Indinavir

Umxholo

• Ngaphambi kokuba uthathe indinavir,
• I-Indinavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba olu phawu lubi okanye aluhambi:
• I-Indinavir inokubangela iziphumo ebezingalindelekanga. Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Indinavir isetyenziswa kunye namanye amayeza ukunyanga intsholongwane kaGawulayo. I-Indinavir ikudidi lwamayeza abizwa ngokuba zii-protease inhibitors. Isebenza ngokunciphisa inani le-HIV egazini. Nangona i-indinavir ingayinyangi i-HIV, inokuwanciphisa amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kunye nezifo ezinxulumene ne-HIV ezinje ngezifo ezomeleleyo okanye umhlaza. Ukuthatha la mayeza kunye nokwabelana ngesondo okukhuselekileyo nokwenza olunye utshintsho kwindlela yokuphila kunokunciphisa umngcipheko wokuhambisa intsholongwane kagawulayo kwabanye abantu.

I-Indinavir iza njengepilisi yokuthatha ngomlomo. Ihlala ithathwa qho kwiiyure ezisi-8 (kathathu ngemini). Thatha indinavir ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha indinavir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Thatha i-indinavir kwisisu esingenanto, iyure e-1 ngaphambi kokutya okanye iiyure ezi-2 emva kokutya, ngamanzi, iskim okanye ubisi olungafaki, ijusi, ikofu, okanye iti. Nangona kunjalo, ukuba i-indinavir iyasicaphukisa isisu sakho, inokuthathwa ngesidlo esilula, esinjenge-toast eyomileyo okanye ii-cornflakes ezinobisi olungenamikhono okanye olungelulo. Thetha nogqirha wakho okanye usokhemesti malunga nokutya okunokuthathwa nge-indinavir.

Musa ukutyumza okanye ukuhlafuna i-capsule, kodwa inokuvulwa kwaye ixutywe ne-puree yeziqhamo (njengebhanana).

Qhubeka nokuthatha indinavir nokuba uziva uphilile. Sukuyeka ukuthatha indinavir ngaphandle kokuthetha nogqirha wakho.

Ugqirha wakho unokufuna ukuphazamisa unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho nge-indinavir.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

I-Indinavir ikwasetyenziswa ngamanye amaxesha ngokudibanisa namanye amayeza ukunyanga abasebenzi bokhathalelo lwempilo kunye nabanye abantu abachaphazeleka kusulelo lwe-HIV emva kokudibana ngengozi negazi eline-HIV, izicwili, okanye olunye ulwelo lomzimba. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli chiza kwimeko yakho.

