Ingcambu yedesmopressin

Umxholo

• Ngaphambi kokusebenzisa i-desmopressin nasal,
• Impumlo yedesmopressin inokubangela iziphumo ebezingalindelekanga. Fowunela ugqirha wakho ukuba ngaba ezi mpawu zilandelayo zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Desmopressin nasal inokubangela ukuba i-hyponatremia isoyikise ubomi (inqanaba eliphantsi le-sodium egazini lakho). Tshela ugqirha wakho ukuba unayo okanye wakha wanayo inqanaba eliphantsi le-sodium egazini lakho, unxaniwe ixesha elininzi, usele izixa ezikhulu zolwelo, okanye ukuba une-syndrome ye-antidiuretic hormone engafanelekanga (SIADH; imeko apho umzimba uvelisa khona kakhulu into ethile yendalo ebangela ukuba umzimba ugcine amanzi), okanye isifo sezintso. Xelela ugqirha wakho ukuba unentsholongwane, umkhuhlane, okanye isisu okanye isifo samathumbu ngokugabha okanye urhudo. Tshela ugqirha wakho ukuba ufumana oku kulandelayo ngexesha lonyango lwakho: intloko ebuhlungu, isicaphucaphu, ukugabha, ukungazinzi, ukutyeba, ukutyeba kokutya, ukuba nochuku, ukudinwa, ukozela, isiyezi, ukuxinana kwezihlunu, ukuxhuzula, ukudideka, ukulahleka kwengqondo, okanye ukubona izinto ezingekhoyo .

Xelela ugqirha wakho ukuba uthatha i-loop diuretic ("iipilisi zamanzi") ezinjenge-bumetanide, furosemide (Lasix), okanye i-torsemide; i-inhaled steroid efana ne-beclomethasone (Beconase, QNasl, Qvar), budesonide (Pulmicort, Rhinocort, Uceris), fluticasone (Advair, Flonase, Flovent), okanye mometasone (Asmanex, Nasonex); okanye i-steroid yomlomo efana ne-dexamethasone, i-methylprednisolone (iMedrol), okanye i-prednisone (iRayos). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi i-desmopressin nasal ukuba usebenzisa okanye uthatha elinye lala mayeza.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo zokujonga amanqanaba esodiyamu ngaphambi kwaye ngexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwidesmopressin nasal.

Thetha nogqirha wakho malunga nomngcipheko (s) wokusebenzisa i-desmopressin nasal.

Impumlo yedesmopressin (DDAVP^®) isetyenziselwa ukulawula iimpawu zohlobo oluthile lwesifo seswekile i-insipidus ('isifo seswekile samanzi'; imeko apho umzimba uvelisa umchamo omkhulu ngokungaqhelekanga). Idesmopressinnasal (DDAVP^®ikwasetyenziselwa ukulawula ukunxanwa okugqithisileyo kunye nokuhamba kwenani elikhulu ngokungaqhelekanga lomchamo elinokuthi lenzeke emva kokonzakala kwentloko okanye emva kweentlobo ezithile zotyando. Impumlo yedesmopressin (Noctiva^®) isetyenziselwa ukulawula ukuchama rhoqo ebusuku kubantu abadala abavusa ubuncinci amaxesha ama-2 ngobusuku bonke ukuchama. Impumlo yedesmopressin (Uqikelelo^®) isetyenziselwa ukumisa ezinye iintlobo zokopha kubantu abane-hemophilia (imeko apho igazi lingagugi ngesiqhelo) kunye nesifo se-von Willebrand (isifo sokopha) esinamanqanaba athile egazi. Impumlo ye-Desmopressin ikudidi lwamayeza abizwa ngokuba ziihomoni ezibulala iintsholongwane. Isebenza ngokutshintsha i-vasopressin, ihomoni eveliswa emzimbeni ukunceda ukulinganisa isixa samanzi kunye netyuwa.

