I-Didanosine

Umxholo

• Ngaphambi kokuba uthathe i-didanosine,
• I-Didanosine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba olu phawu lubi okanye aluhambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zikhankanywe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Didanosine inokubangela isifo sepancreatitis esibi okanye esisongela ubomi (ukudumba kwepancreas). Xelela ugqirha wakho ukuba uyasela okanye wakha wasela izixa ezikhulu zotywala kwaye ukuba ukhe wanaso isifo sokuphazamiseka kwepancreatitis, ipancreas okanye isifo sezintso. isicaphucaphu, ukugabha, okanye umkhuhlane.

I-Didanosine inokubangela ingozi esongela ubomi kwisibindi kunye nemeko esongela ubomi ebizwa ngokuba yi-lactic acidosis (i-lactic acid egazini). Umngcipheko wokuba uza kuphuhlisa i-lactic acidosis unokuphakama ukuba ungumfazi, ukuba utyebe kakhulu, okanye ukuba uye wanyangwa ngamayeza e-HIV ixesha elide. Xelela ugqirha wakho ukuba ukhe unesifo sesibindi. Xelela ugqirha wakho ukuba uthatha istavudine (iZerit). Ugqirha wakho uya kukuxelela ukuba ungathathi i-didanosine ukuba uthatha eli yeza. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango olukhawulezileyo: ukuphefumla kancinci; ukuphefumla ngokukhawuleza; utshintsho ekubetheni kwentliziyo; isicaphucaphu; ukugabha; ukuphelelwa ngumdla wokutya; ukuhla ukusinda; urhudo; iintlungu kwindawo ephezulu yesisu sakho; ukopha okungaqhelekanga okanye ukugruzuka; ubumthubi besikhumba okanye amehlo; umchamo omnyama-mnyama; ukukhanya okukhanyayo; ukudinwa kakhulu; izandla neenyawo ezibandayo okanye ezinombala oluhlaza okwesibhakabhaka; okanye iintlungu zemisipha.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-didanosine.

Thetha nogqirha wakho malunga neengozi zokuthatha i-didanosine.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-didanosine kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

I-Didanosine isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. UDidanosine ukwiklasi yamayeza abizwa ngokuba yi-nucleoside reverse transcriptase inhibitors (NRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-didanosine ingayinyangi i-HIV, inokuwanciphisa amathuba okuba ube ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezinzulu okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa (ukusasaza) intsholongwane kagawulayo kwabanye abantu.

I-Didanosine iza njengokukhutshwa okwandisiweyo (ukusebenza ixesha elide) njengezingxobo kunye nesisombululo somlomo (ulwelo) ukuthatha ngomlomo. Isisombululo somlomo sihlala sithathwa kanye okanye kabini ngemini imizuzu engama-30 ngaphambi okanye iiyure ezi-2 emva kokutya. Iifomsile zokukhutshwa ezandisiweyo zihlala zithathwa kanye ngemini kwisisu esingenanto. Thatha i-didanosine ujikeleze ixesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-didanosine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi, okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuba usebenzisa iifomsile zokukhupha ezandisiweyo, ziginye ziphelele; musa ukwahlula, ukuhlafuna, ukutyumza, ukwaphula, okanye ukuzinyibilikisa. Tshela ugqirha wakho ukuba awukwazi ukugwinya ii-capsules ezikhutshiweyo ezandisiweyo.

Ukuba uthatha isisombululo somlomo, kuya kufuneka usishukumise kakuhle ngaphambi kokuba usetyenzise ukuxuba amayeza ngokulinganayo. Sebenzisa icephe yokulinganisa idosi okanye ikomityi ukulinganisa inani elichanekileyo lolwelo kwidosi nganye, hayi icephe lekhaya eliqhelekileyo.

I-Didanosine ilawula usulelo lwe-HIV kodwa ayilunyangi. Qhubeka nokuthatha i-didanosine nokuba uziva uphilile. Sukuyeka ukuthatha i-didanosine ngaphandle kokuthetha nogqirha wakho. Ukuba uphosa idosi okanye uyeke ukuthatha i-didanosine, imeko yakho kunokuba nzima ukunyanga.