Ngaphambi kokuba uthathe indinavir,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-indinavir, nawaphi na amanye amayeza, okanye nasiphi na isithako esivela kwiipilisi ze-indinavir. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo: alfuzosin (Uroxatral); alprazolam (Xanax); amiodarone (Nexterone, iPacerone); i-cisapride (Propulsid) (ayifumaneki e-U.S.); amayeza ohlobo lwe-ergot anje nge-dihydroergotamine (iDHE 45, Migranal), ergonovine (Ergotrate), ergotamine (Ergomar, eCafergot, eMigergot), kunye ne-methylergonovine (Methergine); I-lovastatin (Altoprev, Mevacor); ilurasidone (iLatuda); midazolam (Iindinyana) ngomlomo; ipimozide (Orap); sildenafil (kuphela uphawu lweRevatio olusetyenziselwa isifo semiphunga); isimvastatin (iZocor, eVytorin); okanye i-triazolam (Halcion). Ugqirha wakho uya kukuxelela ukuba ungathathi i-indinavir.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: bosentan (Tracleer); iicalcium-channel blocker ezinje nge-amlodipine (Norvasc, eAmturnide, eTekamlo), felodipine, nicardipine, kunye nifedipine (Adalat, Afeditab, Procardia); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, nabanye); cholesterol-ukunciphisa amayeza (ii-statins) ezinjenge-atorvastatin (Lipitor, eCaduet) kunye ne-rosuvastatin (Crestor); i-clarithromycin (i-Biaxin, kwi-PrevPac); icolchicine (Colcrys, Mitigare, kwiCol-Probenecid); dexamethasone; i-fluconazole (iDiflucan); i-fluticasone (Flonase, Flovent, eAdvair, eDymista); itraconazole (Onmel, Sporanox); ketoconazole (Extina, Nizoral, Xolegel); amanye amayeza e-HIV kubandakanya atazanavir (Reyataz, e-Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, e-Atripla), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e Kaletra, e Viekira Pak), nase saquinavir (Inkuthazo); amayeza okubetha kwentliziyo ngokungaqhelekanga njenge-lidocaine (Glydo, Xylocaine) kunye nequinidine (eNuedexta); amayeza athintela amajoni omzimba anje ngecyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), kunye netacrolimus (Astagraf XL, Envarsus XR, Prograf); i-midazolam (iVenkile) ngenaliti; ezithile ze-phosphodiesterase inhibitors (PDE-5 inhibitors) ezisetyenziselwa ukungasebenzi kakuhle kwe-erectile njenge-sildenafil (Viagra), tadalafil (Adcirca, Cialis), kunye nevardenafil (Levitra, eStaxyn); phenobarbital; phenytoin (iDilantin, iPhenytek); iquetiapine (iSeroquel); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane, eRifamate, eRifater); isalmeterol (iSerevent, eAdvair); ithenda kunye ne-venlafaxine (Effexor). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-indinavir, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• ukuba uthatha i-didanosine (Videx), yithathe ubuncinci iyure enye ngaphambi okanye emva kwe-indinavir.
• xelela ugqirha wakho ukuba ukhe okanye wakha wanesifo (hemophilia (ukuphazamiseka kwegazi apho igazi lingagutyungeki kakuhle), isifo seswekile, okanye isifo sezintso okanye sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa uthatha i-indinavir, tsalela ugqirha wakho. Akufuneki uncancise xa wosulelwe yi-HIV okanye ukuba uthatha i-indinavir.
• Kuya kufuneka uyazi ukuba amanqatha omzimba wakho anganyuka okanye ahambele kwiindawo ezahlukeneyo zomzimba wakho ezinje ngamabele akho, umqolo ongasentla, intamo, isifuba, kunye nendawo yesisu. Ukuphulukana namafutha emilenzeni, ezingalweni nasebusweni nako kunokwenzeka.
• Kuya kufuneka uyazi ukuba unokufumana i-hyperglycemia (inyuka kwiswekile esegazini lakho) ngelixa uthatha eli yeza, nokuba awukabinaso isifo seswekile. Xelela ugqirha wakho kwangoko ukuba unayo nayiphi na kwezi mpawu zilandelayo ngelixa uthatha i-indinavir: ukunxanwa okugqithisileyo, ukuchama rhoqo, ukulamba kakhulu, umbono ophuthileyo, okanye ubuthathaka. Kubaluleke kakhulu ukubiza ugqirha wakho nje ukuba ube nazo naziphi na ezi mpawu, kuba iswekile ephezulu yegazi enganyangekiyo inokubangela imeko embi ebizwa ngokuba yi ketoacidosis. I-Ketoacidosis inokuba sengozini yobomi ukuba ayinyangwa kwangoko. Iimpawu zeketoacidosis zibandakanya umlomo owomileyo, isicaphucaphu kunye nokugabha, ukuphefumla kancinci, ukuphefumla okunuka iziqhamo kunye nokuncipha kwengqondo.
• Kuya kufuneka uyazi ukuba ngelixa uthatha amayeza ukunyanga usulelo lwe-HIV, amajoni akho omzimba angomelela kwaye aqale ukulwa nezinye izifo ezazisele zisemzimbeni wakho. Oku kunokubangela ukuba ube neempawu zolu sulelo. Ukuba uneempawu ezintsha okanye ezibaxekileyo nangaliphi na ixesha kunyango lwakho nge-indinavir, qiniseka ukuxelela ugqirha wakho.

Sela ubuncinci ii-ounces ezingama-48 (1.5 yeelitha), ezimalunga nesithandathu seoyile (240-milliliter) iiglasi, zamanzi okanye ezinye izinto ezingamanzi rhoqo emva kweeyure ezingama-24.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.

Ukuba uphose idosi ngaphantsi kweeyure ezi-2, thatha idosi ephosiweyo kwakamsinya nje ukuba uyikhumbule. Nangona kunjalo, ukuba uphosa idosi ngaphezulu kweeyure ezingama-2, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Indinavir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba olu phawu lubi okanye aluhambi:

• utshintsho ngengqondo yokungcamla

I-Indinavir inokubangela iziphumo ebezingalindelekanga. Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ukurhawuzelela
• Ukuxobuka okanye ukudumba kolusu
• umqolo obuhlungu
• intlungu kwicala lomzimba wakho
• phakathi ukuya kwintlungu esiswini
• igazi kumchamo
• iintlungu zemisipha okanye ubuthathaka
• isicaphucaphu
• ukudinwa kakhulu
• ukopha okungaqhelekanga okanye ukugruzuka
• Ukuphelelwa ngumdla wokutya
• iintlungu kwindawo ephezulu yesisu sakho
• Iimpawu ezinjengomkhuhlane
• Umchamo omnyama otyheli okanye omdaka
• mthubi ulusu okanye amehlo
• ukuqhawukelwa ngumphefumlo
• ukubetha kwentliziyo ngokukhawuleza
• ukudideka
• isiyezi
• intloko ebuhlungu
• ubumhlophe

I-Indinavir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. I-desiccant (i-arhente yokomisa) ifakiwe kunye neepilisi zakho; gcina oku kwibhotile yakho yeyeza maxa onke. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• intlungu kwicala lomzimba wakho
• igazi kumchamo
• isicaphucaphu
• ukugabha
• urhudo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yakho kwi-indinavir.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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• IDV