I-Etidronate

Umxholo

• I-Etidronate ayinakusebenza ngokufanelekileyo kwaye inokonakalisa umqala (ityhubhu edibanisa umlomo nesisu) okanye ibangele izilonda emlonyeni ukuba ayithathiwe ngokwale miyalelo ilandelayo. Xelela ugqirha wakho ukuba awuqondi, awucingi ukuba uyakukhumbula, okanye awungekhe ukwazi ukulandela le miyalelo:
• Ngaphambi kokuba uthathe i-etidronate,
• I-Etidronate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Etidronate isetyenziselwa ukunyanga isifo sikaPaget samathambo (imeko apho amathambo ethambile kwaye ebuthathaka kwaye anokukhubazeka, ababuhlungu, okanye aphuke ngokulula) kunye nokukhusela nokunyanga i-heterotopic ossification (ukukhula kwamathambo ethambo kwindawo yomzimba ngaphezu kwamathambo) kubantu abaye bahlinzwa ngokupheleleyo (ukutshintshwa ukuze bathathe indawo yokudibanisa i-hip kunye ne-joint joint) okanye kubantu abaye balimala kwintambo yomgogodla. I-Etidronate ikwiklasi yamayeza abizwa ngokuba yi-bisphosphonates. Isebenza ngokunciphisa ukonakala kwethambo elidala kunye nokwenziwa kwethambo elitsha.

I-Etidronate iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini kwisisu esingenanto. Unyango lwesifo sikaPaget sinokuphindwa ukuba iimpawu zibuya okanye zisiba mbi emva kwexesha elidlulileyo. Thatha i-etidronate ejikeleze ixesha elifanayo (ii) yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-etidronate ngokuchanekileyo njengoko kuyalelwe. Sukuyithatha ngaphezulu okanye ngaphantsi okanye uyithathe rhoqo okanye ixesha elide kunokuba umiselwe ngugqirha.

I-Etidronate ayinakusebenza ngokufanelekileyo kwaye inokonakalisa umqala (ityhubhu edibanisa umlomo nesisu) okanye ibangele izilonda emlonyeni ukuba ayithathiwe ngokwale miyalelo ilandelayo. Xelela ugqirha wakho ukuba awuqondi, awucingi ukuba uyakukhumbula, okanye awungekhe ukwazi ukulandela le miyalelo:

• Ginya amacwecwe ngeglasi epheleleyo (eyi-6 ukuya kwi-8 yee-ounces (i-180 ukuya kwi-240 mL) yamanzi angenanto xa uhleli okanye umi.
• Hlala okanye ume nkqo emva kokuthatha i-etidronate.
• Musa ukutya, usele, okanye uthathe naliphi na iyeza (kubandakanya iivithamini okanye ii-antacids) iiyure ezi-2 ngaphambili kunye neeyure ezi-2 emva kokuba uthathe i-etidronate.

Ukuba uthatha i-etidronate ukunyanga isifo sePaget samathambo okanye ukuthintela okanye ukunyanga i-heterotopic ossification, kungathatha ixesha ukuba imeko yakho iphuculwe. Sukuyeka ukuthatha i-etidronate ungakhange uthethe nogqirha wakho.