I-Didanosine ngamanye amaxesha isetyenziswa namanye amayeza ukunceda ukuthintela usulelo kubasebenzi bokhathalelo lwempilo okanye abanye abantu abaye bavezwa ngengozi yi-HIV. Thetha nogqirha wakho malunga neengozi zokusebenzisa la mayeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-didanosine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-didanosine, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-didanosine okanye isisombululo somlomo. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha i-allopurinol (Aloprim, Lopurin, Zyloprim), okanye i-ribavirin (iCopegus, iRebetol, iVirazole). Ugqirha wakho uya kukuxelela ukuba ungathathi i-didanosine ukuba uthatha elinye okanye omabini la mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nawaphi na amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye noku kulandelayo: ii-antacids ezine-aluminium okanye i-magnesium (Maalox, Mylanta, nezinye): Atazanvir (Reyataz); ii-antibiotics ezinje nge-ciprofloxacin (Cipro), gatifloxacin (Tequin), moxifloxacin (Avelox), ofloxacin (Floxin), pentamidine (Nebupent, Pentam), sulfamethoxazole kunye ne-trimethoprim (Bactrim, Septra), kunye ne-tetracycline (Sumycin); ikhabazitaxel (Jevtana); dapsone (Aczone); delavirdine (Umshicileli); I-docetaxel (iTaxotere); ganciclovir (icytovene); ihydroxyurea (iDroxia, iHydrea); indinavir (iCrixivan); imethadone (iDolophine, iMethadose); i-nelfinavir (iViracept); iPaclitaxel (Abraxane, iTaxol); ipentamidine (Nebupent, Pentam); i-ranitidine (iZantac); i-ritonavir (iNorvir); I-sulfamethoxazole kunye ne-trimethoprim (iBactrim, Septra). i-tenofovir (iViread); i-tipranavir (iAptivus); ivalganciclovir (iValcyte); okanye i-vincristine (Marqibo). Ugqirha wakho unokufuna ukutshintsha amayeza akho, utshintshe xa uthatha amayeza akho, okanye ujonge ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-didanosine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe wanayo iperipheral neuropathy (ukuba ndindisholo, ukurhawuzelela, ukutshisa, okanye iintlungu ezandleni okanye ezinyaweni, okanye ukunciphisa amandla okuva ubushushu okanye ukubamba ezandleni nasezinyaweni) okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-didanosine, tsalela ugqirha wakho.Akufanele uncancise xa wosulelwe yi-HIV okanye ukuba uthatha i-didanosine.
• Kuya kufuneka uyazi ukuba i-didanosine inokubangela iziphumo ebezingalindelekanga ekufuneka ziphathwe kwangoko ngaphambi kokuba zibe mandundu. Abantwana abathatha i-didanosine abanako ukukuxelela malunga neziphumo ebezingalindelekanga abazivayo. Ukuba unika i-didanosine emntwaneni, buza ugqirha womntwana ukuba unokwazi njani ukuba umntwana unale miphumo mibi.
• Kuya kufuneka uyazi ukuba unokulahleka kwamanqatha omzimba ebusweni bakho, imilenze, iingalo, kunye neempundu. Thetha nogqirha wakho ukuba uyalubona olu tshintsho.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye eziba mandundu emva kokuqala unyango kunye ne-didanosine, qiniseka ukuxelela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Didanosine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba olu phawu lubi okanye aluhambi:

• intloko ebuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zikhankanywe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukuba ndindisholo, ukurhawuzelela, ukutshisa, okanye iintlungu ezandleni okanye ezinyaweni
• utshintsho lombono
• ubunzima ekuboneni imibala ngokucacileyo

I-Didanosine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina ii-capsules ze-didanosine kwisikhongozelo abangena kuzo, zivalwe ngokuqinileyo, kwaye zingenakufikelelwa ngabantwana. Zigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina isisombululo somlomo se-didanosine kwifriji, uvale ngokuqinileyo, kwaye ulahle naliphi na iyeza elingasetyenziswanga emva kweentsuku ezingama-30.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• urhudo
• ukuba ndindisholo, ukurhawuzelela, ukutshisa, okanye iintlungu ezandleni okanye ezinyaweni
• isicaphucaphu
• ukugabha
• Ukuphelelwa ngumdla wokutya
• isisu esibuhlungu
• ukudumba kwesisu
• intlungu yesihlunu okanye edibeneyo
• ukudinwa kakhulu
• ubuthathaka
• isiyezi
• intloko elula
• ukukhawuleza, ukukhawuleza okanye ukungahambi kakuhle kwentliziyo
• ukuphefumla okunzulu okanye okukhawulezayo
• ukuqhawukelwa ngumphefumlo
• Umchamo omnyama otyheli okanye omdaka
• ukopha okungaqhelekanga okanye ukugruzuka
• ukugabha into enegazi okanye ebonakala ngathi yindawo yekhofi
• izitulo ezimnyama
• mthubi ulusu okanye amehlo
• ndiziva ndibanda
• ifiva
• Iimpawu ezinjengomkhuhlane

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Gcina unikezelo lwe-didanosine ngesandla. Sukulinda de uphelelwe ngamayeza ukuze uphinde uzalise amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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• IVidex^®

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