Umbhali: Randy Alexander
Umhla Wokudalwa: 23 Utshazimpuzi 2021
Hlaziya Umhla: 21 Eyenkanga 2024
Anonim
Acral Lentiginous Melanoma Dermatopathology
Ividiyo: Acral Lentiginous Melanoma Dermatopathology

Umxholo

Yintoni iacral lentiginous melanoma?

I-Acral lentiginous melanoma (ALM) luhlobo lwe-melanoma enobungozi. I-malignant melanoma luhlobo lomhlaza wolusu olwenzeka xa iiseli zolusu ezibizwa ngokuba yimelanocytes ziba ngumhlaza.

IiMelanocytes ziqulathe umbala wakho wolusu (owaziwa ngokuba yi-melanin okanye i-pigment). Kolu hlobo lwe-melanoma, igama elithi "acral" libhekisa kwimeko yesifo se-melanoma ezintendeni okanye ematheni.

Igama elithi "lentiginous" lithetha ukuba ibala le-melanoma limnyama kakhulu kunesikhumba esijikelezileyo. Inomda obukhali phakathi kwesikhumba esimnyama kunye nesikhumba esikhanyayo esijikelezileyo. Lo mahluko kumbala yenye yeempawu ezibonakalayo zolu hlobo lwe-melanoma.

I-ALM lolona hlobo luqhelekileyo lwe-melanoma kubantu abanesikhumba esimnyama kunye nabo baseAsia. Nangona kunjalo, inokubonwa kuzo zonke iintlobo zolusu. I-ALM kunokuba nzima ukuyibona ekuqaleni, xa isiziba esimnyama senziwe sincinci kwaye sikhangeleka ngathi sincinci kwibala okanye ukugruzuka. Ukuchongwa kwangoko kunye nonyango kubalulekile.

Iimpawu ze-Acral lentiginous melanoma

Olona phawu lubonakalayo lwe-ALM ngesiqhelo yindawo emnyama yesikhumba ejikelezwe lulusu oluhlala luluhlobo lwakho oluqhelekileyo lolusu. Kukho umda ocacileyo phakathi kwesikhumba esimnyama kunye nesikhumba esikhanyayo esijikelezileyo. Ngokuqhelekileyo uya kufumana indawo efana nale okanye ngeenxa zonke ezandleni nasezinyaweni, okanye kwiibhedi zezikhonkwane.


Amabala e-ALM awanakusoloko enombala omnyama okanye ade abe mnyama kwaphela. Amanye amabala anokuba bomvu okanye o-orenji ngombala- la abizwa ngokuba yi-amelanotic (okanye ayina-pigmented).

Kukho imiqondiso emihlanu onokujonga ngayo ukuba unqume ukuba ingaba indawo inokukrokrela i-melanoma (ngokuchasene ne-non-cancer). La manyathelo kulula ukuba awakhumbule ngegama elithi ABCDE:

  • Iasymmetry: Iziqingatha ezibini zebala azifani, oko kuthetha ukuba zinokwahluka ngokobukhulu okanye imilo. Iinyumasi ezinganomdlavuza zihlala zijikeleze imilo okanye zinobungakanani obufanayo kunye nokumila kumacala omabini.
  • Isitenxo somda: Umda ojikeleze indawo awulingani okanye ujike. Iintsumpa ezingenawo umhlaza zihlala zinemida ethe tye, ichazwe ngokucacileyo, kwaye iqinile.
  • Ukwahluka kombala: Indawo yenziwe ngeendawo ezinemibala emininzi emdaka, luhlaza okwesibhakabhaka, mnyama, okanye eminye imibala efanayo. Iinyumasi ezingenawo umhlaza zihlala zinombala omnye (zihlala zimdaka).
  • Ububanzi obukhulu: Indawo inkulu kunekota ye-intshi (0.25 intshi, okanye iimilimitha ezi-6) ngeenxa zonke. Ii-moles ezingezizo zomhlaza zihlala zincinci kakhulu.
  • Ukuguquka: Indawo iye yakhula inkulu okanye inemibala engaphezulu kunaleyo yayiqala ukuvela kulusu lwakho. Iintsumpa ezingenawo umhlaza zihlala zingakhuli okanye zitshintshe umbala kakhulu njengendawo ye-melanoma.

