuba uyeke ukuthatha i-rifampin ngaphambi kokuba uqale ukuthatha ipraziquantel.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin, Jantoven); ii-antifungals ezinjenge fluconazole (Diflucan), itraconazole (Onmel, Sporanox), kunye ne ketoconazole; atovaquone (Mepron, eMalarone); i-barbiturates efana ne-phenobarbital; ii-beta blockers ezinje nge-atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), kunye nepropranolol (Inderal, Innopran); iicalcium block blockers ezinjenge diltiazem (Cardizem, Cartia, Tiazac), nifedipine (Adalat, Procardia), kunye neverapamil (Calan, Verelan); ichloramphenicol; i-clarithromycin (i-Biaxin); icyclosporine (Gengraf, Neoral, Sandimmune); idaclatasvir (iDaklinza); dapsone; diazepam (Valium); doxycycline (Monodox, Oracea, Vibramycin); I-efavirenz (iSustiva); enalapril (Vaseretic); i-fluoroquinolone antibiotics njenge-ciprofloxacin (Cipro) kunye ne-moxifloxacin (Avelox); gemfibrozil (iLopid); haloperidol (iHaldol); izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, okanye inaliti); Unyango lwehomoni (HRT); indinavir (iCrixivan); irinotecan (Camptosar); i-isoniazid (kwiRifater, eRifamate); levothyroxine (Levoxyl, Synthroid, Tirosint); losartan (uCozaar); amayeza okubetha kwentliziyo ngokungaqhelekanga njenge-digoxin (Lanoxin), disopyramide (Norpace), mexiletine, propafenone (Rythmol), kunye nequinidine (eNuedexta); amayeza okuxhuzula anje nge phenytoin (Dilantin, Phenytek); imethadone (iDolophine, iMethadose); amayeza e-narcotic kwiintlungu ezinjenge-oxycodone (i-Oxaydo, i-Xtampza) kunye ne-morphine (yaseKadian); I-ondansetron (iZofran, iZuplenz); amayeza omlomo eswekile efana ne-glipizide (Glucotrol), glyburide (Diabeta), kunye ne-rosiglitazone (Avandia); probenecid (Unobumba); ikwinine (iQualquin); simvastatin (Flolipid, Zocor), ii-steroids ezinje nge-dexamethasone (i-Decadron), i-methylprednisolone (Medrol), kunye ne-prednisone; isofosbuvir (Sovaldi); tamoxifen (Soltamox); ukuqaqanjelwa (Fareston); i-trimethoprim kunye ne-sulfamethoxazole (Bactrim, Septra); itacrolimus (Prograf); i-theophylline (i-Elixophyllin, i-Theo-24); i-tricyclic antidepressants efana ne-amitriptyline kunye ne-nortriptyline (Pamelor); i-zidovudine (i-Retrovir, kwi-Trizivir), kunye ne-zolpidem (Ambien). Uninzi lwamanye amayeza anokusebenzisana ne-rifampin, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha ii-antacids, thatha i-rifampin okungenani iyure enye ngaphambi kokuba uthathe ii-antacids.
• xelela ugqirha wakho ukuba uthatha okanye usebenzisa izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi, ukufakelwa kunye nenaliti). URifampin unokunciphisa ukusebenza kwezicwangcisi zehomoni. Kuya kufuneka usebenzise enye indlela yolawulo lokuzalwa ngelixa usela la mayeza. Thetha nogqirha wakho malunga nolawulo lokuzalwa ngelixa uthatha i-rifampin.
• xelela ugqirha wakho ukuba ukhe unesifo seswekile, i-porphyria (imeko apho izinto ezithile zendalo zakha emzimbeni kwaye zinokubangela iintlungu zesisu, utshintsho kwindlela ocinga ngayo kunye nokuziphatha, okanye ezinye iimpawu), nayiphi na imeko echaphazela i-adrenal gland yakho ( ndlala encinci ecaleni kwesintso esivelisa izinto zendalo) okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-rifampin, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba unxiba iilensi zonxibelelwano ezithambileyo. I-Rifampin inokubangela amabala abomvu ngokusisigxina kwiilensi zakho zonxibelelwano ukuba uzinxiba ngexesha lonyango lwakho nge-rifampin.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ungaphoswa ngamayeza erifampin. Iidosi ezingekhoyo zinokunyusa umngcipheko wokuba uya kuba neziphumo ebezingalindelekanga ezibi. Ukuba uphose idosi, thatha idosi ephosiweyo kwakamsinya nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye ubize ugqirha wakho. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IRifampin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• Ukutshintsha kombala okwethutyana (omthubi, obomvu-orenji, okanye umbala omdaka) kulusu lwakho, amazinyo, amathe, umchamo, isitulo, ukubila kunye neenyembezi)
• ukurhawuzelela
• ukugungxula
• intloko ebuhlungu
• ukozela
• isiyezi
• ukunqongophala kolungelelwaniso
• ubunzima bokugxila
• ukudideka
• utshintsho kwindlela yokuziphatha
• ubuthathaka bemisipha
• ukuba ndindisholo
• iintlungu ezingalweni, ezandleni, ezinyaweni okanye emilenzeni
• isilungulela
• isisu esiswini
• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• urhudo
• irhasi
• iintlungu okanye iintlungu zokuya exesheni
• utshintsho lombono

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

• Izitulo ezinamanzi okanye ezinegazi, isisu, okanye umkhuhlane ngexesha lonyango okanye ukuya kuthi ga kwiinyanga ezimbini nangaphezulu emva kokuyeka unyango
• irhashalala; imihlathi ifiva; Ukugodola; ukudumba kwamehlo, ubuso, imilebe, ulwimi, okanye umqala; ubunzima bokuginya okanye ukuphefumla; ukuqhawukelwa ngumphefumlo; ukuvutha; ukudumba kwamalungu enkovu; umqala obuhkungu; iliso elipinki; iimpawu ezinjengomkhuhlane; ukopha okungaqhelekanga okanye ukugruzuka; ukudumba ngokudibeneyo okanye iintlungu
• isicaphucaphu, ukugabha, ukungabi namdla wokutya, umchamo omnyama, okanye ukuba tyheli kolusu okanye kwamehlo

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

IRifampin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• isisu esibuhlungu
• ukurhawuzelela
• intloko ebuhlungu
• ukulahleka kwengqondo
• mthubi ulusu okanye amehlo
• umbala omdaka ngombala nolusu, amathe, umchamo, ilindle, ukubila kunye neenyembezi
• Ukuthantamisa kwinxalenye ephezulu yesisu
• ukudumba kwamehlo okanye kobuso
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• ukuxhuzula

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-rifampin.

Phambi kokuba uvavanywe elebhu, kubandakanya novavanyo lweziyobisi, xelela abasebenzi ukuba uthatha i-rifampin. I-Rifampin inokubangela iziphumo zovavanyo oluthile lokuvavanywa kweziyobisi ukuba zibe ntle nangona ungakhange uwathathe amayeza.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• IRifadin^®
• Rimactane^®

• Ukuhlaziya^® (Iqulethe i-Isoniazid, Rifampin)
• Umjikelo^® (Iqulethe i-Isoniazid, Pyrazinamide, Rifampin)