Inaliti yeLeuprolide

Umxholo

• Ngaphambi kokufumana inaliti ye-leuprolide,
• Inaliti yeLeuprolide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

Inaliti yeLeuprolide (Eligard, Lupron Depot) isetyenziselwa ukunyanga iimpawu ezinxulunyaniswa nomhlaza weprostate. Inaliti yeLeuprolide (iLupron Depot-PED, Fensolvi) isetyenziselwa abantwana abaneminyaka emi-2 ubudala okanye ngaphezulu ukunyanga ukufikisa kwangaphambili (i-CPP; imeko ebangela amantombazana [ahlala engaphantsi kweminyaka eyi-8 ubudala) kunye namakhwenkwe [ihlala ingaphantsi kweminyaka eli-9 ubudala] ukungena ebusheni ngokukhawuleza, okukhokelela ekukhuleni ngokukhawuleza kwethambo kunye nokukhula kweempawu zesondo). Inaliti yeLeuprolide (iLupron Depot) isetyenziswa yodwa okanye elinye iyeza (norethindrone) ukunyanga i-endometriosis (imeko apho uhlobo lwethishu eligcina isibeleko [isibeleko] lukhula kwezinye iindawo zomzimba kwaye lubangele iintlungu, ukuya exesheni okunzima okanye okungaqhelekanga. [amaxesha], kunye nezinye iimpawu). Inaliti yeLeuprolide (iLupron Depot) ikwasetyenziswa namanye amayeza ukunyanga i-anemia (inani elisezantsi kuneliqhelekileyo leeseli ezibomvu zegazi) elibangelwa sisibeleko se-fibroids (ukukhula okungadibaniyo nesibeleko). Inaliti yeLeuprolide ikwiklasi yamayeza abizwa ngokuba yi-gonadotropin-releasing hormone (GnRH) agonists. Isebenza ngokunciphisa inani lamahomoni athile emzimbeni.

Inaliti yeLeuprolide iza njengokumiswa kokusebenza ixesha elide (iLupron) okujojowe nge-intramuscularly (kwisihlunu) ngugqirha okanye umongikazi kwiofisi yezonyango okanye eklinikhi kwaye ihlala inikwa kube kanye ngenyanga (ILupron Depot, iLupron Depot-PED) okanye yonke Iinyanga ezi-3, 4, okanye ezi-6 (iLupron Depot-3 inyanga, iLupron Depot-PED-3 inyanga, iLupron Depot-4 inyanga, iLupron Depot-Inyanga ye-6). Inaliti yeLeuprolide iyeza njengokumiswa okuthatha ixesha elide (i-Eligard) ejojowe (ngaphantsi nje kwesikhumba) ngugqirha okanye umongikazi kwiofisi yezonyango okanye eklinikhi kwaye ihlala inikwa iinyanga ezi-1, 3, 4, okanye ezi-6. Inaliti yeLeuprolide iza nokunqunyanyiswa okwenzeka ixesha elide (iFensolvi) ejojowe (ngaphantsi nje kwesikhumba) ngugqirha okanye umongikazi kwiofisi yezonyango okanye eklinikhi kwaye ihlala inikwa rhoqo emva kweenyanga ezi-6. Ugqirha wakho uya kukuxelela ukuba luya kuhlala ixesha elingakanani unyango lwakho ngenaliti ye-leuprolide. Xa isetyenziswa ebantwaneni abanokufikisa kwangaphambili, inaliti ye-leuprolide (iLupron Depot-PED, iLupron Depot-PED-3 inyanga, iFensolvi) iya kumiswa ngugqirha womntwana wakho ngaphambi kweminyaka eli-11 ubudala kumantombazana nakwiminyaka eli-12 yamakhwenkwe.

Ukuba ufumana i-leuprolide yokumiswa kwexesha elide (i-Eligard) njengenaliti engaphantsi, unokuqaphela iqhuma elincinci kwindawo apho wawutofa khona inaliti xa wawufumana kuqala iyeza. Eli qhuma kufuneka ekugqibeleni lihambe.

