Itraconazole

Umxholo

• Ngaphambi kokuba uthathe i-itraconazole,
• I-Itraconazole inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, yeka ukuthatha i-itraconazole kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

I-Itraconazole inokubangela ukusilela kwentliziyo (imeko apho intliziyo ingenakupompa igazi elaneleyo emzimbeni). Tshela ugqirha wakho ukuba ukhe wasilela kwentliziyo. Ugqirha wakho unokukuxelela ukuba ungayithathi itraconazole. Xelela ugqirha wakho ukuba ukhe wahlaselwa yintliziyo; ukubetha kwentliziyo ngokungaqhelekanga; okanye naluphi na olunye uhlobo lwentliziyo, imiphunga, isibindi okanye isifo sezintso. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, yeka ukuthatha i-itraconazole kwaye ubize ugqirha ngoko nangoko: ukuphefumla kancinci; ukukhohlela phezulu koomhlophe okanye bepinki; ubuthathaka; ukudinwa okugqithisileyo; ukubetha kwentliziyo ngokukhawuleza; ukudumba kweenyawo, amaqatha okanye imilenze; ukuvuka ebusuku; kunye nokuzuza ubunzima ngesiquphe.

Musa ukuthatha i-cisapride (Propulsid) (ayifumaneki e-US), disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), eplerenone (Inspra), amayeza ohlobo lwe-ergot anjenge-dihydroergotamine (DHE, Migranal), ergotamine ( Ergomar, eCafergot, eMigergot), imethylergometrine (iMethergine); felodipine (Plendil), irinotecan (Camptosar), ivabradine (Corlanor), levomethadyl acetate (Orlaam) (ayifumaneki e-US), lovastatin (Altoprev, in Advicor), lurasidone (Latuda), methadone (Dolophine, Methadose), midazolam kuthathwe ngomlomo), nisoldipine (Sular), pimozide (Orap), quinidine (eNuedexta), ranolazine (Ranexa), simvastatin (Zocor, eSimcor, eVytorin), ticagrelor (Brilinta), kunye netriazolam (Halcion) ngelixa uthatha itraconazole nakwiiveki ezi-2 emva koko. Xelela ugqirha wakho ukuba unesifo sezintso okanye sesibindi kwaye uthatha nawaphi na amayeza alandelayo: colchicine (Colcrys, Mitigare), fesoterodine (Toviaz), solifenacin (Vesicare), okanye telithromycin (Ketek). Ukuthatha la mayeza nge-itraconazole kunokubangela iingxaki zentliziyo ezinzulu kubandakanya nokwandiswa kwe-QT (isingqisho sentliziyo esingaqhelekanga esinokukhokelela ekuphelelweni lithemba, ekubanjweni sisazela, ekuthinjweni, okanye ekufeni ngesiquphe).

Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-itraconazole.

Iipilisi ze-Itraconazole zisetyenziselwa ukunyanga usulelo lokungunda kwimiphunga enokuthi isasazeke emzimbeni wonke. Iipilisi ze-Itraconazole ziyasetyenziselwa ukunyanga usulelo lokungunda lweenzipho. Amacwecwe e-Itraconazole kunye neephilisi zisetyenziselwa ukunyanga usulelo lokungunda kweenzwane. Isisombululo somlomo se-Itraconazole (ulwelo) sisetyenziselwa ukunyanga usulelo lwegwele lomlomo nomqala okanye lwe-esophagus (ityhubhu edibanisa umqala nesisu). I-Itraconazole ikudidi lwee-antifungals ezibizwa ngokuba zii-triazoles. Isebenza ngokunciphisa ukukhula komngundo obangela usulelo.