I-Etidronate ikwasetyenziswa ngamanye amaxesha ukunyanga nokukhusela i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye abuthathaka kwaye angophuka ngokulula) ngenxa ye-corticosteroids (uhlobo lonyango olunokubangela i-osteoporosis). Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-etidronate,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-etidronate, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-etidronate. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: ii-anticoagulants (’izinciphisi zegazi’) ezifana ne-warfarin (Coumadin, Jantoven); umhlaza chemotherapy; kunye nee-steroids zomlomo ezinje nge-dexamethasone, methylprednisolone (Medrol), kunye ne-prednisone (iRayos). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• ukuba uthatha i-vitamin kunye ne-mineral supplements ezifana ne-iron, okanye ukuba uthatha i-antacids equkethe i-calcium, i-magnesium, okanye i-aluminium (i-Maalox, i-Mylanta, i-Tums, abanye), thatha iiyure ezimbini ngaphambi okanye kwiiyure ezimbini emva kokuba uthathe i-etidronate.
• xelela ugqirha wakho ukuba unazo okanye ukhe waba neengxaki kwisophagus yakho efana nokuqina kwesophageal (ukunciphisa isophagus okubangela ukuginya ubunzima) okanye achalasia (ukuphazamiseka okuchaphazela amandla esophagus ukuhambisa ukutya kwisisu), okanye i-osteomalacia (ukuthamba kwamathambo ngenxa yokunqongophala kwezimbiwa). Ugqirha wakho unokukuxelela ukuba ungathathi i-etidronate.
• xelela ugqirha wakho ukuba awukwazi ukuhlala okanye ukuma nkqo kwaye ukuba unayo okanye wakhe wanayo i-anemia (imeko apho iiseli ezibomvu zegazi zingazisi ioksijini eyaneleyo kuwo onke amalungu omzimba); inqanaba eliphantsi le-calcium egazini lakho; ubunzima bokuginya, ukutsha, izilonda, okanye ezinye iingxaki zesisu; umhlaza; i-enterocolitis (ukudumba emathunjini); naluphi na uhlobo losulelo, ngakumbi emlonyeni wakho; iingxaki ngomlomo, ngamazinyo, okanye ngeentsini; nayiphi na imeko emisa igazi lakho ekunqandeni ngesiqhelo; okanye isifo sezintso. Ugqirha wakho unokufuna ukutshintsha idosi yamayeza akho okanye ukujonga ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Xelela ugqirha wakho ukuba ucwangcisa ukukhulelwa nanini na kwixa elizayo kuba i-etidronate inokuhlala emzimbeni wakho iminyaka emva kokuyeka ukuyithatha. Biza ugqirha wakho ukuba ukhulelwe ngexesha okanye emva konyango lwakho kunye neetronronate.
• Kuya kufuneka uyazi ukuba i-etidronate inokubangela i-osteonecrosis yomhlathi (ONJ, imeko enzima yethambo lomhlathi), ngakumbi ukuba uqhaqho lwamazinyo okanye unyango ngelixa uthatha amayeza. Ugqirha wamazinyo kufuneka ahlolisise amazinyo akho kwaye enze naluphi na unyango olufunekayo, kubandakanya ukucoca okanye ukulungisa amazinyo afakelweyo ngendlela engeyiyo, ngaphambi kokuba uqale ukuthatha i-etidronate. Qiniseka ukuba uhlamba amazinyo kwaye ucoce umlomo ngokufanelekileyo ngelixa uthatha i-etidronate. Thetha nogqirha wakho ngaphambi kokuba ufumane unyango lwamazinyo ngelixa uthatha eli yeza.
• Kuya kufuneka uyazi ukuba i-etidronate inokubangela amathambo aqatha, izihlunu, okanye iintlungu ezidibeneyo. Ungaqala ukuziva le ntlungu ngaphakathi kweentsuku, iinyanga, okanye iminyaka emva kokuba uqale uthathe i-etidronate. Nangona olu hlobo lwentlungu lungaqala emva kokuba uthathe i-etidronate kangangexesha elithile, kubalulekile kuwe nogqirha wakho ukuba niqonde ukuba kunokubangelwa yi-etidronate. Biza ugqirha wakho ngoko nangoko ukuba ufumana iintlungu ezinzima nangaliphi na ixesha ngexesha lonyango lwakho kunye neetronronate. Ugqirha wakho unokukuxelela ukuba uyeke ukuthatha i-etidronate kwaye iintlungu zakho zinokuhamba emva kokuba uyekile ukuthatha iyeza.

Kubalulekile ukuba ufumane ikhalsiyam eyaneleyo kunye novithamini D kwaye utye ukutya okunesondlo ngelixa uthatha i-etidronate. Ugqirha wakho uya kukuxelela ukuba kukuphi ukutya okuyimithombo elungileyo yezi zondlo kunye nokuba zingaphi iinkonzo ozidingayo ngosuku ngalunye. Ukuba ukufumanisa kunzima ukutya oku kutya ngokwaneleyo, xelela ugqirha wakho. Kwimeko apho, ugqirha wakho unokumisela okanye acebise isongezelelo.

Ukuba awukatyi, thabatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Ukuba sele utyile, thatha idosi ephosiweyo kwiiyure ezi-2 emva kokuba ugqibe ukutya. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Etidronate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• urhudo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

• isitshisa esitsha okanye esibi
• intlungu xa uginya
• iintlungu zesifuba
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• kunzima ukugwinya
• Amadyungudyungu kulusu

I-Etidronate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukugabha
• isisu esiswini
• urhudo
• iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni
• ukuxhamla izihlunu kunye neekram

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-etidronate.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Idronron^®

• I-EHDP