Umbhali: Joan Hall
Umhla Wokudalwa: 6 Eyomdumba 2021
Hlaziya Umhla: 19 Eyenkanga 2024
Anonim
CPIC guideline for fluvastatin and SLCO1B1, CYP2C9
Ividiyo: CPIC guideline for fluvastatin and SLCO1B1, CYP2C9

Umxholo

I-Fluvastatin isetyenziswa kunye nokutya, ukwehla kobunzima, kunye nokuzilolonga ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo kunye nokufa icala kunye nokunciphisa amathuba okuba kufuneka utyando lwentliziyo kubantu abanesifo sentliziyo okanye abasemngciphekweni wokuhlaselwa sisifo sentliziyo. I-Fluvastatin ikwasetyenziselwa ukunciphisa isixa sezinto ezinamafutha ezinje nge-low-density lipoprotein (LDL) cholesterol ('bad cholesterol') kunye ne-triglycerides egazini kunye nokunyusa inani le-lipoprotein (HDL) cholesterol ('cholesterol elungileyo' ') egazini. I-Fluvastatin inokusetyenziselwa ukunciphisa inani le-cholesterol kunye nezinye izinto ezinamafutha egazini ebantwaneni nakwishumi elivisayo abaneminyaka eli-10 ukuya kweli-17 ubudala abane-heterozygous hypercholesterolemia (imeko ezuzwe njengelifa apho i-cholesterol ayinakususwa emzimbeni ngesiqhelo). I-Fluvastatin ikudidi lwamayeza abizwa ngokuba yi-HMG-CoA reductase inhibitors (statins). Isebenza ngokunciphisa imveliso ye-cholesterol emzimbeni ukunciphisa inani le-cholesterol elinokwakha kwiindonga zeemithambo kunye nokuvimba ukuhamba kwegazi ukuya entliziyweni, kwingqondo nakwezinye iindawo zomzimba.


Ukuqokelelwa kwecholesterol kunye namafutha ecaleni kweendonga zemithambo yakho (inkqubo eyaziwa njenge-atherosclerosis) inciphisa ukuhamba kwegazi kwaye, ke, unikezelo lweoksijini entliziyweni yakho, kwingqondo nakwamanye amalungu omzimba wakho. Ukunciphisa izinga lakho legazi le-cholesterol kunye namafutha nge-fluvastatin ibonakalisiwe ukuthintela isifo sentliziyo, i-angina (iintlungu zesifuba), ukubetha, kunye nokuhlaselwa yintliziyo.

I-Fluvastatin iza njengecapsule kunye nokukhutshwa okwandisiweyo (ukuhlala ixesha elide) kwithebhulethi oza kuyithatha ngomlomo. I-capsule ihlala ithathwa kunye okanye ngaphandle kokutya kanye ngemini ngexesha lokulala okanye kabini ngemini. Ithebhulethi yokukhululwa eyandisiweyo ihlala ithathwa kanye ngemini kunye okanye ngaphandle kokutya. Thatha i-fluvastatin ngeenxa zonke zexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-fluvastatin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi zokukhululwa ezandisiweyo; ungahluleli, ungahlaleli, okanye uzityumze.


Ugqirha wakho unokukuqala kwidosi ephantsi ye-fluvastatin kwaye ngokuthe ngcembe wandise idosi yakho, hayi ngaphezulu kwesinye kwiiveki ezi-4.

Qhubeka nokuthatha i-fluvastatin nokuba uziva uphilile. Sukuyeka ukuthatha i-fluvastatin ungakhange uthethe nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-fluvastatin,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-fluvastatin, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifluvastatin capsules okanye iipilisi ezandisiweyo zokukhupha. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-anticoagulants ('blood thinner') ezifana ne-warfarin; cimetidine (iTagamet); icolchicine (iiColcrys); i-cyclosporine (iNeoral, iSandimmune); diclofenac (iCataflam, Voltaren); idigoxin (Lanoxin); i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin); i-fluconazole (iDiflucan), i-glyburide (iDiaBeta, iGlynase, iMicronase); ketoconazole (Nizoral); omeprazole (Prilosec); amanye amayeza athoba i-cholesterol anje nge cholestyramine (Questran), fenofibrate (Tricor), gemfibrozil (Lopid), kunye ne-niacin (nicotinic acid, Niacor, Niaspan); phenytoin (Dilantin); i-ranitidine (iZantac); irifampin (Rifadin, Rimactane); kunye ne-spironolactone (Aldactone). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-fluvastatin, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba unesifo sesibindi. Ugqirha wakho uya ku-odola uvavanyo lwelabhoratri ukuze abone ukuba isibindi sakho sisebenza kakuhle kangakanani na nokuba awucingi ukuba unesifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-fluvastatin ukuba unesifo sesibindi okanye ukuba iimvavanyo zibonisa ukuba ungakhula isifo sesibindi.
  • xelela ugqirha wakho ukuba usela ngaphezulu kweziselo ezinxilisayo ezi-2 ngosuku, ukuba uneminyaka engama-65 ubudala okanye ngaphezulu, kwaye ukuba wakhe wanesifo sesibindi okanye wakha wanemithambo okanye ubuthathaka, isifo seswekile, uxinzelelo lwegazi, ukuxhuzula, okanye isifo sedlala okanye isifo sezintso.
  • xelela ugqirha wakho ukuba ukhulelwe, okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa uthatha i-fluvastatin. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwe ngelixa uthatha i-fluvastatin, yeka ukuthatha i-fluvastatin kwaye ubize ugqirha ngoko nangoko. I-Fluvastatin inokulimaza umbungu.
  • musa ukuncancisa xa uthatha la mayeza.
  • ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-fluvastatin. Ukuba ulaliswe esibhedlele ngenxa yosulelo okanye ukonzakala okukhulu, xelela ugqirha okunyangayo ukuba uthatha i-fluvastatin.
  • Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-fluvastatin. Utywala bunokunyusa umngcipheko weziphumo ebezingalindelekanga ezimandundu.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaphezulu kweeyure ezili-12 ukusukela kwidosi yakho yokugqibela, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Fluvastatin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • intloko ebuhlungu
  • isilungulela
  • ubunzima bokulala okanye ukulala
  • intlungu yesono
  • ukukhohlela
  • ukulahleka kwememori okanye ukulibala
  • ukudideka

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane uncedo lonyango olungxamisekileyo:

  • iintlungu zemisipha, ukuthamba, okanye ubuthathaka
  • ukunqongophala kwamandla
  • ifiva
  • mthubi ulusu okanye amehlo
  • iintlungu kwinxalenye ephezulu yesisu
  • umchamo omnyama ngombala
  • isicaphucaphu
  • ukudinwa kakhulu
  • ukopha okungaqhelekanga okanye ukugruzuka
  • Ukuphelelwa ngumdla wokutya
  • Iimpawu ezinjengomkhuhlane
  • irhashalala
  • urhwebo
  • ukurhawuzelela
  • ubunzima bokuphefumla okanye ukugwinya
  • ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
  • ukudinwa

I-Fluvastatin inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unoku-odola uvavanyo lwelabhoratri ngexesha lonyango lwakho, ngakumbi ukuba uvelisa iimpawu zomonakalo wesibindi.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-fluvastatin.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • U-Lescol®
  • U-Lescol® XL
Ukuhlaziywa kokugqibela-11/15/2017

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