I-Itraconazole iza njengecapsule, ithebhulethi, kunye nesisombululo (ulwelo) ukuthatha ngomlomo. Ukuba uthatha i-itraconazole ukunyanga usulelo lomngundo emiphungeni, iicapsule zihlala zithathwa ngexesha okanye kanye emva kwesidlo esipheleleyo isihlandlo esinye okanye ezibini ngemini okungenani iinyanga ezintathu. Nangona kunjalo, ukuba uthatha i-itraconazole ukunyanga usulelo olubi kakhulu emiphungeni, iifomsile zinokuthathwa ngokutya kathathu ngemini kwiintsuku zokuqala ezi-3 zonyango kwaye emva koko uthathe kanye okanye kabini ngemini ngokutya ubuncinci Iinyanga ezi-3. Ukuba uthatha i-itraconazole ukunyanga usulelo lokungunda kweenzwane (kubandakanya okanye ngaphandle kosulelo lwenzipho), iifomsile okanye iipilisi zihlala zithathwa kanye ngemini ngokutya okupheleleyo kwiiveki ezili-12. Ukuba uthatha i-itraconazole ukunyanga usulelo lokungunda lwenzipho kuphela, iifomsile zihlala zithathwa kabini ngemini ngokutya okupheleleyo kwiveki e-1, utsibe iiveki ezi-3, emva koko uthathe kabini ngemini ngokutya iveki. Isisombululo somlomo se-Itraconazole sihlala sithathwa kwisisu esingenanto kanye okanye kabini ngemini iiveki ezi-1 ukuya kwezi-4 okanye ngamanye amaxesha ubude. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-itraconazole ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukuginya yonke itraconazole njengezingxobo; sukuwavula, uwahlafune, okanye uwaqhekeze.

Ugqirha wakho angakuxelela ukuba uthathe iipilisi ze-itraconazole ngesiselo esihlwahlwazayo se-cola ukuba uneemeko ezithile zonyango okanye uthatha naliphi na kula mayeza alandelayo: cimetidine; ifototidine (iPepcid); i-nizatidine (iAxid); Iiproton-pump inhibitors ezinje nge-esomeprazole (Nexium, eVimovo), lansoprazole (Prevacid, Prevpac), omeprazole (Prilosec, e Zegerid), pantoprazole (Protonix), rabeprazole (AcipHex), okanye ranitidine (Zantac). Landela le miyalelo ngononophelo.

Ukuthatha isisombululo somlomo se-itraconazole sosulelo lomngundo emlonyeni okanye emqaleni, swish 10 milliliters (about 2 tablespoons) yesisombululo emlonyeni wakho imizuzwana eliqela uginye. Phinda xa kukho imfuneko yokuba uthathe idosi yakho yonke.

Iifomsile ze-Itraconazole kunye nesisombululo somlomo zingena emzimbeni ngeendlela ezahlukeneyo kwaye zisebenza ukunyanga iimeko ezahlukeneyo. Musa ukufaka endaweni njengezingxobo ulwelo okanye ulwelo njengezingxobo. Qiniseka ukuba usokhemesti wakho ukunika imveliso ye-itraconazole eyalelwe ngugqirha wakho.

Ukuba uthatha i-itraconazole ukunyanga usulelo lwesikhonkwane, iinzipho zakho ngekhe zibonakale ziphilile de zikhule iinzipho ezintsha. Kungathabatha ukuya kwiinyanga ezi-6 ukukhula kweenzipho ezintsha ukuya kuthi ga kwiinyanga ezili-12 ukukhula kweenzipho ezintsha, ke awunakulindela ukubona ukuphucuka ngexesha lonyango lwakho okanye iinyanga ezininzi emva koko. Qhubeka uthathe i-itraconazole nokuba awuboni kuphucuka.

Qhubeka uthathe i-itraconazole de ugqirha akuxelele ukuba uyeke nokuba uziva uphilile. Sukuyeka ukuthatha i-itraconazole ngaphandle kokuthetha nogqirha wakho. Ukuba uyeka ukuthatha i-itraconazole kwakamsinya, usulelo lwakho lunokubuya emva kwexesha elifutshane.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