Impumlo ye-Desmopressin iza njengamanzi alawulwa ngempumlo ngokusebenzisa ityhubhu yomqolo (ityhubhu encinci yeplastiki ebekwe empumlweni ukuze isebenzise amayeza), kunye nesitshizi sempumlo. Ihlala isetyenziswa kube kathathu ngemini. Xa desmopressin ngeempumlo (Uqikelelo^®) isetyenziselwa ukunyanga i-hemophilia kunye nesifo se-von Willebrand, i-1 (2) yokutshiza inikwa yonke imihla. Ukuba uStimate^® isetyenziswa ngaphambi kotyando, ihlala inikwa iiyure ezi-2 ngaphambi kwenkqubo. Xa desmopressin ngeempumlo (Noctiva^®) isetyenziselwa ukunyanga rhoqo ukuchama ebusuku, isitshizi esinye sidla ngokunikwa ngasekhohlo okanye ekunene kwimpumlo imizuzu engama-30 ngaphambi kokuba ulale. Sebenzisa i-desmopressin nasal kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-nasal desmopressin ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

I-Desmopressin nasal spray (i-Noctiva) iyafumaneka kumandla amabini ahlukeneyo. Ezi mveliso azinakutshintshwa enye nenye. Ngalo lonke ixesha ugcwaliswa ngugqirha, qiniseka ukuba uyifumene imveliso efanelekileyo. Ukuba ucinga ukuba ufumene amandla angalunganga, thetha nogqirha wakho kunye nosokhemisti kwangoko.

Ugqirha wakho unokukuqala kwidosi esezantsi ye-desmopressin nasal kwaye uhlengahlengise idosi yakho ngokuxhomekeke kwimeko yakho. Landela le miyalelo ngononophelo.

Ukuba uza kusebenzisa isitshizi sempumlo, kuya kufuneka ujonge ulwazi lomenzi ukuze ufumane ukuba zingaphi izitshizi ezinebhotile yakho. Gcina umkhondo wenani lezitshizi ozisebenzisayo, ngaphandle kweziprayimari zokuqala. Yilahle ibhotile emva kokuba usebenzise inani elichaziweyo lokufafaza, nokuba linamayeza, kuba izitshizi ezongezelelweyo zisenokungabinayo idosi epheleleyo yamayeza. Ungazami ukuhambisa amayeza aseleyo kwenye ibhotile.

Ngaphambi kokuba usebenzise impumlo ye-desmopressin okokuqala, funda imiyalelo ebhaliweyo eza nonyango. Qiniseka ukuba uyayiqonda indlela yokulungisa ibhotile ngaphambi kokusetyenziswa kokuqala kunye nendlela yokusebenzisa isitshizi okanye ityhubhu yomqolo. Buza ugqirha wakho okanye usokhemesti ukuba unayo nayiphi na imibuzo malunga nendlela yokusebenzisa eli yeza.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-desmopressin nasal,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-desmopressin, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-desmopressin nasal spray. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nezinye ezi zinto zilandelayo: iasprini kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); carbamazepine (i-Equetro, iTegretol, iTeril); chlorpromazine; amanye amayeza asetyenziswa empumlweni; lamotrigine (Lamictal); i-narcotic (opiate) amayeza entlungu; i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (i-Celexa), i-escitalopram (i-Lexapro), i-fluoxetine (i-Prozac, i-Sarafem), i-fluvoxamine, i-paroxetine (i-Paxil), kunye ne-sertraline (i-Zoloft); i-thiazide diuretics ('iipilisi zamanzi') ezinjengehydrochlorothiazide (iMicrozide, iimveliso ezininzi zokudibanisa), indapamide, kunye ne-metolazone (iZaroxolyn); okanye i-tricyclic antidepressants (’mood elevators’) ezinje ngeamitriptyline, desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), okanye trimipramine (Surmontil). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ngaba unengxaki yokusilela kwentliziyo, uxinzelelo lwegazi oluphezulu, okanye isifo sentliziyo. Ugqirha wakho uya kukuxelela ukuba ungasebenzisi i-desmopressin nasal.
• xelela ugqirha wakho ukuba ukhe wagcina umchamo okanye i-cystic fibrosis (isifo esizalwe naso esidala iingxaki ngokuphefumla, ukwetyisa, kunye nokuzala). Xelela ugqirha wakho ukuba ubusandula ukwenziwa utyando lwentloko okanye lobuso, kwaye ukuba unempumlo egobileyo okanye erhabaxa, inezikrelemnqa okanye ukudumba kwangaphakathi kwempumlo, okanye i-atrophic rhinitis (imeko apho ulusu lwempumlo luyancipha kwaye ingaphakathi lempumlo ligcwele zizikrufu ezomileyo). Fowunela ugqirha wakho ukuba ukhulisa impumlo egxunyekiweyo okanye ebalekayo nangaliphi na ixesha ngexesha lonyango lwakho.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa i-desmopressin, tsalela ugqirha wakho.