I-Leuprolide inokubangela ukonyuka kwamahomoni athile kwiiveki zokuqala ezimbalwa emva kwenaliti. Ugqirha wakho uya kukujonga ngononophelo kuyo nayiphi na impawu ezintsha okanye eziya zisiba mbi ngeli xesha.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-leuprolide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-leuprolide, goserelin (Zoladex), histrelin (Supprelin LA, Vantas), nafarelin (Synarel), triptorelin (Triptodur, Trelstar), nawaphi na amanye amayeza, okanye nasiphi na isithako senaliti ye-leuprolide. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: amayeza athile okubetha kwentliziyo ngokungaqhelekanga njenge-amiodarone (Cordarone), disopyramide (Norpace), procainamide (Procanbid), quinidine, kunye ne-sotalol (iBetapace, iBetapace AF, iSorine); ibuproprion (Aplenzin, Forfivo, Wellbutrin, kwiContrave); amayeza okuxhuzula; i-steroids yomlomo efana ne-dexamethasone (Hemady), i-methylprednisolone (iMedrol), kunye ne-prednisone (iRayos); kunye nokukhetha i-serotonin reuptake inhibitors (i-SSRIs) efana ne-citalopram (i-Celexa), i-escitalopram (i-Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, kwi-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil) kunye ne-sertraline (i-Zoloft). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-leuprolide, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba wopha ngokungaqhelekanga kwilungu lobufazi. Ugqirha wakho unokukuxelela ukuba ungasebenzisi inaliti ye-leuprolide.
• xelela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho ukhe wanaso okanye wakha wanamathambo (imeko apho amathambo ebhityile kwaye kunokwenzeka ukuba aphuke); ukuba unembali yokusela utywala okanye ukusebenzisa iimveliso zecuba ixesha elide; okanye ukuba ukhe wanalo uxinzelelo, ukuxhuzula, ukudumba kwengqondo, umhlaza osasazeke emqolo (umqolo), isifo seswekile, ukuthintela umchamo (ukuvaleka okubangela ubunzima bokuchama), igazi kumchamo wakho, ixesha elide le-QT (inqabile ingxaki yentliziyo enokubangela ukubetha kwentliziyo ngokungaqhelekanga, ukuphelelwa ngamandla, okanye ukufa ngesiquphe), isifo se-cerebrovascular (ukuvala okanye ukwenza buthathaka imithambo yegazi ngaphakathi kwengqondo okanye ekhokelela kwingqondo), isifo sentliziyo, okanye inqanaba eliphantsi le-potassium, calcium, okanye i-magnesium igazi lakho.
• Kuya kufuneka uyazi ukuba i-leuprolide ayizukusetyenziswa kwabasetyhini abakhulelweyo, abanokukhulelwa, okanye abancancisayo. Tshela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuncancisa. Ugqirha wakho unokwenza uvavanyo lokukhulelwa ukuze aqiniseke ukuba awukhulelwanga xa uqala ukufumana inaliti ye-leuprolide. Kuya kufuneka usebenzise indlela ethembekileyo yokulawula ukuzalwa ukuthintela ukukhulelwa ngelixa ufumana inaliti ye-leuprolide. Thetha nogqirha wakho malunga neentlobo zolawulo lokuzalwa ezilungele wena, kwaye uqhubeke nokusebenzisa ulawulo lokuzalwa nangona ungafaneleki ukuba sexesheni rhoqo ngexesha lonyango lwakho. Ukuba ucinga ukuba ukhulelwe ngelixa ufumana inaliti ye-leuprolide, tsalela umnxeba kwangoko. Inaliti yeLeuprolide inokwenzakalisa umntwana ongekazalwa.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa ixesha lokuqeshwa ukuze ufumane inaliti ye-leuprolide, kuya kufuneka ubize umnikezeli wakho wezempilo kwangoko ukuze abuye kwakhona.