Umphezulu wendawo ye-ALM unokuqalisa ngokugudileyo kwaye ube bumpier okanye ube rougher njengoko uvela. Ukuba ithumba liqala ukukhula lisuka kwiiseli zolusu ezinomhlaza, ulusu luya kubhabha ngakumbi, lube nebala, kwaye lube rhabaxa ukuya ekuphathweni.


I-ALM inokubonakala ijikeleze iinzipho zakho kunye neenzwane. Xa oku kusenzeka, ibizwa ngokuba yi-subungual melanoma. Ungakuqaphela ukubola okwenzekileyo kwisikhonkwane sakho kunye namabala okanye imigca yokutshintsha kombala esolulela kwi-cuticle kunye nolusu apho luhlangana khona nesikhonkwane. Oku kubizwa ngokuba ngumqondiso kaHutchinson. Njengoko indawo ye-ALM ikhula, isikhonkwane sakho sinokuqalisa ukuqhekeka okanye ukuqhekeka ngokupheleleyo, ngakumbi njengoko siqhubela phambili kwinqanaba elilandelayo.

I-Acral lentiginous melanoma ibangela

I-ALM yenzeka ngenxa yokuba ii-melanocytes kulusu lwakho ziba mandundu. I-tumor iya kuqhubeka ikhula kwaye isasazeka ide isuswe.

Ngokungafaniyo nezinye iintlobo ze-melanoma, i-acral lentiginous melanoma ayihambelani nokukhanya kwelanga okugqithileyo. Kukholelwa ukuba utshintsho kwimfuza lunegalelo kuphuhliso lwe-acral lentiginous melanoma.

Unyango lwe-Acral lentiginous melanoma | Unyango nolawulo

Amanqanaba okuqala

Ukuba i-ALM yakho isekumanqanaba okuqala kwaye incinci ngokwaneleyo, ugqirha wakho unokukwazi ukusika indawo ye-ALM kulusu lwakho ngokukhawuleza, kugqirha. Ugqirha wakho uya kunqumla ulusu olujikeleze indawo leyo. Ubungakanani besikhumba ekufuneka bususwe buxhomekeke kubukhulu beBelllow ye-melanoma, ebonisa ukuba i-melanoma ingena nzulu kangakanani. Oku kumiselwe ngemicroscopic.


Amanqanaba aphezulu

Ukuba i-ALM yakho inezinga elinzulu lokuhlasela, ii-lymph node zisenokufuna ukususwa. Ukuncitshiswa kwamanani kunokuba yimfuneko. Ukuba kukho ubungqina bokusasazeka okukude, njengakwezinye izitho, unokufuna unyango nge-immunotherapy. I-Immunotherapy ngamayeza e-biologic ajolise kwii-receptors kwi-tumor.

Uthintelo

Ukuba uqala ukubona iimpawu ze-ALM ngokusebenzisa umthetho we-ABCDE, jonga ugqirha wakho ngokukhawuleza ukuze bathathe i-biopsy yendawo kwaye bathathe isigqibo sokuba ingaba umhlaza unomhlaza. Njengalo naluphi na uhlobo lomhlaza okanye i-melanoma, ukulufumanisa kwangoko kunokunceda ekwenzeni unyango lube lula kunye nefuthe kwimpilo yakho.

Imbonakalo

Kumanqanaba aphambili, i-ALM kunokuba nzima ukunyanga nokulawula. I-ALM inqabile kwaye ayisoloko ibulala, kodwa ityala eliphambili linokukhokelela kwiindawo zezandla zakho okanye iinyawo ezifuna ukunqunyulwa ukuze umise umhlaza ekuqhubekeni phambili.

Ukuba ufunyaniswe kwangoko kwaye ufuna unyango lokumisa i-ALM ekukhuleni nasekusasazeni, umbono we-ALM unokulunga.

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