Ugqirha wakho unokukuxelela ukuba unciphise inani lolwelo oselayo, ngakumbi ngokuhlwa, ngexesha lonyango lwakho nge-desmopressin. Landela izikhokelo zikagqirha wakho ngononophelo ukunqanda iziphumo ebezingalindelekanga ezimandundu.

Ukuba usebenzisa i-desmopressin nasal (DDAVP^®okanye (Stimate^®) kwaye uphose idosi, sebenzisa idosi ephosiweyo kwakamsinya nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Ukuba usebenzisa i-nasmopressin nasal (Noctiva^®) kwaye ulahle idosi, tsiba idosi ephosiweyo kwaye uthathe idosi elandelayo ngexesha lakho eliqhelekileyo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

Impumlo yedesmopressin inokubangela iziphumo ebezingalindelekanga. Fowunela ugqirha wakho ukuba ngaba ezi mpawu zilandelayo zinzima okanye azihambi:

• isisu esibuhlungu
• isilungulela
• ubuthathaka
• ubunzima bokulala okanye ukulala
• imvakalelo efudumeleyo
• impumlo
• Intlungu yempumlo, ukungonwabi, okanye ukuxinana
• ukurhawuzelela okanye ukujonga ukukhanya
• umqolo obuhlungu
• umqala obuhlungu, ukukhohlela, ukugodola, okanye ezinye iimpawu zosulelo
• ukugungxula

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• ukugabha
• iintlungu zesifuba
• ngokukhawuleza okanye ukubetha kwentliziyo
• irhashalala
• urhwebo
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya

Impumlo ye-Desmopressin inokubangela ezinye iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ufumana naziphi na iingxaki ezingaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina izitshizi zempumlo kwisitya esangena kuso, sivale ngci, kwaye singenakufikelela ebantwaneni.

Gcina okuqinisekileyo^® impumlo yokufafaza ime nkqo kwiqondo lobushushu elingaphaya kwe-25 ° C; lahla isitshizi sempumlo kwiinyanga ezi-6 emva kokuyivula.

Gcina i-DDAVP^® ngeempumlo ngokuthe nkqo kuma-20 ukuya kuma-25 ° C. Gcina i-DDAVP^® ityhubhu yomthambo kwi-2 ukuya kwi-8 ° C; iibhotile ezivaliweyo zizinzile iiveki ezi-3 ukuya kuma-20 ukuya kuma-25 ° C.

Ngaphambi kokuvula iNoctiva^® ukutshiza ngeempumlo, gcina nkqo nge-2 ukuya kwi-8 ° C. Emva kokuvula iNoctiva^®, gcina isitshizi sempumlo simile kuma-20 ukuya kuma-25 ° C; yilahle emva kweentsuku ezingama-60.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukudideka
• ukozela
• intloko ebuhlungu
• ubunzima bokuchama
• ukukhawuleza ukutyeba
• ukuxhuzula

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuqonda^®¶
• I-DDAVP^® Impumlo
• I-Minirin^® Impumlo^¶
• Noctiva^® Impumlo
• Ukuqina^® Impumlo

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.