I-Itraconazole ngamanye amaxesha isetyenziselwa ukunyanga ezinye iintlobo zosulelo lokungunda kunye nokuthintela usulelo lokungunda kubantu abanentsholongwane kaGawulayo (i-HIV) okanye bafumana i-immunodeficiency syndrome (i-AIDS). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli chiza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-itraconazole,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-itraconazole; amanye amayeza okubola njenge-fluconazole (Diflucan), ketoconazole (Nizoral), okanye voriconazole (Vfend); naliphi na elinye iyeza, okanye nasiphi na isithako seemveliso ze-itraconazole. Ukuba uthatha isisombululo somlomo se-itraconazole, xelela ugqirha wakho ukuba ngaba uxabisa amayeza e-saccharin okanye e-sulfa. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba uthatha la mayeza alandelayo okanye uwathathe kwiiveki ezi-2 ezidlulileyo ngaphambi kokuba uqale unyango nge-itraconazole: carbamazepine (Epitol, Tegretol, Teril, others); efavirenz (Sustiva, eAtripla); isoniazid (Laniazid, eRifamate, eRifater); irifabutin (Mycobutin); irifampicin; nevirapine (Viramune); phenobarbital; kunye ne phenytoin (Dilantin, Phenytek).
• xelela ugqirha wakho okanye usokhemesti ukuba uthatha amayeza alandelayo: aliskiren (Tekturna, eAmturnide, Tekamlo, kunye neTekturna HCT), apixaban (Eliquis), axitinib (Inlyta), colchicine (Colcrys, Mitigare), dabrafemob (Taflinar), darifenacin (Enablex), dasatinib (Sprycel), everolimus (Afinitor, Zortress), ibrutinib (Imbruvica), nilotinib (Tasigna), rivaroxaban powder (Xarelto), salmeterol (Serevent), sildenafil (kuphela uphawu lweRevatio olusetyenziselwa isifo semiphunga), simeprevir ( ), sunitinib (Sutent), tamsulosin (Flomax, eJalyn), temsirolimus (Torisel), trabectedin (Yondelis), kunye ne vardenafil (Staxyn, Levitra). Ugqirha wakho unokukuxelela ukuba ungawathathi la mayeza ngexesha lonyango lwakho kunye nakwiiveki ezi-2 emva konyango lwakho nge-itraconazole.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nalawo angabhaliswanga, iivithamini, izongezo zesondlo kunye neemveliso zamayeza owathathayo okanye oceba ukuwathatha. Qinisekisa ukukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zilandelayo: amayeza okubulala iintsholongwane afana ne-ciprofloxacin (Cipro), i-clarithromycin (i-Biaxin, kwi-PrevPac), i-erythromycin (i-EES Ery-Tab, abanye), kunye ne-telithromycin (Ketek) ; i-anticoagulant ('' blood thinner '') efana ne-warfarin (Coumadin, Jantoven); alprazolam (Xanax); Aprepitant (Hlomela); aripiprazole (Yenza); atorvastatin (Lipitor, eCaduet, eLiptruzet); ibortezomib (Velcade); i-bosentan (iTracleer); i-budesonide (i-Entocort EC, iPulmicort, iUceris); buprenorphine (Buprenex, Butrans, kwi-Bunavail; abanye); buspirone; iciclesonide (Alvesco, Omnaris, Zetonna); Iililostazol (Pletal); cinacalcet (iSensipar); icyclosporine (Gengraf, Neoral, Sandimmune); dabigatran (Pradaxa); dexamethasone; diazepam (Valium); idigoxin (Lanoxin); I-docetaxel (iDocefrez, iTaxotere); i-eletriptan (i-Relpax); erlotinib (iTarceva); fentanyl (Actiq, Duragesic, Fentora, Subsys, nabanye); ifesoterodine (Toviaz); i-fluticasone (iFlovent, eAdvair); gefitinib (Iressa); haloperidol (iHaldol); I-HIV protease inhibitors kubandakanya indinavir (Crixivan), darunavir (Prezista) ethathwe nge-ritonavir, fosamprenavir (Lexiva) ethathwe nge-ritonavir, kunye ne-saquinavir (i-Invirase); imatinib (iGleevac); ixabepilone (Ixempra Kit); lapatinib (iTykerb); i-maraviroc (i-Selzentry); imeloxicam (iMobic); imethylprednisolone (iMedrol); nadolol (eCorgard, eCorzide); Oxybutynin (Ditropan XL, Oxytrol); i-oxycodone (iOxaydo, iOxycontin, kwiPercodan; abanye); iponatinib (Iclusig); ipraziquantel (iBiltricide); iquetiapine (iSeroquel); i-ramelteon (iRozerem); repaglinide (Prandin, kwi Prandimet); riociguat (Adempas); irisperidone (iRisperdal); isaxagliptin (Kombiglyze XR, Onglyza); i-sirolimus (iRapamune); i-solifenacin (Vesicare); itacrolimus (Astagraf, Prograf); tadalafil (Adcirca, Cialis); itolterodine (Detrol); vardenafil (Levitra, Staxyn); i-verapamil (Calan, Covera, Verelan PM, eTarka), vinblastine, vincristine (Marqibo Kit), kunye ne vinorelbine (Navelbine). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-itraconazole, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• ukuba uthatha i-antacid, yithathe iyure enye ngaphambi okanye iiyure ezi-2 emva kokuba uyithathile itraconazole.
• xelela ugqirha wakho ukuba ukhe wakha wanemiqathango ekhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO ,, i-cystic fibrosis (isifo esizelwe ngaphakathi esibangela iingxaki ngokuphefumla, ukwetyisa, kunye nokuzala), nayiphi na imeko enciphisa inani leasidi esiswini sakho, okanye i-HIV.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Akufanele uthathe i-itraconazole ukunyanga i-nail fungus ukuba ukhulelwe okanye unokukhulelwa. Ungaqala ukuthatha i-itraconazole ukunyanga i-fungus yesikhonkwane kuphela ngomhla wesibini okanye wesithathu wexesha lokuya esikhathini xa uqinisekile ukuba awukhulelwe. Kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-2 emva koko. Ukuba ukhulelwe ngelixa uthatha i-itraconazole ukunyanga nayiphi na imeko, tsalela ugqirha wakho.
• Kuya kufuneka uyazi ukuba i-itraconazole inokukwenza ube nesiyezi okanye ubangele ukungaboni kakuhle okanye umbono ophindwe kabini. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.