Inaliti yeLeuprolide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukudinwa
• ukutshisa okutshisayo (ngesiquphe ubushushu obushushu okanye obushushu bomzimba), ukubila, okanye ukubamba
• ukuthamba kwebele, iintlungu, okanye utshintsho kubungakanani besifuba kubo bobabini nabasetyhini
• ukukhutshwa kwilungu lobufazi, ukoma, okanye ukurhawuzelela kwabasetyhini
• ukubona (ukuphuma kwegazi lobufazi) okanye ukuya exesheni (amaxesha)
• ukwehla ngokobungakanani bamatyhalarha
• ukwehla kubuchule bezesondo okanye umnqweno
• ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi
• intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
• iintlungu, ukutshisa, ukugruzuka, ukuba bomvu, okanye ukuqina kwindawo apho kunikwe khona inaliti
• utshintsho kubunzima
• intlungu yesihlunu okanye edibeneyo
• ukuphuma kwempumlo, ukukhohlela, umqala obuhlungu, okanye iimpawu ezifana nomkhuhlane
• ifiva
• isisu esibuhlungu
• ukuqhina
• intloko ebuhlungu
• induna
• ukudakumba
• ukungakwazi ukulawula iimvakalelo kunye notshintsho lweemvakalelo rhoqo
• uvalo
• imvakalelo ngokubanzi yokungonwabi okanye ukungonwabi
• ubunzima ngememori

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ukurhawuzelela, irhashalala, okanye imihlathi
• ubunzima bokuphefumla okanye ukugwinya
• iintlungu ezingalweni, ngasemva, esifubeni, entanyeni, okanye emhlathini
• intetho ecothayo okanye enzima
• isiyezi okanye isiqaqa
• ubuthathaka, ukuba ndindisholo, okanye ukungakwazi ukuhambisa ingalo okanye umlenze
• iintlungu zethambo
• ukuchama kabuhlungu, rhoqo, okanye kunzima
• igazi kumchamo
• ukunxanwa okugqithisileyo
• ubuthathaka
• umlomo owomileyo
• isicaphucaphu
• ukugabha
• umphefumlo onuka iziqhamo
• ukuncipha kwengqondo
• ngequbuliso intloko
• ukungaboni kakuhle
• utshintsho lombono
• ubunzima bokuhambisa amehlo
• ukujingisa iinkophe
• ukudideka
• ukuxhuzula

Inaliti yeLeuprolide inokubangela ukwehla koxinano lwamathambo akho elinokonyusa amathuba amathambo aphukileyo. Thetha nogqirha wakho malunga nemingcipheko yokusebenzisa eli yeza kunye nokufumanisa ukuba ungenza ntoni ukunciphisa le mngcipheko.

Kubantwana abafumana inaliti ye-leuprolide (I-Lupron Depot-PED, i-Fensolvi) yokufikisa ngaphambi kwexesha, iimpawu ezintsha okanye eziba mandundu zokukhula ngokwesondo zinokwenzeka kwiiveki zokuqala zonyango. Kumantombazana afumana inaliti ye-leuprolide (Lupron Depot-PED) yokufikisa ngaphambi kwexesha, ukuqala kokuya exesheni okanye ukubona (ukuphuma kwegazi kwilungu lobufazi) kunokubakho kwiinyanga ezimbini zokuqala zonyango. Ukuba ukopha kuyaqhubeka ngaphezulu kwenyanga yesibini, tsalela ugqirha wakho.

Inaliti yeLeuprolide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu kwaye athathe imilinganiselo ethile ukujonga impendulo yomzimba wakho kwisitofu se-leuprolide. Iswekile yegazi lakho kunye nehemoglobin eglycosylated (HbA1c) inokujongwa rhoqo.

Buza usokhemesti wakho ukuba unayo nayiphi na imibuzo onayo malunga nenaliti ye-leuprolide.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Eligard^®
• Ifensolvi^®
• ILupron^®
• ILupron Depot^®
• ILupron Depot-PED^®
• Ipakethi yeLupaneta^® (njengemveliso yokudibanisa equlathe iLeurprolide, Norethindrone)

• Leuprorelin Acetate