Thetha nogqirha wakho malunga nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Itraconazole inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukuqhina
• irhasi okanye ukudumba
• isilungulela
• incasa engathandekiyo
• iintsini ezibuhlungu okanye ezophayo
• intloko ebuhlungu
• isiyezi
• ukubila
• iintlungu zemisipha okanye ubuthathaka
• intlungu edibeneyo
• ukunciphisa umnqweno wesini okanye amandla
• uvalo
• ukudakumba
• ukuphuma kwempumlo kunye nezinye iimpawu ezibandayo
• ifiva
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ukungaboni kakuhle okanye umbono ophindwe kabini
• kukhala ezindlebeni
• ukungakwazi ukulawula ukuchama okanye ukuchama ngaphezu kwesiqhelo

Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, yeka ukuthatha i-itraconazole kwaye ubize ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukudinwa kakhulu
• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• isisu esibuhlungu
• ukugabha
• mthubi ulusu okanye amehlo
• umchamo omnyama
• izitulo ezimhlophe
• iimvakalelo zokuba ndindisholo, ukurhawuzelela, ukuhlaba, ukutshisa, okanye ukukhasa esikhumbeni
• ukulahlekelwa kwindlebe
• ukwanda kokuziva ekukhanyeni
• ukuphazamiseka kwesikhumba
• ukulahlekelwa kwindlebe
• irhashalala
• urhwebo
• ukurhawuzelela
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuphefumla okanye ukugwinya

Esinye sezithako kwisisombululo somlomo se-itraconazole sabangela umhlaza kwezinye iintlobo zezilwanyana zaselebhu. Ayaziwa nokuba abantu abathatha isisombululo se-itraconazole banomngcipheko okhulayo wokuba nomhlaza. Thetha nogqirha wakho malunga nemingcipheko yokuthatha isisombululo se-itraconazole.

I-Itraconazole inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obungaphaya, ukukhanya, kunye nobumanzi (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-itraconazole.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho. Ukuba usenempawu zosulelo emva kokuba ugqibe i-itraconazole, tsalela ugqirha wakho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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